Shirley Zhang
Senior Scientist at Viking Therapeutics, Inc.- Claim this Profile
Click to upgrade to our gold package
for the full feature experience.
Topline Score
Bio
0
/5.0 / Based on 0 ratingsFilter reviews by:
Experience
-
Viking Therapeutics, Inc.
-
United States
-
Pharmaceutical Manufacturing
-
1 - 100 Employee
-
Senior Scientist
-
Aug 2023 - Present
-
-
-
Crown Bioscience
-
United States
-
Biotechnology Research
-
200 - 300 Employee
-
Study Director, Scientist III
-
Oct 2021 - Aug 2023
Lead scientist responsible for planning and execution of pre-clinical in vivo oncology studies in a CRO setting:- Manage multiple clients and client projects on different teams in a matrix environment- Provide scientific expertise for study design and protocol development for efficacy, PK, PD, tolerability, model development- Experience using PDX, CDX, syngeneic, humanized, GEMM models- Oversee details of technical execution, and communicate client instructions to internal teams- Analysis of study data, creation of study reports, and presentation of data to clients- Key point of contact between Crown Bioscience and global clients to provide regular data updates and timelines for project progress, milestones, and deadlines- Direct scientific operations and provide support for business development- Reporting of Key Performance Indicators (KPI) to site management- Conduct work in accordance to relevant regulations, including scientist/principal investigator role in IACUC committee to review protocols for animal welfare Show less
-
-
Study Coordinator Manager
-
Apr 2021 - Aug 2023
Manage a team of 11 study coordinators and junior study directors, including hiring, training, mentoring, task assignments, process improvement, identification and creation of new roles, performance reviews
-
-
Study Director, Scientist II
-
Apr 2021 - Oct 2021
-
-
Study Director, Scientist I
-
Jan 2020 - Apr 2021
-
-
-
UC Irvine
-
United States
-
Higher Education
-
700 & Above Employee
-
PHD
-
2013 - 2020
Researching biophysical cues of the cellular environment and how they can be utilized to study, detect, and treat disease states such as cancer and fibrosis.- Engineered mechano-responsive cell-based therapeutic platform to detect and treat cancer and fibrosis in vivo by targeting the unique physical properties of the tumor microenvironment- Established murine disease models for primary tumor, metastasis, patient-derived xenograft, and liver fibrosis- Utilized lentiviral transduction to engineer various cell types, including stem cells, to express functional and reporter genes- Optimized histological assays to evaluate and characterize cell and tissue samples for target expression and co-localization- Fabricated polyacrylamide hydrogels with tunable stiffness as cell culture substrates- Analyzed tissue samples using multichannel fluorescent imaging, image scanning and stitching- Optimized method of sampling tissue stiffness using atomic force microscopy- Generated successful patent application, publications, grant proposals, and presentations- Mentored undergraduate and graduate students; managed lab inventory, safety protocols, budgets Show less
-
-
Teaching Assistant, Department of Biomedical Engineering
-
2017 - 2017
-
-
-
UCSD
-
Research Services
-
500 - 600 Employee
-
Undergraduate Researcher
-
2009 - 2013
Undergraduate research at UCSD included work with micro and nanofluidics, tissue histology and immunohistochemistry, small animal models, biomaterials, and image and data analysis.- Designed and conducted independent experiments to characterize naturally-derived and synthetic biomaterials for treatment of myocardial infarction- Assisted in small animal surgery of rats for cardiac injections and tissue collection- Analyzed cardiac tissue samples using histology, immunohistochemistry, and fluorescent imaging- Created original figures and diagrams featured in publications Show less
-
-
Teaching Assistant, Department of Biology
-
Sep 2011 - Dec 2011
Undergraduate TA position for upper division genetics class with 600+ students. Held discussion sections, review sections, office hours, wrote and gave exams, and grading.
-
-
-
The University of Auckland
-
New Zealand
-
Higher Education
-
700 & Above Employee
-
Student Researcher
-
Jun 2012 - Aug 2012
A study abroad research opportunity through Pacific Rim Experiences for Undergraduates program. Studied localization of intracellular proteins in cardiomyocytes using super-resolution stochastic imaging. A study abroad research opportunity through Pacific Rim Experiences for Undergraduates program. Studied localization of intracellular proteins in cardiomyocytes using super-resolution stochastic imaging.
-
-
Education
-
UC Irvine
Doctor of Philosophy - PhD, Bioengineering and Biomedical Engineering -
UC Irvine
Master of Science - MS, Bioengineering and Biomedical Engineering -
University of California San Diego
Bachelor of Science - BS, Bioengineering and Biomedical Engineering