Experience

Novo Nordisk Foundation Center for Basic Metabolic Research

• Denmark
• Research Services
• 100 - 200 Employee

• Research Assistant at The Single-Cell Omics Platform (SCOP)

  • Aug 2023 - Present

• Master Thesis Student

  • Feb 2023 - Aug 2023

  • Integrating unpaired single-cell ATAC-seq and RNA-seq data from public dataset (Tabula Sapiens and CATLAS) with multiome data through Seurat v4 and latest deep learning methods • Optimizing and benchmarking these different methods• Down-stream analysis of transcriptional regulation, cell type markers and single-cell genetic enrichment

• Project Student

  • Nov 2022 - Jan 2023

  • Clusteredandannotatedcelltypebasedonsingle-cell sequencing data(ATAC-seqandRNA-seq)through PCA, UMAP, SVD, and WNN methods• Establishedandcompareddifferentstatisticalmethods(shiftR, fGWAS, gChromVAR)for assessing single-cellGWAS enrichments based on 10x multiome data among different tissues, such as colon, liver, and muscle



Shanghai Jiao Tong University

• China
• Higher Education
• 700 & Above Employee

• Bachelor Thesis

  • Oct 2019 - May 2021

  • Demonstrated that de novo transcription is required for bacterial peptide flg22-induced stomatal immunity using pharmacological tools, transcriptional and translational inhibitors • Identified two plant hormone abscisic acid(ABA) receptors involved in flg22-mediated de novo transcription • Performed RNA-seq using Smart-seq2 to analyze genome-wide transcription in Arabidopsis stomatal guard cells protoplats in wild type and ABA receptor • Demonstrated that de novo transcription is required for bacterial peptide flg22-induced stomatal immunity using pharmacological tools, transcriptional and translational inhibitors • Identified two plant hormone abscisic acid(ABA) receptors involved in flg22-mediated de novo transcription • Performed RNA-seq using Smart-seq2 to analyze genome-wide transcription in Arabidopsis stomatal guard cells protoplats in wild type and ABA receptor



Minsheng Securities Co.,Ltd.

• China
• Investment Banking
• 1 - 100 Employee

• Assistant Investment Assistant

  • Jan 2021 - Mar 2021

  • Assistant Investment Assistant at Strategic Investment Department • Updated weekly report of Chinese pharmaceutical industry development including latest government policy, latest research progress, new drug application, pharma finance and investment news both China and international markets • Completed three independent analysis reports of antibody therapy, cell therapy and RNA interference therapy through analyzing their principles, development, market size, current products and competitors Show less



NYU Shanghai

• China
• Higher Education
• 300 - 400 Employee

• Summer Intern

  • Jul 2020 - Aug 2020

  • Hypothesized that the H2A.Z isoform gene H2AFV may be important to chromosome alignment through observing mitosis of H2A.Z RNAi knockdown in Hela cell line and generated siRNA-resistant stable cell line by constructing plasmid through molecular cloning • Detected off-target effects of RNAi by analyzing H2A.Z expression through western blotting • Hypothesized that the H2A.Z isoform gene H2AFV may be important to chromosome alignment through observing mitosis of H2A.Z RNAi knockdown in Hela cell line and generated siRNA-resistant stable cell line by constructing plasmid through molecular cloning • Detected off-target effects of RNAi by analyzing H2A.Z expression through western blotting