Shamitha Govind
Graduate Student at Institute of Molecular Biology (IMB)- Claim this Profile
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Bio
Experience
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Institute of Molecular Biology (IMB)
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Germany
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Research
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100 - 200 Employee
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Graduate Student
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Nov 2019 - Present
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Institute of Human Genetics
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Montpellier Area, France
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Graduate Student Research Assistant
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May 2018 - Dec 2018
Masters thesis on Drosophila germline stem cells and piwi-interacting RNAs. Masters thesis on Drosophila germline stem cells and piwi-interacting RNAs.
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Indian Institute of Science (IISc)
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India
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Research
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700 & Above Employee
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Undergraduate Research Assistant
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Jun 2017 - Apr 2018
with Prof. V. NagarajaGre proteins maintain genome integrity by resolving backtracked RNA Polymerases and allowing stalled transcription units to proceed. This project studies the essential requirement of Gre in the maintenance of cellular phenotype, growth characteristics and gene expression in Mycobacterium smegmatis.
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Undergraduate Research Assistant
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Mar 2017 - May 2017
with Prof. V. Nagaraja Generation of Rv3788 mutants through Overlapping PCR and molecular cloning:Rv3788 is a Gre protein homologue in Mycobacterium tuberculosis found to bind the secondary channel of RNAP and inhibit transcription. In this project, I created site-directed mutations using overlapping PCR in the amino acid sequence of Rv3788, expressed it in E.coli and purified the protein. The resulting changes in mutant protein’s activities provided necessary insight into the mechanism of Rv3788’s inhibitory function. Show less
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Tata Institute of Fundamental Research
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Research Services
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200 - 300 Employee
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Summer Internship
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May 2016 - Jun 2016
Validation of pab1 as a bonafide molecule responsible for cytokinesis checkpoint maintenance: with Dr. Mithilesh Mishra In Schizosaccharomyces pombe, the phosphatase Clp-1 encompasses a cytokinesis surveillance mechanism which is essential upon any cytokinetic challenge to the cell. The gene pab-1 was suspected to be a downstream effector of Clp-1. To validate this, pab-1’s essentiality in a background of artificially created damage to the cytokinetic ring was studied. Double mutants of pab-1 deletion and various temperature sensitive ring components were generated and checked for viability and phenotype. Show less
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Indian Institute of Science (IISc)
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Bengaluru Area, India
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Event Coordinator
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Jan 2016 - Jan 2016
Lasya 2016: National dance competition in IISc As a part of PRAVEGA: IISc's annual Undergraduate Science and Cultural festival Lasya 2016: National dance competition in IISc As a part of PRAVEGA: IISc's annual Undergraduate Science and Cultural festival
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Indian Institute of Science (IISc)
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India
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Research
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700 & Above Employee
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Summer Internship
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May 2015 - Jul 2015
Testing the cytotoxicity of areca nut aqueous extract on MCF7 cells Carried out the MTT tetrazolium reduction assay on MCF7 cells with various concentrations of Areca catechu extract to determine its minimum inhibitory concentration Testing the cytotoxicity of areca nut aqueous extract on MCF7 cells Carried out the MTT tetrazolium reduction assay on MCF7 cells with various concentrations of Areca catechu extract to determine its minimum inhibitory concentration
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Indian Institute of Science (IISc)
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Bangalore, India
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Event Coordinator
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Jan 2015 - Jan 2015
Lasya 2015: National dance competition in IISc As a part of PRAVEGA: IISc's annual Undergraduate Science and Cultural festival Lasya 2015: National dance competition in IISc As a part of PRAVEGA: IISc's annual Undergraduate Science and Cultural festival
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Education
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Indian Institute of Science (IISc)
Master of Science - MS, Biology, General -
Indian Institute of Science (IISc)
Bachelor of Science (Research), Biology