Experience

Inovarion

• France
• Research Services
• 1 - 100 Employee

• Senior Researcher

  • Jul 2018 - Present

  Région de Paris, France



INSERM UMR-S1139 -(ex U767) "Physiopathologie et Pharmacotoxicologique Placentaire Humaine"

• Impact of E352Q PPARγ mutation on transcriptional activity & placental development

  • Feb 2017 - Aug 2017

  Faculté de Pharmacie de Paris, Université Paris Descartes, Paris, France Group Leader Team: 1 technician, 1 PhD student Methods: cell culture, molecular biology, site directed mutagenesis,CRISPR/Cas9, siRNA Publications: 1 oral presentation, 3 communications

• Impact of phthalates on the placental development and functions

  • Jan 2015 - Jul 2016

  Faculté de Pharmacie de Paris, Université Paris Descartes, Paris, France Group Leader Funding: ANSES PhtalatPreg Team: 1 technician, 1 phD student Methods: toxicology, cell culture, molecular biology, lipidomics. Publications: 3 original articles (2 in Press), 1 article in progress, 3 articles in collaboration (1 submitted), 1 oral presentation, 3 communications

• Role of Annexin-A5 in the membrane repair and fusion of human trophoblast cells

  • Jan 2013 - Jul 2014

  Faculté de Pharmacie de Paris, Université Paris Descartes, Paris, France Funding: ANR PlacentA5 Methods: primary cell cultures, over-expression and function inhibition (GFP plasmid and siRNA transfection), site directed mutagenesis, cell live imaging Publications: 3 original articles, 4 articles in collaboration, 1 submitted article, 2 oral presentations, 13 communications

• Study of the M-DC8+ monocytes and TNFα+ cells distributions in the spleen of HIV infected patients.

  • Nov 2010 - Dec 2012

  Institut Cochin, Paris, France Funding: Sidaction Methods: immunofluorescence, confocal microscopy, flow cytometry Publications: 1 article in progress, 2 articles in collaboration, 7 communications



INSERM U767 "Grossesse normale et pathologique"

• Development of primary cultures of bovine extraembryonic cells

  • Oct 2008 - Mar 2010

  Faculté de Pharmacie, Paris, France -> new models for studies of proliferation, cell invasion and fusion processes Funding: PremUp Fundation Methods: primary cell cultures, immunofluorescence, confocal microscopy, molecular biology techniques Publications: 5 original articles (with 1 invitation), 3 articles in collaboration, 3 oral presentations, 12 communications with 1 awarded (EMBO travel grant)



INRA UMR1198 Biologie du Développement et Reproduction

• Modeling of the morphogenesis of an embryonic epithelium with trophic function: the trophoblast

  • Apr 2007 - Sep 2008

  Jouy-en-Josas, France Funding: Région Ile-de-France/INRA Methods: immunohistology, immunofluorescence, confocal microscopy, interpretation of results with mathematicians Publications: 4 original articles, 4 articles in collaboration, 7 communications



USDA Animal Biosciences and Biotechnology Laboratory

• Proteomics and related functional genomics analyses of porcine embryos

  • Feb 2006 - Mar 2007

  Beltsville, MD, USA Funding : USDA Visiting Scientist Fellowship Methods : Development of 2D proteomics tools Publications: 1 original article, 2 communications with 1 awarded (Keystone symposium)

• phD : Functional genomics study of normal and cloned bovine embryos

  • Sep 2001 - Jan 2006

  Jouy-en-Josas, France Project : Study on the growth and differentiation of the trophoblast in early pregnant mammals: Functional genomics study of normal and cloned bovine embryos Funding : MENRT + CDD INRA Methods : Development of transcriptomics tools (bovine microarrays, bioinformatics & statistical tools) Publications: 6 original articles, 6 articles in collaboration, 3 oral presentations, 18 communications, 1 travel grant to attend an international congress [Jean et Marie-Louise Dufrenoy / Académie de… Show more Project : Study on the growth and differentiation of the trophoblast in early pregnant mammals: Functional genomics study of normal and cloned bovine embryos Funding : MENRT + CDD INRA Methods : Development of transcriptomics tools (bovine microarrays, bioinformatics & statistical tools) Publications: 6 original articles, 6 articles in collaboration, 3 oral presentations, 18 communications, 1 travel grant to attend an international congress [Jean et Marie-Louise Dufrenoy / Académie de l’Agriculture] Show less