Experience

Cancer Science Institute of Singapore

• Singapore
• Research Services
• 1 - 100 Employee

• Research Fellow

  • Mar 2022 - Present

  My current research is to characterize the functional roles of H3K27me3-associated loops in Acute Myeloid Leukemia. My current research is to characterize the functional roles of H3K27me3-associated loops in Acute Myeloid Leukemia.



University of Liège

• Belgium
• Higher Education
• 700 & Above Employee

• Postdoctoral Research Associate

  • Nov 2015 - Feb 2022

  University of Liege, Liege, Belgium (group of Prof. Dr. Alain Chariot) • Investigating the molecular mechanism by which Constitutive Photomorphogenic 1 regulates estrogen receptor-α transcription in breast cancer • Extensive experience in molecular biology, including bacterial plasmid subcloning, western blot, qRT-PCR, lentiviral vector-mediated gene knockdown, co-immunoprecipitation, chromatin immunoprecipitation • Collaborate with researchers from University Hospital Cologne for human breast cancer tissue microarray Show less



Radboudumc

• Netherlands
• Hospitals and Health Care
• 700 & Above Employee

• Postdoctoral Research Associate

  • Nov 2013 - Mar 2015

  Radboud University, Nijmegen, The Netherlands (group of Prof. Dr. Peter Deen) • The aims of this study were to determine the renal targeting and knockdown efficiency of TRPC6 and AQP2 and to validate TRPC6 as a therapeutic target in proteinuria using siRNA-microbubbles technology • Skilled in co-administration of intravenous microbubbles and siRNA in mice and performed ultrasound-mediated microbubble destruction to enhance cellular uptake of siRNA in mouse kidney • Worked in collaboration with three researchers from Erasmus University Rotterdam, University of Twente and RWTH Aachen University for their technical support in handling ultrasound device and microbubbles Show less



The Netherlands Cancer Institute

• Netherlands
• Research Services
• 400 - 500 Employee

• PHD

  • Apr 2009 - Jul 2013

  The Netherlands Cancer Institute, Amsterdam, The Netherlands (group of Dr. Alfred Schinkel) • My doctoral dissertation focused on the role of apical ATP-binding cassette transporters (ABCB1 and ABCG2) in plasma pharmacokinetics and brain disposition of several tyrosine kinase inhibitors and everolimus using in vitro and in vivo models • Expertise in transepithelial permeability assay, in vitro drug metabolic study using liver microsomes • Familiar with animal handling techniques and the utilization of animal models for pharmacokinetic study • Initiated and led collaborations involving two researchers from Leiden University Medical Center and Kanazawa University for experiments involving Ces1c knockdown in mice and hydrolysis activity of everolimus by recombinant human carboxylesterase enzymes • Presented research findings in three conferences and seminars • Performed data analysis and prepared manuscripts for publication Show less



Universiti Putra Malaysia

• Malaysia
• Higher Education
• 700 & Above Employee

• Research Assistant

  • May 2004 - May 2005

  University Putra Malaysia, Selangor, Malaysia (group of Prof. Dr. Johnson Stanslas) • Evaluated the potential in vitro and in vivo anticancer effects of 35 water-based plant extracts provided by Autoimmune Sdn Bhd • Assessed the hepatoprotective effect of Hepat, a herbal-based product by Autoimmune Sdn Bhd in rats • Experienced in mammalian cell culture, conducted statistical analysis and prepared written reports for client University Putra Malaysia, Selangor, Malaysia (group of Prof. Dr. Johnson Stanslas) • Evaluated the potential in vitro and in vivo anticancer effects of 35 water-based plant extracts provided by Autoimmune Sdn Bhd • Assessed the hepatoprotective effect of Hepat, a herbal-based product by Autoimmune Sdn Bhd in rats • Experienced in mammalian cell culture, conducted statistical analysis and prepared written reports for client