Experience

Pharmaron

• China
• Pharmaceutical Manufacturing
• 700 & Above Employee

• Senior Director Pharmaceutical Metabolism

  • May 2022 - Present



GSK

• United Kingdom
• Pharmaceutical Manufacturing
• 700 & Above Employee

• Senior Director, Head of Bioanalysis and Biomarjers (UK), GLP Operator

  • Dec 2017 - Present

• Senior Director

  • Oct 2014 - Mar 2020

  Nov 2019 - present: UK Head of Biomarkers and Bioanalysis (supporting small molecule TK, PK and biomarker bioanalysis (LC-MS/MS), large molecule PK and biomarker (LBA, Western blot), protein MS for PK and biometabolism, outsourcing of late phase trials and TK).Dec 2015 - Oct 2019: WW Head of small and large molecule bioanalysis

• Director

  • Apr 2009 - Nov 2015

  2009 - 2015: Site Head for small and large molecule bioanalysis (non-GLP TK, GLP TK, Clinical PK)2012 - 2014: Also Head of Biopharm Bioanalysis at Upper Merion site, PA, US2010 - 2015: DMPK Portfolio Liaison for Biopharm Projects or Neuroscience

• Director WW (Biopharm Bioanalysis)

  • Jan 2012 - Dec 2013

• Section Leader, Bioanalysis (DMPK)

  • Jul 2008 - Apr 2009

  Overseeing small molecule regulated bioanalysis of several teams (non-GLP, GLP TK and clinical PK)

• Section Leader

  • Jun 2008 - Mar 2009

• Bioanalyst (Neurology DMPK)

  • Mar 2001 - Jul 2008

  1. Team Leader of LC-MS analytics (small molecule PK, metabolite id, in vitro ADME assays such as intrinsic clearance and brain tissue binding.2. Discovery DMPK rep for lead optimisation projects up to candidate selection.3. Led in vivo workstream research effort trying to understand the key factors for successful CNS drugs (published multiple papers on brain tissue binding, CNS penetration, Kpuu)



Drug Metabolism Discussion Group (European)

• Committee Member

  • Jun 2008 - Nov 2013

  Treasurer (3 yr), Secretary (1 yr), Chairman (1 yr) - Organising DMPK courses and Conferences for Industry partners. Introduced Biopharm courses and Symposia into annual curriculum

• Tutor (Fundamentals of DMPK Course)

  • Apr 2000 - Apr 2011



SMITHKLINE BEECHAM RESEARCH LIMITED

• United Kingdom

• Bioanalyst

  • Sep 1997 - Mar 2001