Scott Kimber
Research And Development Manager at Camallergy- Claim this Profile
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Bio
Experience
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Camallergy
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United Kingdom
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Pharmaceutical Manufacturing
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1 - 100 Employee
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Research And Development Manager
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Oct 2022 - Present
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Novacyt
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United Kingdom
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Biotechnology
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1 - 100 Employee
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Principal Scientist
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Jan 2021 - Sep 2022
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University of Southampton
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United Kingdom
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Higher Education
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700 & Above Employee
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Postdoctoral Research Fellow
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Jan 2019 - Jan 2021
PIP5K is an lipid kinase that generates the phosphoinositide messenger PIP2. Canonically this lipid is hydrolysed by phospholipase C (PLC) to two new second messengers IP3, which regulates calcium and DAG which regulates PKC. In the nucleus besides being a substrate for PLC, PIP2 also directly regulates gene transcription and mRNA maturation by interacting with and regulating target proteins. We have identified a protein that interacts with PIP5K that is involved in regulating histone modifications and consequently transcription. We are trying to understand exactly how PIP5K and its product PIP2 impacts on the activity of this histone modifying complex and how this then regulates gene transcriptional output.
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The Institute of Cancer Research
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United Kingdom
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Research
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700 & Above Employee
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Postdoctoral Researcher
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Nov 2015 - Nov 2018
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University of Southampton
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United Kingdom
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Higher Education
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700 & Above Employee
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Postdoctoral Research Fellow
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Oct 2014 - Oct 2015
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Education
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University of Southampton
Doctor of Philosophy - PhD, Biochemistry -
University of Southampton
Bachelor of Science - BS, Biochemistry