Experience

Crystal Pharmatech

• United States
• Pharmaceutical Manufacturing
• 1 - 100 Employee

• Senior Scientist II

  • Dec 2022 - Present

• Senior Scientist I

  • Oct 2021 - Jan 2023

  Work with clients on polymorph/salt screening and form selection, crystallization process development and scale-up, analytical chemistry, pre-formulation work including pKa determination, solubility and physical/chemical stability assessment, excipient compatibility, force degradation, formulation stability, spray drying and scale-up. Use scientific and statistical analysis to develop process understanding and conduct root cause analysis. Lead a group of scientists and provide technical support as necessary. Act as SME on HPLC method development and optimization. Show less

• Research Scientist II

  • Feb 2020 - Sep 2021

  Focus on early formulation development including polymorph and salt screening, phase investigation, phase selection, crystallization method development and scale-up.



Celgene

• United States
• Pharmaceutical Manufacturing
• 700 & Above Employee

• Scientist I (Drug Product Development)

  • Mar 2019 - Jan 2020

  Develop and validate an in-vitro permeation model for poorly soluble, high molecular weight compounds. Design and develop formulations including nano-suspensions, amorphous solid dispersions, lipid based systems etc. on bench scale and assess product performance using characterization tools such as µFLUX™, HPLC, FTIR, MDSC, PXRD, SEM, Particle size analysis, etc. Maintain electronic lab notebook. Present scientific findings to the team on a weekly basis. Develop and validate an in-vitro permeation model for poorly soluble, high molecular weight compounds. Design and develop formulations including nano-suspensions, amorphous solid dispersions, lipid based systems etc. on bench scale and assess product performance using characterization tools such as µFLUX™, HPLC, FTIR, MDSC, PXRD, SEM, Particle size analysis, etc. Maintain electronic lab notebook. Present scientific findings to the team on a weekly basis.



GSK

• United Kingdom
• Pharmaceutical Manufacturing
• 700 & Above Employee

• R&D Biopharmaceuticals Co-op (Advanced Manufacturing Technology)

  • Sep 2015 - Aug 2016

  Assisted in development of large molecule formulations, identified critical process parameters and used design of experiment (JMP software) for parameter screening and optimization. Used spray drying equipment on bench scale as well as pilot scale. Assessed long term and short term stability of the developed formulations. Analytical tools such as FTIR, MDSC, SEM, UV-280, Karl Fisher analysis, Size Exclusion Chromatography etc. were used to determine product performance and behavior at every stability time point. Investigated and identified root cause of stability issues based on the formulation aspects and molecular degradation pathways. Worked with new technological platforms for drug product stabilization. Show less