Experience

Institute Of Microbial Technology

• Biotechnology
• 100 - 200 Employee

• PI

  • Mar 2001 - Present

  With my experience in two different fields (pseudo uridine synthase and ocular gene therapy), I started my independent career in the field of molecular microbiology. Initially, I was studying the interaction of Vibrio cholerae with E. histolytica. Though we published one paper in J Med Micro, the project did n't go further. While pursuing, I came across the world of biofilm and quorum sensing which has become a primary focus of my lab. We are exploiting natural QS mutants to screen small molecule inhibitiors. Other than qs, I am also interested in model systems to understand bacterial pathogenesis and host response upon infection. In this connection, we have developed a yeast model to understand the function of bacterial virulence factors having eukaryotic domains. This yeast model is very useful to screen chemical libraries. Publications J Med Micro 1995; RNA, 1998: J Biol Chem 1999, RNA 2001; Agent Chem 2002; Emerg Infect Dis 2003; Gene 2006; Mol Therapy 2007, J Med Micro 2006; J Med Micro 2008; J Med Micro 2010; Env Micro Rep 2010; J Med Micro 2011; J Biol Chem 2011;Biol Direct 2012; Gene 2013; PLOS One 2013;Gut Pathogen 2013, Mol Gen Genom (MGG) 2014; PLOS One 2014;Plos One 2015; Microbial Cell Factory 2016; Show less



University of Miami, FL and Texas Childrens' hospital, TX, USA

• Post doc 1997-1999, 1999-2000, 2008

  • 1997 - 2000

  Did post doc with Late Prof. James Ofengand (Jim) in the field of ribosomology / pseudouridine synthases of E.coli. Published three papers in RNA (2) and JBiol Chem. My second post doc was with Dr. Richard L Hurwitz, TMC, BCM, TX. There I worked in the field of ocular gene therapy. Published one paper in Molecular Therapy. As a visiting fellow, I spent two months in 2008 with Prof. Guannar Sandstrom group in SMI, Karolinska, Sweden Did post doc with Late Prof. James Ofengand (Jim) in the field of ribosomology / pseudouridine synthases of E.coli. Published three papers in RNA (2) and JBiol Chem. My second post doc was with Dr. Richard L Hurwitz, TMC, BCM, TX. There I worked in the field of ocular gene therapy. Published one paper in Molecular Therapy. As a visiting fellow, I spent two months in 2008 with Prof. Guannar Sandstrom group in SMI, Karolinska, Sweden