Sapana Kushwaha
Assistant Professor at National Institute of Pharmaceutical Education and Research Raebareli- Claim this Profile
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Bio
Experience
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National Institute of Pharmaceutical Education and Research Raebareli
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India
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Research Services
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1 - 100 Employee
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Assistant Professor
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Aug 2021 - Present
Raebareli, Uttar Pradesh, India Working in the Department of Pharmacology and Toxicology, NIPER-Raebareli.
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Babasaheb Bhimrao Ambedkar University Lucknow
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India
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Higher Education
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1 - 100 Employee
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Assistant Professor
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Nov 2017 - Aug 2021
Lucknow Area, India Pharmaceutical Sciences
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DBT-RAJIV GANDHI CENTRE FOR BIOTECHNOLOGY
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India
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Research
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1 - 100 Employee
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Toxicologist
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Oct 2017 - Nov 2017
New Delhi, Delhi, India "Biosafety Support Unit (BSU)”is funded by the Department of Biotechnology, Govt. of India and functions in New Delhi to assist in scrutiny of applications received for risk assessment and prepares reports to facilitate decision making by the Competent Bodies. I was working as a Scientist (Toxicology) in Biosafety Support Unit (BSU), New Delhi.
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Central Drug Research Institute, Lucknow
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Pharmaceutical Manufacturing
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300 - 400 Employee
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CSIR Nehru Postdoctoral Fellow
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Oct 2014 - Sep 2017
LUCKNOW I was working as Post Doctoral Fellow with Dr Sabyasachi Sanyal, Principal Scientist, Central Drug Research Institute (CDRI), Lucknow, India. My research project was mainly focused on muscle biology.
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Senior Project Fellow
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Dec 2013 - Sep 2014
Lucknow Area, India I was working with Dr Sabyasachi Sanyal, Principal Scientist, Central Drug Research Institute (CDRI), Lucknow, India. My work was mainly focused on muscle biology.
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National Institute of Pharmaceutical Education and Research (NIPER) ,SAS NAGAR , Mohali
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India
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Education Administration Programs
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100 - 200 Employee
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Graduate Student
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Jul 2009 - Dec 2013
Mohali I have done Ph.D these years with Professor G.B. Jena. My Ph. D project work was entitled "Chemical Susceptibility in Hyperglycemic Condition: Study with Selected Antihypertensive Drugs in Streptozotocin (STZ)-Induced Diabetic Rat Model" This work is mainly focused on deciphering different targets and molecular pathways to understand the mechanisms of selected anti-hypertensive drugs in rat with diabetes and exacerbation by toxic insults, such as nicotine. This doctoral work provides new… Show more I have done Ph.D these years with Professor G.B. Jena. My Ph. D project work was entitled "Chemical Susceptibility in Hyperglycemic Condition: Study with Selected Antihypertensive Drugs in Streptozotocin (STZ)-Induced Diabetic Rat Model" This work is mainly focused on deciphering different targets and molecular pathways to understand the mechanisms of selected anti-hypertensive drugs in rat with diabetes and exacerbation by toxic insults, such as nicotine. This doctoral work provides new insights into the mechanisms of protection by the intervention with selected antihypertensive drugs under hyperglycemic conditions. Further, the investigation also provides an opportunity to explore different molecular targets in the induction as well as amelioration of toxic insults in diabetic animals. In addition to these findings, we had reported that in diabetic condition, oxidatively damaged DNA in peripheral blood lymphocytes exhibits positive correlation with that of other tissues and may serve as a surrogate biomarker for oxidatively damaged DNA in the internal organs. Findings and most of these have been published in peer-reviewed journals such as Mutation research, Journal of applied toxicology, and Human and Experimental Toxicology.
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Postgraduate Student
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Jul 2007 - Jun 2009
India I was lucky to be the first M. S. (Pharm) student in the discipline of Regulatory Toxicology, a new course introduced for the first time in INDIA, at NIPER Mohali in the year 2007. I worked under the guidance of Professor G. B. Jena, NIPER, Mohali. My master project entitled “Evaluation of methotrexate toxicity in neonate, juvenile and adult mice: A regulatory Consideration”. It was mainly focused on the integration of genotoxicity tests using comet and micronucleus assay in 28 days of… Show more I was lucky to be the first M. S. (Pharm) student in the discipline of Regulatory Toxicology, a new course introduced for the first time in INDIA, at NIPER Mohali in the year 2007. I worked under the guidance of Professor G. B. Jena, NIPER, Mohali. My master project entitled “Evaluation of methotrexate toxicity in neonate, juvenile and adult mice: A regulatory Consideration”. It was mainly focused on the integration of genotoxicity tests using comet and micronucleus assay in 28 days of repeated-dose oral toxicity tests. Findings of that work showed that genotoxicity assays (micronuclei and comet) can be successfully integrated into the routine toxicity test for regulatory compliance. The outcome of my M.S. work has been published in form of a research paper entitled ‘Evaluation of multi-organ DNA damage by comet assay from 28 days repeated dose oral toxicity test in mice: A practical approach for test integration in regulatory toxicity testing’ in Journal, Regulatory Toxicology and Pharmacology, 2010. This work has been cited in “Organization for Economic Co-operation and Development (OECD) Guideline for The Testing of Chemicals, In vivo Mammalian alkaline comet assay and Rodent alkaline single cell gel electrophoresis assay (OECD GUIDELINE 489).
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Education
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National Institute of Pharmaceutical Education and Research (NIPER) ,SAS NAGAR , Mohali
Doctor of Philosophy - PhD, Pharmacology and Toxicology -
National Institute of Pharmaceutical Education and Research (NIPER) ,SAS NAGAR , Mohali
M.S (Pharm), Regulatory Toxicology -
BBD University
Bachelor of Pharmacy (B.Pharm.) -
Jawahar Navodaya Vidyalaya (JNV)
Science