Experience

Philochem AG

• Switzerland
• Research Services
• 1 - 100 Employee

• Head of Small Molecule Therapeutics

  • Jan 2019 - Present

  • Lead innovative projects aiming at developing new drugs based on small ligands for the active delivery of radioactive and cytotoxic payloads to tumors • Hire, guide and motivate team members as direct line manager by determining goals and priorities and managing individual performance • Conceive new product ideas for the initiation of new research projects • Lead the "Small Molecule Therapeutics" research team from identification of hit compounds to the lead definition by designing… Show more • Lead innovative projects aiming at developing new drugs based on small ligands for the active delivery of radioactive and cytotoxic payloads to tumors • Hire, guide and motivate team members as direct line manager by determining goals and priorities and managing individual performance • Conceive new product ideas for the initiation of new research projects • Lead the "Small Molecule Therapeutics" research team from identification of hit compounds to the lead definition by designing and supervising both in vitro and in vivo strategy • Establish and follow up collaborations with CROs, CMOs, academic laboratories and KOLs • Present scientific projects internally and externally at international scientific conferences • Work closely with the IP department for filing patents • Support translational studies aiming to i) select first-in-human (FIH) doses and ii) support the clinical development of the compounds • Support toxicology in rodents and other species • Support business development team • Work together with the medical doctors to define clinical development plans • Deep understanding of tumor targeting with small molecules, peptides and antibodies, tumor microenvironment and tumor immunology

• Research Scientist

  • Feb 2018 - Jan 2019

  • Design and perform key experiments for the development of pipeline compounds and for external collaborations • Support IP department for filing patents



ETH Zürich

• Switzerland
• Higher Education
• 700 & Above Employee

• Doctoral Student

  • Jan 2015 - Jan 2018

  Zürich Area, Switzerland Doctoral student in the group of Prof. Dario Neri, Institute of Pharmaceutical Sciences (IPW) PhD Thesis on "Drug Conjugates Specific to Carbonic Anhydrase IX for Cancer Therapy" In my PhD, I have focused on synthesis and biological (in vitro and in vivo) evaluation of non-internalizing Small Molecules-Drug Conjugates, Antibody-Drug Conjugates and Small Molecules-Radio Conjugates targeting CAIX in tumors



Università degli Studi di Milano

• Higher Education
• 700 & Above Employee

• MSc Student - Dept. of Pharmaceutical Sciences

  • Sep 2013 - Oct 2014

  Milan, Italy Medicinal Chemistry - Group of Prof. Carlo De Micheli Thesis on "Biocatalysis in flow chemistry reactors: an innovative approach for the production of fructooligosaccharides"