Ryan Manning
Senior Research Engineer at Quanterix- Claim this Profile
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Experience
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Quanterix
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United States
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Biotechnology Research
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200 - 300 Employee
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Senior Research Engineer
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Apr 2021 - Present
Billerica, Massachusetts, United States • Contributed to the invention and definition of next generation Simoa technologies • Lead the hands-on demonstrations of feasibility research and invention of novel Simoa technologies, including advanced miniaturization technologies, novel optical systems, system software, and consumables • Developed research-level system software to enable breadboard and prototype development • Tested platform design, system integration and verification pertaining to the miniaturization… Show more • Contributed to the invention and definition of next generation Simoa technologies • Lead the hands-on demonstrations of feasibility research and invention of novel Simoa technologies, including advanced miniaturization technologies, novel optical systems, system software, and consumables • Developed research-level system software to enable breadboard and prototype development • Tested platform design, system integration and verification pertaining to the miniaturization approaches • Lead collaborations with technology development partners to develop and evaluated new technologies on systems and consumables • Lead collaborations with assay scientists in the Technology group to demonstrate Simoa assays on novel prototype platforms • Drove linkages between the engineering and assay development groups to transfer new Simoa technologies from feasibility to full development Show less
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MilliporeSigma
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United States
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Biotechnology Research
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700 & Above Employee
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Product Development Engineer III
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May 2018 - Apr 2021
Burlington, Massachusetts, United States ● Designe, developed and tested new products and processes from concept to commercialization. ● Technical lead that drove new products through the stage gate process. ● Worked closely with an interdisciplinary team to develop and launch innovative products that address customer needs. ● Performed prototyping, test and verification activities, as well as validation activities in coordination with the receiving manufacturing plant during the product commercialization phase. ●… Show more ● Designe, developed and tested new products and processes from concept to commercialization. ● Technical lead that drove new products through the stage gate process. ● Worked closely with an interdisciplinary team to develop and launch innovative products that address customer needs. ● Performed prototyping, test and verification activities, as well as validation activities in coordination with the receiving manufacturing plant during the product commercialization phase. ● Utilized statistical methods to evaluate the capability and reliability of experimental results. Show less
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ProteinSimple
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United States
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Biotechnology Research
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100 - 200 Employee
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Engineer
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Sep 2016 - May 2018
Wallingford, Connecticut Designed an automated system to dispense biological reagents into an OEM microfluidic cartridge o Used statistical analysis to prove that there was no difference in assay performance between using the manual dispense systems and the automated system. ● Developed a staged inspection system to increase throughput and quality control of OEM cartridges. o Automation replaced a process that was previously manual. ● Invented a new method to deactivate PDMS to increase production… Show more Designed an automated system to dispense biological reagents into an OEM microfluidic cartridge o Used statistical analysis to prove that there was no difference in assay performance between using the manual dispense systems and the automated system. ● Developed a staged inspection system to increase throughput and quality control of OEM cartridges. o Automation replaced a process that was previously manual. ● Invented a new method to deactivate PDMS to increase production capacity and product reliability. o Developed test fixtures, performed fundamental process verification and accelerated life tests. ● Developed a manufacturing scaling plan to increase manufacturing capacity while minimizing capital expenditure and company overhead. o Optimization of manufacturing work flow and expansion plans for manufacturing floorspace.
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Design Transfer/Quality Engineer
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Jul 2014 - Sep 2016
Wallingford, Connecticut Designed experiments to test in-house manufacturing processes and individual components for tolerances based on engineering drawings. ● Utilized SolidWorks to design parts and develop drawing packages used in various projects. o Including: Ella instrument calibration, immunoassay validation, reagent dispensing o Improved instrument setup repeatability and decreased calibration time by designing parts that allowed for less manual processes. ● Designed, assembled, and wrote… Show more Designed experiments to test in-house manufacturing processes and individual components for tolerances based on engineering drawings. ● Utilized SolidWorks to design parts and develop drawing packages used in various projects. o Including: Ella instrument calibration, immunoassay validation, reagent dispensing o Improved instrument setup repeatability and decreased calibration time by designing parts that allowed for less manual processes. ● Designed, assembled, and wrote software for a dry-box monitoring system utilizing NI hardware and LabVIEW.
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CyVek
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Spain
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Computers and Electronics Manufacturing
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Associate Engineer
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Jul 2012 - Jun 2014
Wallingford, Connecticut Experience with due diligence, IP review, and sale of CyVek Inc. to Bio-Techne. o Bio-Techne purchased CyVek Inc. for $95 million in 2014. ● Part of the R&D team tasked with determining upstream causes of variance in immunoassay results. o Tested design changes and reported qualitative and quantitative results. ● Lead quality control efforts for various parts used in the manufacturing of our custom microfluidic cartridge.
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Engineering Intern
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Jun 2010 - Jan 2011
Wallingford, Connecticut ● Helped develop image and data analysis software using LabView and National Instruments hardware. ● Ran Elisa microfluidic immunoassays and analyzed resulting data with LabView developed software. ● Developed designs in AutoCAD for use in photolithography.
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Education
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The University of Connecticut
Biomedical Engineering Major, Engineering -
The University of Connecticut
Computer Science Engineering Minor, Engineering