Rylee Poole
Laboratory Research Assistant at Indiana University Melvin and Bren Simon Comprehensive Cancer Center- Claim this Profile
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Bio
Experience
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IU Simon Comprehensive Cancer Center
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United States
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Research Services
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1 - 100 Employee
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Laboratory Research Assistant
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Jun 2022 - Present
The Opyrchal Lab focuses on identifying key players in the immune response to triple negative breast cancer, and how these can be harnessed to develop novel therapeutics and improve the efficacy of immunotherapies against this aggressive cancer type. The Opyrchal Lab focuses on identifying key players in the immune response to triple negative breast cancer, and how these can be harnessed to develop novel therapeutics and improve the efficacy of immunotherapies against this aggressive cancer type.
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Purdue University
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United States
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Higher Education
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700 & Above Employee
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Undergraduate Research Assistant - Chang Laboratory
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Aug 2020 - Jun 2022
Work conducted includes: Determining the developmental time frame for the PR2 gene, whose homolog is implicated in human cancer metastasis, in Drosophila through temperature-sensitive knockout. Using ImageJ to examine ommatidia stress-fiber lengths in wild-type vs mutant vkg loci. Examining the neural degeneration of photoreceptors in IP3R- Drosophila over time through luciferase assays, studying the ommatidium grommet size in the presence and absence of IP3R and sevenless mutations, and identifying gene expression patterns in the wing discs and eye discs of Drosophila by means of GFP detection, lacZ assays, and antibody staining. Utilizing a forwards genetic approach on Drosophila melanogaster to investigate the downstream effects of the PR2 and ACK1 kinases, and determining how a knockout mutation in PR2 plays a role in the sterility of female flies. Show less
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Biology Resource Center Tutor and Course Liaison
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Sep 2021 - May 2022
Tutored undergraduate students in complex biological concepts to improve overall student success in biology courses. Maintained excellent communication with biological sciences professors and staff to navigate particularly difficult topics and ensure maximal student comprehension.
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Teacher Assistant
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Jan 2021 - Jan 2022
My roles in these laboratories are to communicate the importance of each laboratory procedure, ensure laboratory safety, clearly answer questions of 25 students, handle and distribute chemical reagents, and grade assignments for undergraduate molecular, cellular, and genetics laboratories.
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Self Employed
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United States
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700 & Above Employee
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Nanny
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May 2020 - Aug 2020
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Purdue University
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United States
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Higher Education
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700 & Above Employee
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Boiler Gold Rush Team Leader
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Mar 2019 - Aug 2019
Demonstrated effective leadership and communication leading a group of 15 incoming college students around a large and complex orientation program. Welcomed over 7,000 new students, domestic and international, with an inclusive mind and open heart to help everyone feel at home during their transition to the university. Exhibited the ability to work under pressure when crises arose among the new students and other orientation leaders. Demonstrated effective leadership and communication leading a group of 15 incoming college students around a large and complex orientation program. Welcomed over 7,000 new students, domestic and international, with an inclusive mind and open heart to help everyone feel at home during their transition to the university. Exhibited the ability to work under pressure when crises arose among the new students and other orientation leaders.
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Administrative Secretary
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Aug 2017 - Jun 2018
Managed inventory, organized payments, arranged fundraisers, and created monthly newsletters to keep the studio running smoothly and ensure that parents and students were up to date on important issues. Managed inventory, organized payments, arranged fundraisers, and created monthly newsletters to keep the studio running smoothly and ensure that parents and students were up to date on important issues.
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Education
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Purdue University
Bachelor of Science - BS, Biology, General