Roxana Andreea Moldovan

Bioinformatics Technician at INCLIVA Instituto de Investigación Sanitaria
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Contact Information
Location
Valencia, Valencian Community, Spain, ES
Languages
  • Español Native or bilingual proficiency
  • Rumano Native or bilingual proficiency
  • Frances Limited working proficiency
  • Inglés Full professional proficiency

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Credentials

  • Supervised Machine Learning: Regression and Classification
    Coursera
    Feb, 2023
    - Sep, 2024
  • Asistencia a la IX Trobada de jóvens investigadores
    Universitat de València
    May, 2022
    - Sep, 2024
  • Fundamentos de big data
    LinkedIn
    Sep, 2021
    - Sep, 2024
  • English B2 (Cambridge English Level 1 Certificate in ESOL International First)
    Cambridge Assessment English
  • Mención en Biomedicina
    Universidad de Castilla-La Mancha

Experience

    • Spain
    • Research Services
    • 100 - 200 Employee
    • Bioinformatics Technician
      • Apr 2023 - Present

      Contributing to the Bioinformatics Unit, including: - Implementing and maintaining software for sample management and omics data analysis, covering processes such as Variant Calling or Single-Cell analysis. - Streamlining, managing, and optimizing omics data analysis workflows using Nextflow and nf-core for execution on HPC clusters with Slurm queuing system. - Conducting comprehensive benchmark analyses on a range of methodologies and tools. This initiative aims to refine and elevate the precision of variant calling by optimizing specificity, sensitivity, and minimizing noise. Show less

    • Spain
    • Research Services
    • 100 - 200 Employee
    • Estudiante en prácticas
      • Jan 2023 - Sep 2023

      Master's Thesis "Transcriptomic landscape of sex differences in obesity and type 2 diabetes" at the Computational Biomedicine Lab. The clinical and epidemiological sex differences in obesity and diabetes 2 have been widely described. However, the underlying molecular mechanisms remain poorly understood. In this meta-analysis, we aimed to identify transcriptomic biomarkers that can provide insights into sex differences in these conditions. To this end, a 3-steps strategy was carry out: a) A systematic review of transcriptomic studies in the public repositories GEO and BioStudies. b) The download and bioinformatic analysis of each dataset. c) Their subsequent integration using meta-analysis techniques and functional characterization. First results identified biomarkers that may be useful in the development of personalized medicine in obesity and diabetes 2, including the sex information. Show less

    • Spain
    • Biotechnology Research
    • 1 - 100 Employee
    • Bioinformática
      • Jul 2022 - Jan 2023

      Bioinformatician. Among the primary tasks undertaken, I have engaged in: - Development of code and graphical applications using R and Shiny within the framework of the 'SAMBA: Structure-Learning of Aquaculture Microbiomes Using a Bayesian-Network Approach' project (doi: https://doi.org/10.3390/genes14081650, https://github.com/biotechvana/samba). - Creation of pipelines and bioinformatic analyses for RNA-seq data. - Active involvement in the graphic design, programming, and coordination of an E-Learning platform. - Classification of RSV viruses based on their genomic information. Show less

    • Estudiante en prácticas de bioinformática
      • Oct 2021 - Jun 2022

      Bioinformatics intern in the Evolutionary Genetics department at I2SysBio. Key responsibilities and accomplishments include: - Conducting phylogenetic analysis. - Preprocessing and assembly of sequences obtained through third-generation sequencing techniques (PacBio). - Structural and functional annotation, as well as alignment of prokaryotic genomes using automated software and subsequent manual curation. - Development of Python and Bash pipelines for the annotation of repeated sequences. Software and tools utilized: MEGA X, Staden Package, Artemis Software (ACT and ART), Prokka, RepeatModeler, RepeatMasker, RMBlast, Decypher, Dfam, Gene Ontology, NCBI, BLAST, among others. Show less

    • Estudiante en prácticas
      • Aug 2020 - Sep 2020

      Among the tasks performed during my internship, I engaged in: - Reception, processing, and categorization of samples. - Routine analysis on blood, urine, and fecal samples, involving biochemical and immunological tests, cultures, and microscopic observation. - Handling, calibration, and preparation of standards and controls for automated analyzers. - Fertility testing, conducting a semen analysis that includes seeding, characterization, and microscopic observation of sperm to perform a count and assess viability, morphology, and sperm motility." Show less

Education

  • Universitat de València
    Máster en Bioinformática, Bioinformática
    2021 - 2023
  • Universidad de Castilla-La Mancha
    Grado en Bioquímica, Bioquímica
    2017 - 2021

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