Experience

Mediar Therapeutics
• United States
• Biotechnology Research
• 1 - 100 Employee
• Director, Translational Medicine

  • Jun 2023 - Present

Scholar Rock
• United States
• Biotechnology
• 1 - 100 Employee
• Associate Director, Discovery Biology

  • Apr 2022 - May 2023


Takeda

• Biotechnology
• 1 - 100 Employee

• Principal Scientist

  • Mar 2021 - Apr 2022

• Senior Scientist

  • Apr 2019 - Feb 2021



Pliant Therapeutics

• United States
• Biotechnology Research
• 1 - 100 Employee

• Scientist II

  • Apr 2018 - Apr 2019

  -Designing in vitro and in vivo (mouse) models to enable target validation, and lead optimization and selection of small molecule therapeutics or biologics for various fibrotic indications and cancer immunotherapy -Serving on a cross-functional project teams with chemistry, DMPK, and HTS experts -Initiating and overseeing external CRO studies -Designing in vitro and in vivo (mouse) models to enable target validation, and lead optimization and selection of small molecule therapeutics or biologics for various fibrotic indications and cancer immunotherapy -Serving on a cross-functional project teams with chemistry, DMPK, and HTS experts -Initiating and overseeing external CRO studies



Gilead Sciences

• United States
• Biotechnology Research
• 700 & Above Employee

• Research Scientist, Fibrosis Biology

  • Feb 2016 - Apr 2018

  -Developed primary hepatocyte and stellate cell-based assays to evaluate drug disposition and MOA of a clinical-stage and exploratory small molecule therapeutic for NASH -Initiated and managed multiple academic collaborations and external CRO studies -Served on cross-functional project teams for a exploratory NASH target -Developed primary hepatocyte and stellate cell-based assays to evaluate drug disposition and MOA of a clinical-stage and exploratory small molecule therapeutic for NASH -Initiated and managed multiple academic collaborations and external CRO studies -Served on cross-functional project teams for a exploratory NASH target


Clontech
• United States
• Chemical Manufacturing
• Marketing Specialist I

  • Mar 2015 - Jan 2016


Harvard Medical School

• United States
• Higher Education
• 700 & Above Employee

• Postdoctoral Fellow

  • Aug 2012 - Jan 2015

  Project #1: Strategies to improve regeneration of skeletal muscle by targeting muscle stem cell function -This project involves in-depth collaboration with a large pharmaceutical company. Interactions involve monthly conference calls, semi-annual progress presentations, exchange of protocols and presentation of findings at annual scientific conferences. -Used RNA sequencing of muscle-resident mesenchymal stromal cells to identify novel interactions with muscle stem cells. -Validated select growth factors by qRT-PCR arrays and ELISA. -Evaluated the positive effect of select growth factors on proliferation of mouse and human muscle stem cells in vitro.Currently evaluating efficacy in vivo after muscle injury. Project #2: Novel strategies to treat rhabdomyosarcoma (pediatric muscle cancer) -Collaboration: Dr. Brent Stockwell Columbia University. -Evaluated efficacy of Ferroptosis (Iron-dependent cell death via activation of Reactive Oxygen Species [ROS]) as a means to selectively eliminate sarcoma cells, in a novel preclinical murine model of rhabdomyosarcoma. Show less



University of Pittsburgh

• United States
• Higher Education
• 700 & Above Employee

• Graduate Student Researcher.

  • Jan 2006 - Jul 2012

  Isolation and characterization of stem cells from mouse and human gallbladders and liver. -Used colony forming and single cells assays to identify cell surface markers for resident stem cells in the adult mouse gallbladder and liver and fetal human gallbladder. -Evaluated engraftment of mouse and human gallbladder stem cells in a mouse model in vivo. -Used oligonucleotide microarrays to investigate difference between gallbladder and intrahepatic bile duct cells. Differentation of gallbladder stem cells into insulin producing cells. Collaboration with Dr. Ipsita Bannerjee (University of Pittsburgh). · Ongoing efforts to differentiate mouse gallbladder stem cells into insulin-producing cells and engraft cells into streptozotocin-treated mice. These projects resulted in 5 first-author publications including a book chapter, and 1 middle author publication Show less



Denison University

• United States
• Higher Education
• 700 & Above Employee

• Undergraduate Student Researcher.

  • Sep 2002 - Apr 2006

  Investigating Neurotactin and localizing the dominant enhancers of the trio mutant phenotype. --Studied the effects of the cancer gene Bcr-Abl (associated with Chronic Myelogenous Leukemia) on nervous system development in Drosophila melanogaster. This project resulted in 1 middle author publication. Investigating Neurotactin and localizing the dominant enhancers of the trio mutant phenotype. --Studied the effects of the cancer gene Bcr-Abl (associated with Chronic Myelogenous Leukemia) on nervous system development in Drosophila melanogaster. This project resulted in 1 middle author publication.