Experience

FutureNeuro

• Ireland
• Research
• 1 - 100 Employee

• Postdoctoral Researcher

  • Sep 2022 - Present

• Researcher PhD Student

  • May 2018 - Aug 2022

  During my PhD I worked on a collaborative project with the pharmaceutical industry to explore the potential of a miRNA-based therapy for epilepsy.



Universidade Federal de Santa Maria

• Brazil
• Higher Education
• 700 & Above Employee

• Masters Research

  • Aug 2013 - Jan 2016

  Project title: Guanosine reduces neurotoxicity and motor deficit induced by traumatic brain injury in rats.This project involved the investigation of Guanosine effects on several neurotoxic events following traumatic brain injury in rats. A combination of molecular and biochemical approaches were employed, including dot blot, immunostaining, cytokine Immunoassay kits, [3H] glutamate uptake (slice) and release (crude synaptosomes), oxidative stress, enzymatic and mitochondria assays by colorimetric methods. Stereotaxic surgeries (placement of cortical electrodes to EEG recordings and cannula implantation to induce traumatic brain injury) and behavioral evaluation (memory and motor/locomotion tests) were also performed.

• Training for In vivo Research Scientist - Neuroscience/Biochemistry (Undergraduate level)

  • Feb 2010 - Jul 2013

  Project title: Ergogenic compounds and physical exercise as a therapeutic strategy in acute epileptic seizures and post-traumatic seizures in rats/mice.This project involved the characterization of caffeine and creatine supplementation effects in pentylenetetrazol-induced acute seizures. Moreover, the role of creatine supplementation and physical exercise on susceptibility to epileptic seizures after traumatic brain injury were investigated. A combination of skills were employed on this project including: stereotaxic surgeries (EEG electrodes; cannula implant to delivery drugs (i.c.v); craniectomy to implant the traumatic brain injury cannula in the FPI model. Drug delivery (oral gavage, intraperitoneal and Intracerebroventricular injections). Induction of exercise (swimming and treadmill exercise). Behavior assessment based on Racine scale (Seizure severity). Biochemical analyses (enzyme activity assays and oxidative stress by colorimetric methods).