Experience

Meletios Therapeutics

• France
• Biotechnology Research
• 1 - 100 Employee

• Discovery Project Manager

  • Sep 2021 - Present

  Ville de Paris, Île-de-France, France



Regulaxis SAS

• France
• Biotechnology Research
• 1 - 100 Employee

• R&D Project manager

  • Jul 2017 - Aug 2021

  Romainville Missions : - Preclinical phase management for the lead candidate molecule (REG-O3) in the frame of osteoarthritis therapeutics - Identification of the competencies needed for the clinical phase and international network of experts implementation - Clinical trial phase design in collaboration with the Chief Scientific Officer (CSO) - Elucidation of the mechanism of action of REG-O3 internally Management skills : - Search for CROs, academic collaborators and partnership with… Show more Missions : - Preclinical phase management for the lead candidate molecule (REG-O3) in the frame of osteoarthritis therapeutics - Identification of the competencies needed for the clinical phase and international network of experts implementation - Clinical trial phase design in collaboration with the Chief Scientific Officer (CSO) - Elucidation of the mechanism of action of REG-O3 internally Management skills : - Search for CROs, academic collaborators and partnership with other SMEs - Contracts set up and management - Coordination of the international network for the writing of regulatory documents (study reports, IMPD) - Team projects management (Internal technical team, CROs, academic teams) - Scientific project management (timelines, budget, risks) - Quality control of the studies (GLP, GMP) - Implementation of the quality system in the company Communication skills : - Projects reporting to the CSO, partners and collaborators - Writing of a Scientific Technical Advise to the Belgian (FAMHP) and European (EMA) Health authorities - Presentation and discussion of data at internal and international meetings (2 oral communications during plenary sessions) - Scientific documents redaction (1 published scientific article, 40 internal study reports, 3 annual reports, 20 Standard Operating Procedures (SOPs), 9 abstracts and 5 posters) - Writing of a scientific project for European funds (Eureka-Eurostars) Scientific skills : - Study plans definition and design - Design and development of GLP experimental procedures - Analyses and interpretation of results - Team working and troubleshooting abilities - Literature and technologic survey - Review of scientific projects involving animals (member of the ethics committee on animal experimentation n°80) One publication in PLoS One journal. 2020 Apr 14;15(4):e0231240. Oral Communications at the: - ICRS meeting 5th-8th october 2019 (Vancouver, Canada). - OARSI meeting 26th-29th april 2018 (Liverpool, UK). Show less



Institut Cochin

• France
• Research
• 1 - 100 Employee

• Research Associate

  • Mar 2012 - Mar 2016

  Ville de Paris, Île-de-France, France Mission : - Elucidation of the genetics, molecular and cellular mechanisms of the neurological features in the frame of OCRL mutations (Lowe syndrome vs Dent disease-2) Management skills : - Technical team supervision (2 technicians, 3 students) - Scientific project management (timelines, budget, risks) - National and International collaboration (France, Germany) - In charge of consumable (inventory management) - In charge of a wild-field microscope Communication… Show more Mission : - Elucidation of the genetics, molecular and cellular mechanisms of the neurological features in the frame of OCRL mutations (Lowe syndrome vs Dent disease-2) Management skills : - Technical team supervision (2 technicians, 3 students) - Scientific project management (timelines, budget, risks) - National and International collaboration (France, Germany) - In charge of consumable (inventory management) - In charge of a wild-field microscope Communication skills : - Project reporting to the supervisor - Presentation and discussion of data internally and externally (6 poster presentations at both national/international meetings) - Data presentation to financial support organizations (3 oral communications) - Scientific documents redaction (4 published scientific articles, 9 abstracts and 6 posters) - Writing of 3 scientific projects for funds (3 grants obtained via Orange Foundation, Jérôme Lejeune Foundation, French Lowe Syndrome Association) Scientific skills : - Design and development of GLP experimental procedures - Analyses and interpretation of results - Team working and troubleshooting abilities - Literature survey 4 Publications : - 2 Molecular Psychiatry-2018 and 2016 - 1 Human Mutation-2017 - 1 Human Molecular Genetics-2015 Oral communications at the Assemblée Générale de l’Association du Syndrome de Lowe in Paris (France) : - 19th march 2016 - 3rd may 2014 - 6th april 2013 Poster communications at the : - 2nd International GENCODYS Conference Integrative Networks in Intellectual Disabilities (Chania, Crete, Greece. 27th-29th April 2015) - EMBO Conference-Autism and related disorders: From bench to bed (La Ciotat, France. 5th-8th September 2014) - Congress of Young Researchers-René Descartes (Paris, France. October 2013) - 4th European Synapse Meeting (Bordeaux, France. 28th-30th August 2013) - Gencodys 1st international conference, Integrative networks in intellectual disabilities (Paphos, Chypre. 15-17th april 2013) Show less



Hôpital Necker Enfants Malades

• France
• Civic and Social Organizations

• Research Associate

  • Jan 2010 - Feb 2012

  Ville de Paris, Île-de-France, France Mission : - Study the normal and pathological role of nephrocystins 1 and 4 genes that are associated with nephronophthisis Management skills : - Scientific project management (timelines, budget, risks) - National and International collaboration (France, Denmark) Communication skills : - Project reporting to the supervisor - Presentation and discussion of data internally and externally (4 poster presentations at international meetings) - Scientific documents… Show more Mission : - Study the normal and pathological role of nephrocystins 1 and 4 genes that are associated with nephronophthisis Management skills : - Scientific project management (timelines, budget, risks) - National and International collaboration (France, Denmark) Communication skills : - Project reporting to the supervisor - Presentation and discussion of data internally and externally (4 poster presentations at international meetings) - Scientific documents redaction (2 published scientific articles, 4 abstracts and 4 posters) - Participation in scientific articles reviewing Scientific skills : - Design and development of GLP experimental procedures - Analyses and interpretation of results - Team working and troubleshooting abilities - Literature survey Publications : - 1 in PLoS One journal. 2013 Apr 8, 8(4). - 1 in New England Jpurnal of Medicine. 2011 Dec 22; 365 (25):2377-88. Oral communication at the : - ASN, kidney week 2011 (Philadelphia, USA. 10th-13th november 2011). Poster communications at the : - Cilia 2012, 1st international scientific conference (London, UK. 17th-18th may 2012). - 6èmes journées «Cils, flagelles, centrosomes» (Lyon, France. 15th-16th november 2011). - 5èmes journées «Cils, flagelles, centrosomes» (Dourdan, France. 20th-21th october 2010). Show less

• Research Associate

  • Nov 2008 - May 2009

  Ville de Paris, Île-de-France, France Mission : - Elucidate the molecular and cellular mechanisms involved in the renal features of the Lowe syndrome Management skills : - Scientific project management (timelines) - National collaboration - Students supervision - In charge of cell culture reagents (testing, inventory management) Communication skills : - Project reporting to the supervisor - Presentation and discussion of data internally and externally (1 poster presentation during a national… Show more Mission : - Elucidate the molecular and cellular mechanisms involved in the renal features of the Lowe syndrome Management skills : - Scientific project management (timelines) - National collaboration - Students supervision - In charge of cell culture reagents (testing, inventory management) Communication skills : - Project reporting to the supervisor - Presentation and discussion of data internally and externally (1 poster presentation during a national meeting) Scientific skills : - Design and development of GLP experimental procedures - Analyses and interpretation of results - Team working and troubleshooting abilities - Literature survey Poster communication at the : - 12th annual meeting of the «club Exocytose-Endocytose» (Presqu'île de Giens, France. 4th-6th june 2009) Show less

• PhD student

  • 2004 - 2008

  Ville de Paris, Île-de-France, France Mission : - Elucidate the molecular and cellular mechanisms involved in the renal features of the Lowe syndrome Management skills : - Scientific project management (timelines) - National collaboration - Students supervision - In charge of cell culture reagents (testing, inventory management) Communication skills : - Project reporting to the supervisor - Presentation and discussion of data internally and externally (7 poster presentations at national and… Show more Mission : - Elucidate the molecular and cellular mechanisms involved in the renal features of the Lowe syndrome Management skills : - Scientific project management (timelines) - National collaboration - Students supervision - In charge of cell culture reagents (testing, inventory management) Communication skills : - Project reporting to the supervisor - Presentation and discussion of data internally and externally (7 poster presentations at national and international meetings) - Scientific documents redaction (1 published scientific article, 8 abstracts and 8 posters) - Writing of 4 scientific projects for funds (4 grants obtained via Association pour la Recherche sur le Cancer, Fondation pour la Recherche Médicale, Conseil Régionale de la Martinique, French Lowe Syndrome Association) Scientific skills : - Design and development of GLP experimental procedures - Analyses and interpretation of results - Team working and troubleshooting abilities - Literature survey One Publication in Cancer Research Journal. 1 November 2012, 72 (21) :5505-15. Poster communications at the : - American Association for the Study of Liver Diseases: Liver Meeting (Boston, USA. 29th oct- 2nd november 2010) - Mental Retardation: from genes to synapses, functions and dysfunctions Meeting (Roscoff, France. 7th-11th November 2010) - 11éme forum de l'école doctorale Gc2iD (Rueil-Malmaison, France. 20th-21th march 2008) - 10éme forum de l'école doctorale Gc2iD (Rueil-Malmaison, France. 30th-31th march 2007) - Cell migration in development and disease Meeting (Paris, France. 20th-21th November 2006) - Colloque des «petites protéines G» (Toulouse, France. May 2005). - Colloque «GIS maladies rares» (30th-31th may 2005). Show less



Hopital Saint-Antoine

• France
• Civic and Social Organizations
• 1 - 100 Employee

• Master Student

  • Sep 2002 - Jul 2003

  paris INSERM U482 Signal transduction and cellular functions in diabetes and digestives cancers team supervised by Dr Christian Gespach. Research topic: Impact of PRA/PRB ratio modulation on apoptosis in breast cancer cell lines.