Rebecca J Erickson

Analytical Project Lead - Histology at MLM Medical Labs
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Contact Information
us****@****om
(386) 825-5501
Location
St Paul, Minnesota, United States, US
Languages
  • Spanish -

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Experience

    • Germany
    • Biotechnology Research
    • 1 - 100 Employee
    • Analytical Project Lead - Histology
      • Nov 2020 - Present

      • Histology division lead scientist, Study Director, and Project Manager for CRO providing histology and image analysis services to the pharmaceutical industry in the oncology, immunology, and inflammation fields. • Oversight and pricing of many high-value, complex clinical-phase, translational, and preclinical Sponsor projects from proposal through execution. • Primary liaison between clients, internal MLM teams (scientists and business development), and Pathologists. • Guidance… Show more • Histology division lead scientist, Study Director, and Project Manager for CRO providing histology and image analysis services to the pharmaceutical industry in the oncology, immunology, and inflammation fields. • Oversight and pricing of many high-value, complex clinical-phase, translational, and preclinical Sponsor projects from proposal through execution. • Primary liaison between clients, internal MLM teams (scientists and business development), and Pathologists. • Guidance of assay development, validation, and verification for immunohistochemistry (IHC), immunofluorescence (IF), in situ hybridization (ISH), multiplex immunostaining, and other histology assays. • Comprehensive understanding of the digital pathology market and applications. • Digital pathology systems management including whole slide imaging, quantitative image analysis (Visiopharm), and cloud-based image database management (Pathcore). • Handling of study data via CLIA-compliant sample/result tracking system and coordination with client data transfer needs. • Image analysis algorithm development and use (Visiopharm). Includes use of machine learning and AI tools. Show less • Histology division lead scientist, Study Director, and Project Manager for CRO providing histology and image analysis services to the pharmaceutical industry in the oncology, immunology, and inflammation fields. • Oversight and pricing of many high-value, complex clinical-phase, translational, and preclinical Sponsor projects from proposal through execution. • Primary liaison between clients, internal MLM teams (scientists and business development), and Pathologists. • Guidance… Show more • Histology division lead scientist, Study Director, and Project Manager for CRO providing histology and image analysis services to the pharmaceutical industry in the oncology, immunology, and inflammation fields. • Oversight and pricing of many high-value, complex clinical-phase, translational, and preclinical Sponsor projects from proposal through execution. • Primary liaison between clients, internal MLM teams (scientists and business development), and Pathologists. • Guidance of assay development, validation, and verification for immunohistochemistry (IHC), immunofluorescence (IF), in situ hybridization (ISH), multiplex immunostaining, and other histology assays. • Comprehensive understanding of the digital pathology market and applications. • Digital pathology systems management including whole slide imaging, quantitative image analysis (Visiopharm), and cloud-based image database management (Pathcore). • Handling of study data via CLIA-compliant sample/result tracking system and coordination with client data transfer needs. • Image analysis algorithm development and use (Visiopharm). Includes use of machine learning and AI tools. Show less

    • Senior Scientist/ Project Manager
      • Nov 2019 - Nov 2020

      Oversight of preclinical and clinical histology projects including assay development and use. Digital pathology systems management and Pathologist coordination. Oversight of preclinical and clinical histology projects including assay development and use. Digital pathology systems management and Pathologist coordination.

    • United States
    • Higher Education
    • 700 & Above Employee
    • Postdoctoral Associate
      • Mar 2019 - Nov 2019

      Work included: • Project leadership • Experimental design, execution, and analysis • Assay and protocol development • Extensive use of confocal microscopy and other analytical equipment and technologies • Communication of results through presentations and publication Continuation of work in the lab or Gary Dunny, Ph.D. studying bacterial communication, gene transfer, and host colonization by Enterococcus faecalis. • Explored adaptation of bacteria and gene labeling… Show more Work included: • Project leadership • Experimental design, execution, and analysis • Assay and protocol development • Extensive use of confocal microscopy and other analytical equipment and technologies • Communication of results through presentations and publication Continuation of work in the lab or Gary Dunny, Ph.D. studying bacterial communication, gene transfer, and host colonization by Enterococcus faecalis. • Explored adaptation of bacteria and gene labeling methods to new in vivo and multi-species applications.

    • MinnCResT Predoctoral Fellow
      • Dec 2017 - Feb 2019

      My doctoral studies and work on single cell analysis of bacterial communication and gene transfer by Enterococcus faecalis were partially funded by a fellowship through the Minnesota Craniofacial Research Training (MinnCResT) Program. This program facilitated career development and exposure to problems in craniofacial research. https://www.dentistry.umn.edu/research/minnesota-craniofacial-research-training-minncrest-program

    • Doctoral Candidate
      • Jul 2015 - Feb 2019

      • Thesis work in the lab of Gary Dunny, Ph.D. focused on optimization, validation, and use of a new method for single cell gene expression characterization in Enterococcus faecalis and use of MATLAB for high-throughput fluorescence image analysis. Published use of this method advanced understanding of single cell variation of regulation involved in bacterial signaling and gene transfer. • Collaborated with lab of Wei-Shou Hu, Ph.D. in Chemical Engineering to pursue parallel systems biology… Show more • Thesis work in the lab of Gary Dunny, Ph.D. focused on optimization, validation, and use of a new method for single cell gene expression characterization in Enterococcus faecalis and use of MATLAB for high-throughput fluorescence image analysis. Published use of this method advanced understanding of single cell variation of regulation involved in bacterial signaling and gene transfer. • Collaborated with lab of Wei-Shou Hu, Ph.D. in Chemical Engineering to pursue parallel systems biology approaches (including mathematical modeling, fluorescent reporters, and RNAseq). • Managed project to elucidate mechanisms of E. faecalis biofilm development and specifically how extracellular DNA is released into the biofilm matrix. Supervised an undergraduate researcher on development of an assay for detection of DNA within biofilms. • Used a novel triphosphate ligase to map transcription start sites validating new ligase utility. Skills developed: microbiology, molecular biology, systems biology, and biofilm methods, experiment and SOP design, fluorescence and confocal microscopy, MATLAB image analysis, next generation DNA/ RNA sequencing and analysis, bacterial mating, western blots, flow cytometry, mouse model of bacterial colonization. Publications on NCBI: https://www.ncbi.nlm.nih.gov/myncbi/browse/collection/57648568/?sort=date&direction=ascending MICaB program: http://micab.umn.edu/ Software Experience: • Productivity software: Microsoft Office suite, GoogleDrive • Programming languages and data, sequencing, transcriptomics, metagenomics, and image analysis tools: MATLAB, R, Cufflinks tools, Spotfire, Galaxy, LaserGene, Ape, Rockhopper, QIIME, SourceTracker, PICRUSt, FIJI, ImageJ, Huygens Pro, GraphPad, FlowJo, Command Line

    • Economic Development Fellows Consulting Program Intern
      • May 2017 - Sep 2017

      • Worked with a cross-functional team of interns to survey the current state of pipeline coating holiday defect detection technologies for Lake Superior Consulting. https://research.umn.edu/industry-partnership/fellows-consulting-program-0

    • NIGMS Biotechnology Trainee
      • Jul 2014 - Jul 2016

      My doctoral studies and work on single cell analysis of bacterial communication and gene transfer by Enterococcus faecalis were partially funded by the UMN Biotechnology Training Program. This program facilitated career development and cross-disciplinary interactions. http://www.bti.umn.edu/BiotechTraining/index.php

    • Graduate Teaching Assistant
      • Sep 2014 - Jun 2016

      Taught a laboratory section of MICB3301- Introductory Microbiology in Fall of 2014 and Spring of 2016. Lab of 30 students met twice a week for 2 hours. Prepared and gave lectures, co-wrote quizzes, and graded laboratory notebooks, lab reports, quizzes, and assignments.

    • Graduate Assistant
      • Aug 2013 - Jul 2015

      Completed graduate coursework, lab rotations, and began thesis work in the lab of Gary Dunny, Ph.D. on single cell analysis of bacterial communication and gene transfer by Enterococcus faecalis.

    • United States
    • Biotechnology Research
    • 700 & Above Employee
    • Graduate Intern
      • Sep 2016 - Nov 2016

      • Provided proof of concept for adaptation of a new technology to several new applications. • Presented new applications to CTO and various functional groups at Bio-Techne. • Interacted with acquired company leadership and tested acquired technology. • Provided proof of concept for adaptation of a new technology to several new applications. • Presented new applications to CTO and various functional groups at Bio-Techne. • Interacted with acquired company leadership and tested acquired technology.

    • Japan
    • Higher Education
    • 100 - 200 Employee
    • Visiting Graduate Researcher
      • Oct 2015 - Nov 2015

      • Became familiar with high-throughput phenotyping of Escherichia coli knock-out mutant libraries enabled by robots and computational image analysis while visiting the lab of Hirotada Mori, Ph.D. at the Nara Institute of Science and Technology (NAIST). NAIST: http://www.naist.jp/en/ Mori lab: https://bsw3.naist.jp/eng/courses/courses302.html • Became familiar with high-throughput phenotyping of Escherichia coli knock-out mutant libraries enabled by robots and computational image analysis while visiting the lab of Hirotada Mori, Ph.D. at the Nara Institute of Science and Technology (NAIST). NAIST: http://www.naist.jp/en/ Mori lab: https://bsw3.naist.jp/eng/courses/courses302.html

    • United States
    • Biotechnology Research
    • 1 - 100 Employee
    • Research Intern
      • Jul 2012 - Jul 2013

      Conducted research as an Undergraduate Lab Assistant and then as a Research Intern in the lab of Trey Sato, Ph.D. Work resulted in 4 peer-reviewed publications. • Successfully engineered, evolved, and characterized wild Saccharomyces cerevisiae yeast for the conversion of renewable cellulosic plants to biofuels through improved xylose utilization. Skills developed: genome engineering, PCR, electroporation and chemical transformation, operation of controlled fermentation bioreactors… Show more Conducted research as an Undergraduate Lab Assistant and then as a Research Intern in the lab of Trey Sato, Ph.D. Work resulted in 4 peer-reviewed publications. • Successfully engineered, evolved, and characterized wild Saccharomyces cerevisiae yeast for the conversion of renewable cellulosic plants to biofuels through improved xylose utilization. Skills developed: genome engineering, PCR, electroporation and chemical transformation, operation of controlled fermentation bioreactors, yeast mating, sporulation, tetrad dissection.

    • Undergraduate Lab Assistant
      • Jun 2010 - Jun 2012

    • Lifeguard/ Swim Instructor
      • Jun 2007 - Aug 2009

Education

  • University of Minnesota-Twin Cities
    Doctor of Philosophy (PhD), Microbiology, Immunology, and Cancer Biology
    2013 - 2019
  • University of Wisconsin-Madison
    BS, Biology, Microbiology, History of Science
    2008 - 2012

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