Experience

Ludger Limited

• United Kingdom
• Biotechnology Research
• 1 - 100 Employee

• Head of Production

  • Oct 2022 - Present

  Oxfordshire, England, United Kingdom • Leading the Production team to ensure successful delivery of all glycan analysis products to support sales • Leading finished good shipment to fulfil customer deliveries • Work with staff in Ludger to ensure minimum stock levels are maintained, provide training where required • Continual development of production staff • An integral part of a cross functional team to ensure the efficient running of the business • Maintaining and driving compliance improvements • Liaising… Show more • Leading the Production team to ensure successful delivery of all glycan analysis products to support sales • Leading finished good shipment to fulfil customer deliveries • Work with staff in Ludger to ensure minimum stock levels are maintained, provide training where required • Continual development of production staff • An integral part of a cross functional team to ensure the efficient running of the business • Maintaining and driving compliance improvements • Liaising with Business Development to provide input into product availability for sales order fulfilment, marketing strategies and supporting documents • Develop plans to ensure long term client support are initiated and maintained • Responsible for budget setting, business planning and meeting sales targets. • Communicating production activities to the wider organisation • Providing technical support for Ludger clients • Collaborating with all internal teams to ensure Ludger goals and targets are achieved • Supporting the Glycoprofiling team with ensuring products are available in a timely manner

• Lead Scientist

  • Oct 2019 - Oct 2022

  Culham Science Centre, Abingdon, Oxford

• Senior Scientist

  • Jul 2005 - Oct 2022

  Culham Science Centre, Abingdon, Oxford Key responsibilities • Project leader: Development and automation of Ludger sample preparation and analytical methods, including modifying and optimising current methods, for automation and higher throughput analysis of protein glycosylation. • Integration of multiple glycoanalytical techniques, UHPLC, LC-MS and MALDI, to provide a platform for higher throughput, orthogonal analysis of glycoproteins. • Technically assessing and applying developed, automated methods for comparison of… Show more Key responsibilities • Project leader: Development and automation of Ludger sample preparation and analytical methods, including modifying and optimising current methods, for automation and higher throughput analysis of protein glycosylation. • Integration of multiple glycoanalytical techniques, UHPLC, LC-MS and MALDI, to provide a platform for higher throughput, orthogonal analysis of glycoproteins. • Technically assessing and applying developed, automated methods for comparison of biopharmaceutical glycoproteins and glycomics samples for comparability studies and biomarker discovery. • Project leader: Ludger’s GX-mAb glycosylation service (HTP glycoanalysis of monoclonal antibody therapeutics) involving the development, implementation and running of the service: study proposals and plans, sample reception, sample preparation, sample analysis, data analysis, report writing, liaising with clients • Product champion: Product and method development within R&D to take new products from conception through to beta build and on to sales build and marketing using Ludger’s Development product pipeline. One of my responsibilities was as the Deputy for QC sign off of products. • Validation of Ludger glycoanalytical methods and technology, producing validation reports and documents in accordance with ISO9001:2008 framework and ICH Q2(R1) guidelines • Responsible for Glycoanalytical work for clients through glycoprofiling, Ludger’s CRO department, on various biopharmaceutical samples including mAbs, FSH, EPO and Biosimilars: sample reception, sample preparation, sample analysis, data analysis, report writing, liaising with clients.



Evotec

• Germany
• Pharmaceutical Manufacturing
• 700 & Above Employee

• Senior Scientist

  • Oct 2004 - Jun 2005

  Key responsibilities Process Research and Development: Development of alternative routes to synthesize final compounds, route scouting and small scale chemistry. Custom Prep: Synthesis of API to cGMP up to 20L scale in the laboratory. Key experience Working as a member of different teams, working to tight deadlines. GMP trained and experienced.



University of Central Florida

• United States
• Higher Education
• 700 & Above Employee

• Postdoctoral Fellow: Organic/Bioorganic Chemistry

  • Mar 2002 - Feb 2004

  Key Research Synthesis of acinetoferrin homologues and petrobactin and homologues (bacterial iron chelators) as probes for iron transport in bacteria, synthesis of beta-amino peptides, synthesis of lipophilic-polyamine DNA vectors, synthesis of aryl-polyamine conjugates to probe the polyamine transport system. Position obtained by personal contact with Otto Phanstiel at the Gordon Conference on Polyamines in June 2001. Key experience Writing a number of peer-reviewed publications… Show more Key Research Synthesis of acinetoferrin homologues and petrobactin and homologues (bacterial iron chelators) as probes for iron transport in bacteria, synthesis of beta-amino peptides, synthesis of lipophilic-polyamine DNA vectors, synthesis of aryl-polyamine conjugates to probe the polyamine transport system. Position obtained by personal contact with Otto Phanstiel at the Gordon Conference on Polyamines in June 2001. Key experience Writing a number of peer-reviewed publications on different synthetic pathways. Undergraduate supervision Show less