Experience

SyntheticGestalt

• United Kingdom
• Biotechnology
• 1 - 100 Employee

• Research Engineer

  • Sep 2020 - Present



Silver Egg Technology

• Japan
• Technology, Information and Internet
• 1 - 100 Employee

• Research And Development Scientist

  • Jul 2018 - Aug 2020

  Researching and developing prototype recommender systems, primarily for e-commerce websites. Researching and developing prototype recommender systems, primarily for e-commerce websites.



Doctoral Training Centre, University of Oxford

• Education Administration Programs
• 1 - 100 Employee

• DPhil

  • Oct 2013 - Apr 2018

  DPhil (PhD) in the Systems Approaches to Biomedical Science Industrial Doctorate Centre, based in the Computational Biology group in the Department of Computer Science, University of Oxford.DPhil thesis: "Uncertainty characterisation in action potential modelling for cardiac drug safety".We use Bayesian statistical models to characterise uncertainty in mathematical models of heart cell bioelectrical behaviour and in drug screening data. These uncertainties are propagated into heart cell model predictions of how a particular drug will affect the cell's bioelectrical behaviour. We obtain a range of possible responses with associated probabilities, allowing for better-informed decision making when assessing a drug's cardiac risk.Data visualisation and statistical algorithms are implemented in Python which interfaces with the Chaste C++ library.



Roche

• Switzerland
• Biotechnology Research
• 700 & Above Employee

• Visiting PhD Student

  • Jan 2017 - Feb 2017

  I spent two months in Liudmila Polonchuk's lab performing manual patch clamp experiments on stem cell-derived cardiomyocytes (SCCMs).I was recording action potentials (APs), both stimulated and spontaneous, in membrane voltage from SCCMs. APs were recorded in control solution and then in increasing concentrations of ion channel-blocking compounds.We fitted a range of mechanistic AP models to our recorded AP data within a larger statistical model to quantify some of the uncertainty associated with such computational modelling. Together with uncertainty quantification in ion channel screening data, we attempted to propagate uncertainty into larger-scale predictions of heart-compound interactions.



Mathematical Institute, University of Oxford

• Intercollegiate Class Tutor

  • 2015 - 2016

  Class tutor for 3rd year undergraduate classes: Applied Partial Differential Equations and Stochastic Modelling of Biological Processes.

• Intercollegiate Class Teaching Assistant

  • 2014 - 2015

  Teaching assistant for 4th year undergraduate classes: Perturbation Methods and Mathematical Physiology.



Hertford College Middle Common Room

• Treasurer

  • Sep 2013 - Jul 2015

  The Middle Common Room (MCR) is the college's graduate student community. I worked on the executive committee for two years primarily managing the annual budget of approximately £30,000. The Middle Common Room (MCR) is the college's graduate student community. I worked on the executive committee for two years primarily managing the annual budget of approximately £30,000.