Renata Caikauskaite
Senior DNA Engineer at SynGenSys Limited- Claim this Profile
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Bio
Experience
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SynGenSys Limited
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United Kingdom
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Biotechnology Research
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1 - 100 Employee
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Senior DNA Engineer
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Feb 2022 - Present
Sheffield, England, United Kingdom At this job position, I am responsible for both laboratory-based and in silico computer-based research underpinning the design and development of novel nucleotide sequences intended to engineer recombinant gene expression in mammalian cells. Duties and responsibilities: (i) Maintaining and recording collections of DNA sequences, plasmid constructs and host mammalian cell lines, including detailed cell culture histories (ii) Support translation of technology to a cGMP environment… Show more At this job position, I am responsible for both laboratory-based and in silico computer-based research underpinning the design and development of novel nucleotide sequences intended to engineer recombinant gene expression in mammalian cells. Duties and responsibilities: (i) Maintaining and recording collections of DNA sequences, plasmid constructs and host mammalian cell lines, including detailed cell culture histories (ii) Support translation of technology to a cGMP environment (iii) Protecting confidential company intellectual property by maintenance of detailed laboratory and informatic records (iv) Maintaining technical competency and compliance with workplace health and safety requirements and procedures (v) Participation in marketing, administration and commercial development activity, including attendance at company client premises, conferences and related meetings (vi) Communication with customers (vii) Preparation and delivery of reports, presentations and technical evaluations (viii) Support of business and company strategic development - undertaking any relevant background research - with a responsibility for the preparation of documents and technical reports in support of patent applications and scientific publications (ix) Analysis and control of project planned resources, time and budget Show less
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The University of Sheffield
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Higher Education
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700 & Above Employee
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Research Associate in Mammalian Gene Expression
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Jun 2019 - Jan 2022
Sheffield, United Kingdom During this project, I carried out research and development of synthetic genetic vector components for biotechnological applications. This project, funded by the Connecting Capability Fund – Northern Triangle Initiative (HEFCE), aimed to provide industry-relevant proof-of-concept data that would support the spin-out of a new company. I used in-house resources and relevant literature to design novel synthetic DNA constructs with context-specific, industry-required design criteria to improve… Show more During this project, I carried out research and development of synthetic genetic vector components for biotechnological applications. This project, funded by the Connecting Capability Fund – Northern Triangle Initiative (HEFCE), aimed to provide industry-relevant proof-of-concept data that would support the spin-out of a new company. I used in-house resources and relevant literature to design novel synthetic DNA constructs with context-specific, industry-required design criteria to improve recombinant protein production by Chinese Hamster Ovary cell lines. Show less
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Manchester University NHS Foundation Trust
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United Kingdom
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Hospitals and Health Care
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1 - 100 Employee
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Wellcome Trust Biomedical Vacation Scholarship
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Jul 2013 - Aug 2013
Manchester, United Kingdom Project title: Inflammatory Response of Human Alveolar Macrophages in Chronic Obstructive Pulmonary Disease: Co-interaction between Fcγ-receptors and TLRs.
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Medicines Evaluation Unit Ltd
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United Kingdom
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Research Services
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1 - 100 Employee
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Student Research Technician
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2012 - 2013
Manchester, United Kingdom Duties and Responsibilities: • Performance and documentation of physiological measurements on clinical trial volunteers • Assisting in the planning, administration and conduct of clinical trials • Performing laboratory techniques under the Health and Safety Guidelines • Assisting with general care and welfare of volunteers • Working under Standard Operating Procedure (SOP) Guidelines
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Manchester University NHS Foundation Trust
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United Kingdom
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Hospitals and Health Care
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1 - 100 Employee
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Student Research Technician
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2012 - 2013
Manchester, United Kingdom Laboratory-based Sandwich Placement Project (Grade achieved 85%): Inflammatory Response of Human Alveolar Macrophages in Chronic Obstructive Pulmonary Disease: Co-interaction between Fcγ-receptors and TLRs. Duties and Responsibilities: • Performing laboratory techniques under the Health and Safety Guidelines • Usage of aseptic techniques • Documentation of patient consents • Participating in seminars, laboratory meetings and presentations
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Education
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The University of Sheffield
Doctor of Philosophy - PhD, Cell/Cellular and Molecular Biology -
The University of Salford
BSc (Hons) Human Biology & Infectious Diseases, (1st Class) -
Public Kaunas ‘Vyturys’ Catholic Secondary School
Secondary Education Certificate, (9.42 out of 10)