Experience

TISSO Naturprodukte GmbH

• Germany
• Wellness and Fitness Services
• 1 - 100 Employee

• Head of Research & Development

  • Jul 2013 - Present

  • Development and optimization of nutritional supplements• Seminars/presentations: silent inflammation, mitochondrial medicine, microbiome, nutritional strategies for health

• Research and Development

  • Oct 2012 - Present

  www.tisso.de



n/a

• Berlin Area, Germany

• Grant Writing

  • Feb 2012 - May 2012

  Gene Therapy / in vivo Stem Cell Therapy for Type 1 Diabetes Gene Therapy / in vivo Stem Cell Therapy for Type 1 Diabetes



Cenix BioScience

• Biotechnology Research

• Research Scientist, In vivo RNAi Unit

  • Nov 2008 - Jul 2011

  • Development and patenting of an siRNA delivery technology • Coordination with external companies and consultant • Design of chemically modified siRNA to minimize immune response • Heading the internal testing • in vivo testing of a commercial siRNA delivery technology • Development and patenting of an siRNA delivery technology • Coordination with external companies and consultant • Design of chemically modified siRNA to minimize immune response • Heading the internal testing • in vivo testing of a commercial siRNA delivery technology



University of Alabama at Birmingham

• Higher Education
• 700 & Above Employee

• Postdoctoral Fellow

  • Jan 2005 - Sep 2008

  • Development of a melanoma vaccine that targets dendritic cells in vivo • Tested promoter activity in vivo using adenoviral vectors • Tested the tolerable limit for replication competent adenovirus in viral preparations • Published review on targeted viral vectors in Nature Reviews Genetics • Wrote grant applications and animal protocols • Development of a melanoma vaccine that targets dendritic cells in vivo • Tested promoter activity in vivo using adenoviral vectors • Tested the tolerable limit for replication competent adenovirus in viral preparations • Published review on targeted viral vectors in Nature Reviews Genetics • Wrote grant applications and animal protocols



Universitätsklinikum Hamburg Eppendorf

• Germany
• Hospitals and Health Care
• 700 & Above Employee

• PhD student / Postdoc

  • 2000 - 2004

  • Designed, constructed and tested adenoviral vectors in vitro and in vivo • Developed a complex tricistronic expression cassette for cancer immunotherapy • Led team (surgeon, radiologist, technical staff) in preclinical testing of adenoviral vectors • Results led to patent and the founding of Provecs Medical --- Cancer gene therapy: Using adenoviral vectors I developed an immunostimulatory approach to enable the immune system to eliminate the tumor. Two tumor nodules were implanted into separate liver lobes. Only one nodule was treated. Using MRI, the shrinkage of both tumors could be monitored. While none of the animals in the control group survived, long term survival in treated groups was greater than 90%. Show less



Max Delbrück Center

• Germany
• Research Services
• 500 - 600 Employee

• PhD student

  • Dec 1998 - Jan 2000

  Please see description under PhD student / Scientist (UKE) above. Initial work at the Max Delbrueck Center also included the development of a production system for gutless adenoviral vectors (a.k.a. minimal or helper-dependent adenoviral vectors). Eventually this part of my PhD work was discontinued. Please see description under PhD student / Scientist (UKE) above. Initial work at the Max Delbrueck Center also included the development of a production system for gutless adenoviral vectors (a.k.a. minimal or helper-dependent adenoviral vectors). Eventually this part of my PhD work was discontinued.



University of Tuebingen

• Research Services
• 300 - 400 Employee

• Research Associate

  • 1997 - Oct 1998

  • Ribozyme technology • Transcription factors • Ribozyme technology • Transcription factors



Bayer

• Chemical Manufacturing
• 700 & Above Employee

• Internship

  • Mar 1995 - Apr 1995

  Bayer AG, Wuppertal, Germany • Cloned fibrosis related marker from mRNA library, expressed and column-purified it The internship was followed up by a second stay in the same laboratory as a working student in 1995. Bayer AG, Wuppertal, Germany • Cloned fibrosis related marker from mRNA library, expressed and column-purified it The internship was followed up by a second stay in the same laboratory as a working student in 1995.



The Wistar Institute

• United States
• Research Services
• 200 - 300 Employee

• Internship

  • Sep 1994 - Dec 1994

  • Studied and tested ribozyme technology, learned basic molecular biology • Studied and tested ribozyme technology, learned basic molecular biology