Regent Laporte
Course Director, Translational Science at University of California, San Diego - School of Medicine- Claim this Profile
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Bio
Experience
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UC San Diego School of Medicine
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United States
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Higher Education
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200 - 300 Employee
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Course Director, Translational Science
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Aug 2015 - Present
Designed, developed, and direct specific courses in Translational Science for the Master of Advanced Studies (MAS) in Clinical Research Program that were shared with the Translational Science Certificate Program.CLRE-236 - Translational Research Fundamentals (foundational course) since 2016CLRE-238 - Applied Translational Research I (case-study course) since 2017CLRE-239 - Applied Translational Research II (experiential course) from 2020 to 2023
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Program Director, Translational Science Certificate
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Jan 2019 - Jun 2023
At the Altman Clinical and Translational Research Institute, designed, developed, and directed a 10-unit Translational Science Certificate Program targeting postdoctoral scholars and PhD-level biomedical industry professionals and comprising a faculty of about 20 subject matter experts from a wide breadth of disciplines who are all seasoned R&D leaders from the biomedical industry, including several at the C-suite level.
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Resuscitation Therapeutics
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Chicago, Illinois, United States
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Scientific Advisor
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Oct 2019 - Present
At a startup biomedical company with the mission of developing and commercializing new therapies and strategies for resuscitation from life-threatening medical emergencies in pre-hospital and hospital settings in civilian and military environments, provide scientific and R&D advice on existing programs and formulate proposals for new programs. At a startup biomedical company with the mission of developing and commercializing new therapies and strategies for resuscitation from life-threatening medical emergencies in pre-hospital and hospital settings in civilian and military environments, provide scientific and R&D advice on existing programs and formulate proposals for new programs.
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Laporte & Associates LLC - Biotech & Pharma R&D Consultants
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San Diego, California, United States
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Founder & Principal Consultant
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Jun 2015 - Present
Advise biotechnology and pharmaceutical industry clients as well as academic institution clients on (i) preclinical proof of mechanism, proof of principle, and proof of concept strategies to identify and validate new drug ideas/drug lead compounds, (ii) drug lead compounds optimization strategies, and (iii) mechanism of action studies. Write regulatory documents, grant proposals, and scientific papers. Provide scientific review (due diligence) for in-licensing opportunities and non-clinical study proposals for marketed and clinical candidate drugs. Directed in vivo non-clinical studies on behalf of a medium-size pharmaceutical company client to elucidate a novel mechanism of action of a candidate drug that was in Phase 2 clinical trials. Contributed for an academic institution client to the writing of a research grant proposal that got funded (US Defense Medical Research and Development Program (DMRDP); US$1,322,169); contributing to the studies as co-investigator. Conducted due diligence review of non-clinical investigator-initiated study proposals for marketed products and candidate drugs for a medium-size pharmaceutical company client. Advised as subject matter expert a medium-size pharmaceutical company client on an ex vivo non-clinical study using human tissues to support a candidate drug that was in Phase 1 clinical trial. Show less
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Peptide Logic
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United States
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Biotechnology Research
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1 - 100 Employee
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Consultant, Translational Pharmacology
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Oct 2017 - May 2023
At a startup biopharmaceutical company combining the advantages of synthetic peptides and recombinant antibodies to create new biologics for the treatment of pain and other pathological conditions in select therapeutic areas, (i) supervised, advised, and guided research staff, (ii) participated in R&D program review meetings, (iii) contributed to grant applications, patent applications, and scientific articles, and (iv) participated in business development meetings, discussions, and interactions with pharmaceutical companies and investors. Contributed to 8 research grant proposals (NIH Small Business Innovation Research (SBIR) Program); secured all grants for a total sum of US$5,330,595. Show less
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Ferring Pharmaceuticals
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Switzerland
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Pharmaceutical Manufacturing
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700 & Above Employee
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Director of Exploratory Pharmacology
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Jan 2009 - Jun 2015
Held primary responsibility over global research in emergency/critical care medicine and in hepatology. Reviewed and selected ideas for best-in-class and first-in-class peptide therapeutics concepts from academia and private sector competition for drug discovery projects. Set and executed drug discovery research priorities. Established and cultivated a business network of key opinion leaders and consultants to maintain access to the most up-to-date scientific and clinical knowledge in comparative medicine, physiology, and pharmacology. Conducted scientific review (due diligence) of in-licensing opportunities. Supported marketed products and clinical candidate drug development.Spearheaded drug discovery team with responsibility for designing the clinical candidate drug selepressin (FE 202158), a selective vasopressin type V1A receptor (V1AR) agonist for vasodilatory hypotension in septic shock now in Phase 2b clinical trial at Ferring Pharmaceuticals. Named co-inventor on several patents related to selepressin.For entirety of tenure at Ferring, led teams that conducted or contributed to multiple feasibility projects (i.e., preclinical experimental validation of new drug ideas) and drug discovery projects leading to 8 new molecular entities/clinical candidate drugs now in clinical development. Show less
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Director of Integrative Pharmacology
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Jan 2006 - Dec 2008
Supervised the creation of the Vivarium/Animal Care Facility and the Institutional Animal Care and Use Committee (IACUC); directed/chaired administration over the course of five years.
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Director of Urology (Research)
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Jan 2005 - Dec 2005
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Director of Urology and Gastroenterology (Research)
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Jan 2004 - Dec 2004
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Associate Director of In Vivo Pharmacology
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Jan 2003 - Dec 2003
Created and directed the Department of In Vivo Pharmacology for over twelve years under various missions (reflected by its changing name).
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Senior Scientist and Group Leader of Obstetrics/Gynecology and Urology (Research)
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Jan 2001 - Dec 2002
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Scientist and Group Leader of Obstetrics/Gynecology and Urology (Research)
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Sep 2000 - Dec 2000
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Harvard Medical School
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United States
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Higher Education
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700 & Above Employee
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Instructor in Obstetrics, Gynecology, and Reproductive Biology
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Jul 2000 - Aug 2000
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Research Fellow in Obstetrics, Gynecology, and Reproductive Biology
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Jan 1997 - Jun 2000
Established a laboratory dedicated to the study of human and animal uterine smooth muscle.Developed various experimental methods adapted for the study of human and animal uterine smooth muscle: protein extraction and purification, immunoassays (including Western blot and ELISA), monitoring of smooth muscle contractile properties in tissue bath.Trained and directed support personnel: visiting gynecologists, obstetricians and anesthesiologists, research assistants.
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Tutor in Human Systems - Renal, Endocrine, and Reproductive Pathophysiology
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Sep 1998 - Dec 1999
Led and taught case study groups of 2nd year medical students.
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Research Fellow in Cardiology
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Jan 1995 - Dec 1996
Developed a cellular permeabilization method to introduce peptides into living vascular smooth muscle tissue and freshly isolated cells to assess the effects of these peptides on contractile function.
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Boston Biomedical Research Institute
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United States
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Research Services
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1 - 100 Employee
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Research Fellow in Cardiology
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Jan 1995 - Dec 1996
Developed a cellular permeabilization method to introduce peptides into living vascular smooth muscle tissue and freshly isolated cells to assess the effects of these peptides on contractile function. Developed a cellular permeabilization method to introduce peptides into living vascular smooth muscle tissue and freshly isolated cells to assess the effects of these peptides on contractile function.
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Université de Montréal
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Higher Education
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700 & Above Employee
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Instructor - Introduction to Biostatistics
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Sep 1986 - Aug 1990
Lectured classes of Bachelor of Nursing students.
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Instructor - Elements of Biometry
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Sep 1986 - Aug 1990
Lectured classes of 2nd year veterinary medical students.
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Education
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University of Vermont College of Medicine
Doctor of Philosophy (PhD), Pharmacology -
Université de Montréal
Master of Science (MS), Veterinary Anatomy and Physiology -
Université de Montréal
Doctor of Veterinary Medicine (DVM), Veterinary Medicine