Bioinformatics Scientist I

• Jul 2022 - Present

Research and Development • Investigate and compare available algorithms, methods and data sources. • Make recommendations for pipeline component improvements or new pipelines. Data Maintenance • Investigate available annotation and reference data sources. • Validate and deploy/update selected data sources. Validation • Develop appropriate procedures for testing and validation of new or updated pipelines or pipeline components. • Document and maintain data used for testing and validation. Show less

Bioinformatics Scientist

• May 2021 - Jun 2022

• Develop and maintain bioinformatics database update automation procedure; • Improve genetic risk prediction pipeline and present actionable genetic reports to physicians and patients; • Develop and build mathematical models and bioinformatics pipeline to support DNA sequencing analysis. • Develop and maintain bioinformatics database update automation procedure; • Improve genetic risk prediction pipeline and present actionable genetic reports to physicians and patients; • Develop and build mathematical models and bioinformatics pipeline to support DNA sequencing analysis.

Student Researcher

• Jul 2019 - May 2021

Used simulated annealing strategy to predict the bacterial growth rate based on a database including E. coli transcriptome (RNA-seq) data, culturing conditions, and growth rates collected from 594 experiments

Graduate Student

• Sep 2018 - Dec 2019

PHD Candidate

• Sep 2011 - May 2018

• Studied molecular mechanism of vitamin D-enhanced expression of cathelicidin, a human antimicrobial peptide in lung epithelial cells; • Delineated protection by vitamin D in mouse inflammatory bowel disease model and reported its correlation with enhanced tissue repair in colon epithelial cells; • Trained graduate students on experimental skills and ability to work independently. • Studied molecular mechanism of vitamin D-enhanced expression of cathelicidin, a human antimicrobial peptide in lung epithelial cells; • Delineated protection by vitamin D in mouse inflammatory bowel disease model and reported its correlation with enhanced tissue repair in colon epithelial cells; • Trained graduate students on experimental skills and ability to work independently.

Graduate Student

• Jul 2010 - May 2011

Built mathematical models to describe transdermal drug delivery processes: - Predicted optimal design of chemically-driven drug delivery system; - Coordinated with a collaborator on experimental data for model validation; - Pinpointed values of key parameters with non-linear regression method for drug delivery processes. Built mathematical models to describe transdermal drug delivery processes: - Predicted optimal design of chemically-driven drug delivery system; - Coordinated with a collaborator on experimental data for model validation; - Pinpointed values of key parameters with non-linear regression method for drug delivery processes.