Experience

Sandor Speciality Diagnostics Pvt. Ltd.

• India
• Biotechnology Research
• 1 - 100 Employee

• Head Of Department, Proteomics Services

  • Mar 2022 - Present



Neuland Laboratories Limited

• India
• Pharmaceutical Manufacturing
• 700 & Above Employee

• Sr Scientist (Manager-ARD)

  • May 2021 - Mar 2022

  Handling team of peptide method development, characterization, method transfer to plant. understand clients requirement and make the project plan. Handling team of peptide method development, characterization, method transfer to plant. understand clients requirement and make the project plan.



Biocon

• India
• Biotechnology Research
• 700 & Above Employee

• Associate Scientific Manager

  • Jan 2019 - May 2021

  Synthetic peptides characterization team impurity profiling, disulfide linkage study, DMF, MHRA, EMA report preparation, method development on CD, cIEF, LCMS Synthetic peptides characterization team impurity profiling, disulfide linkage study, DMF, MHRA, EMA report preparation, method development on CD, cIEF, LCMS



Aurobindo Pharma

• Hyderabad Area, India

• SCIENTIST -ARD-LCMS

  • Aug 2016 - Dec 2018

  • Responsible for leading small team of peptide characterization (Intact molecular weight, peptide sequencing, Intra and Inter disulfide bonds study) by LCMS (Q-Tof,TQS,) • method development for impurities profiling of API drug by LCMS and making repots and reviewing data. • Responsible to following GLP complaints towards data release and Lab maintenance. • Helping the team to do monthly calibration of LCMS and UPLC, HPLC. . Making the documents and reports as per GLP system. Show less



DuPont

• United States
• Manufacturing
• 700 & Above Employee

• Research Associate

  • Jun 2014 - Feb 2016

  Supporting to industrial Biotechnology team to characterize large molecules as well as small molecules. Amino Acids analysis from food, protein and fermentation samples by UPLC, GCMS  Oligosaccharides linkages identification, flavonoid identification by LCMS (LC-ESI-TQD)  Oligosaccharide analysis and quantification by HPAEC-PAD.  Fatty acid analysis by GCMS.  Large molecules (Molecular weight, protein sequencing determination) characterization by LC ESI Q-TOF.  TEA, TMA analysis from food materials by GC-FID. Show less



Syngene International Limited

• India
• Research Services
• 700 & Above Employee

• Jr.Manager

  • Feb 2012 - Jun 2014

  1. Involved in technical analysis as well as documentation review of method familiarization, method transfer and stability studies of different projects 2. Handled complete verification activity of Erythropoietin 3. As a group lead handled in process and finished product of PTH project 4. Involved three (Glatiramer acetate, Rituximab, and Cetuximab) different projects analytical validation. Quantification of mAb (monoclonal Antibodies) (DS & DP) by UV Spectroscopy. • Purity determination of IgG by CGE (CE) (PA800). • Conformational studies of EPO by CZE (PA800) • Moisture analysis of DP &DS Samples by KFCT • Method development for pI determination of IgG (mAb) by ICE 280. • Identifying, N-terminal sequencing of proteins, peptide sequencing, identifying PTM by MALDI-TOF-TOF & LCMS (HCTultra ETD II). • Method Development and Validation of average molecular weight determination of GA by SEC-MALDI. • Validation of Rituximab by SEC & CGE • Supporting for Inprocess and DS &DP analysis of rPTH by SE, RP-HPLC • Protein secondary & tertiary structure determination by CD spectroscopy. Other Responsibilities: • IOP & SOP, Installations, IQ, OQ, DQ preparations & reviewing according to cGMP rules and ICH guidelines. • MOA, ODS preparations and reviewing the data. • All HPLC Calibrations. • Familiarized Change Controls, Deviation, and OOS & OOT rising. • Daily & monthly calibrations of all small instruments like. Balances, pH meters etc. Show less



Sandor Speciality Diagnostics Pvt. Ltd.

• India
• Biotechnology Research
• 1 - 100 Employee

• Sr.Research officer

  • Jan 2009 - Feb 2012

  Characterization, method development, Validation of Protein, Amino acid analysis (from body fluids and etc) by RP-HPLC, SE-HPLC (Agilent1200 and waters 2695).  Proteome studies, Differential Expression, Characterization of the proteins by 2D-Gel Electrophoresis and 2D-DIGE.  Identifying, N-terminal sequencing of proteins, peptide sequencing & Phosphorylation studies by MALDI-TOF-MS and polysaccharides studies by MALDI –TOF TOF Characterization, method development, Validation of Protein, Amino acid analysis (from body fluids and etc) by RP-HPLC, SE-HPLC (Agilent1200 and waters 2695).  Proteome studies, Differential Expression, Characterization of the proteins by 2D-Gel Electrophoresis and 2D-DIGE.  Identifying, N-terminal sequencing of proteins, peptide sequencing & Phosphorylation studies by MALDI-TOF-MS and polysaccharides studies by MALDI –TOF TOF



Biological E. Limited

• India
• Pharmaceutical Manufacturing
• 700 & Above Employee

• Analytical Project trainee

  • May 2008 - Oct 2008

  Characterizing vaccines (HPLC, SDS-PAGE and Western Blott) by different analytical technicques. Characterizing vaccines (HPLC, SDS-PAGE and Western Blott) by different analytical technicques.