Priscylla Guimarães Migueres
Ph.D. Candidate at Instituto de Ciências Biomédicas da Universidade de São Paulo (ICB-USP)- Claim this Profile
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Bio
Experience
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Institute of Biomedical Sciences - University of Sao Paulo
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Brazil
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Higher Education
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100 - 200 Employee
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Ph.D. Candidate
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Apr 2019 - Present
- Investigation of the repositioning of traditional drugs and new compounds as potential therapeutic strategies for the treatment of bacteria that cause hospitalizations, aiming at reducing hospitalization costs, chronicity, and mortality of the infection; - Optimization of in vitro assays for the analysis of different response characteristics of compounds, resulting in a reduction in the use of reagents and plastic consumables by 80.1% of the initial value; - Presentations of results in meetings with project collaborators (pharmacists, chemists, and pharmaceutical industry) and in congresses at the university; - Search for scientific articles in various databases, analysis of scientific evidence, and technical-scientific writing of report and thesis; - Coordination of undergraduate students, introducing them to good laboratory practices and helping with the execution of tasks and experiments; - Optimized and validated different protocols for project development, building the first line of investigation for bacteriology within the laboratory, using High-throughput Screening (HTS) and High-Content Screening (HCS) techniques; - Cultivation and maintenance of bacteria and antimicrobial susceptibility test; - Maintenance of human lineage cell culture and cytotoxicity assays with drug candidates; - Molecular biology assays (PCR, electrophoresis, qRT-PCR); - Maintenance of an online laboratory management platform; - Critical analysis and processing of results; - Data analysis and biostatistics software: GraphPad Prism, TIBCO Spotfire, Microsoft Office (Excel); - Structuring of the laboratory following RDC 512/2021; - Financial management of project resources for purchasing reagents, inputs, and consumables, performing cost estimation analysis, considering the finances for acquiring materials, and rendering of accounts to the financing regulatory agencies. Show less
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Federal University of Rio de Janeiro
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Brazil
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Higher Education
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700 & Above Employee
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Master's degree
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Aug 2016 - Feb 2019
Evaluation of intestinal microbiota modulation in mice. Handling laboratory animals (mice), behavioral tests analysis, maintenance of probiotic starter culture, and molecular biology (qPCR) assays. Workshop organizer. Software: GraphPad prism and Microsoft Office.Master's thesis development.
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Undergraduate research
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Aug 2012 - Jul 2016
Phenotypic, molecular, and epidemiological characterization of multiresistant bacterial samples. Antibiotic susceptibility testing (AST), and molecular biology assays (PCR). Presentation and discussion of results in national congresses. Software: Microsoft Office. Degree project development.
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Laboratório Rio de Janeiro LTDA - Grupo Eságua
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Rio de Janeiro e Região, Brasil
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Internship
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Jan 2015 - Apr 2015
Physical, Chemical and Microbiological assays in water samples, after water treatment. Validation and confirmation of treatment results. Physical, Chemical and Microbiological assays in water samples, after water treatment. Validation and confirmation of treatment results.
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Education
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Invitare Pesquisa Clínica
Professional Training at Clinical Research, Clinical Research -
Gcell Cultivo 3D
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Unifesp - Universidade Federal de São Paulo
Ph.D. student, Microbiology and Immunology -
UFRJ - Universidade Federal do Rio de Janeiro
Master's degree, Microbiology -
UFRJ - Universidade Federal do Rio de Janeiro
Major, Biology - Microbiology and Immunology