Postdoctoral Scholar

• Oct 2020 - Present

• Engineered iPSC-NK cells to express AML CARs, and cytokines and establish gene knockouts using multiple strategies like safe harbor locus insertion, transposon, CRISPR/Cas9, and lentivirus. • Developed antisense oligonucleotide-mediated knockdown of hypoxia-related gene in immune cells (macrophages and NK cells) to overcome TME-mediated immunosuppression in vitro and in vivo via virus-like particles (VLPs). • Established an optical genome mapping platform collaboratively to determine genetic fitness/aberrations in engineered cell lines. Show less

Review Editor

• Aug 2023 - Present

Review Editor

• Aug 2023 - Present

Research Assistant

• Jan 2020 - Sep 2020

Ph.D. candidate

• Aug 2012 - Dec 2019

· Established novel transcription factor-mediated reprogramming platforms to generate astrocytes, microglia, and neural stem cells from somatic cells for neurodegenerative disease modeling (2013-2016)· Developed novel directed differentiation strategy to create airway epithelium from human iPSCs and specifically characterize pulmonary neuroendocrine cells using transcriptomics (2017-2020)· Developed a combination approach using single-cell RNA sequencing and antisense oligonucleotide treatment to improve human endoderm differentiation (2017-2020) Show less

Graduate Research Student

• Nov 2011 - Jul 2012

• Therapeutic targeting of Breast Cancer Stem Cells • Testing the efficiency of Mahanine & Withanolide-D, two plant-derived alkaloid components, as adjuvant therapy in addition to the existing chemotherapy in treating breast cancer patients • Correlation of different HLA I and II alleles and susceptibility of Breast Cancer in Eastern India • Therapeutic targeting of Breast Cancer Stem Cells • Testing the efficiency of Mahanine & Withanolide-D, two plant-derived alkaloid components, as adjuvant therapy in addition to the existing chemotherapy in treating breast cancer patients • Correlation of different HLA I and II alleles and susceptibility of Breast Cancer in Eastern India

Masters Candidate

• 2008 - 2010

• Engineered tobacco plants to be used as a biofactory expressing mouse interferon-gamma. • Engineered salt-stress tolerant rice variety. • Engineered tobacco plants to be used as a biofactory expressing mouse interferon-gamma. • Engineered salt-stress tolerant rice variety.