Experience

Ludger Limited

• United Kingdom
• Biotechnology Research
• 1 - 100 Employee

• Senior Scientist

  • Apr 2018 - Present

  Research, development and analytical services scientist: Wide experience in glycan and glycoprotein characterisation techniques involving (U)HPLC, LC-ESI-MS, MALDI-MS and high-throughput plate-based assays. Experience with analytical methods development, product development pipeline and analytical assay validation according to industry standards. Wide experience in profiling of glycoprotein therapeutics (monoclonal antibodies (mAb), fusion proteins, EPO, FSH) as well as biological and clinical samples (cell lines, blood, protein isolates). Familiar with advanced data processing techniques: data cleaning and pre-processing, exploratory data analysis, statistics and data modelling using machine learning techniques. Communicating results with non-technical team members.Coordination of external collaborative projects, supervision of more junior members of staff. Involvement in every step of client experience as a Principal Investigator in multiple commercial and academic projects: Writing commercial study proposals, sample processing, data processing and interpretation, writing reports and interacting with clients on a technical level.

• Research Scientist

  • Jun 2013 - Mar 2018

  Research and development into new glycotechnology: Expertise in chemical and enzymatic glycan release methodology, glycan derivatization (fluorophore tagging, permethylation) and analysis using mass spectrometry and chromatographic techniques. Profiling of glycans, glycopeptides and monosaccharides using (U)HPLC, LC-ESI-MS, MALDI-MS and high-throughput plate-based assays. Translation of diagnostic assays based on glycosylation features into clinical/ commercial tests (diagnostics of MODY type diabetes patients, GlycanAge service). Application of glycosylation analysis techniques in profiling of glycoprotein therapeutics (monoclonal antibodies (mAb), EPO, FSH) as well as human blood and saliva.



Institute of Immunology and Experimental Therapy, Polish Academy of Sciences

• Laboratory Research Assistant

  • 2011 - 2013

  Study on Klebsiella pneumoniae bacteriophage tail protein. Protein expression and purification. Activity tests on bacterial exopolysaccharides. Phage culturing. Study on Klebsiella pneumoniae bacteriophage tail protein. Protein expression and purification. Activity tests on bacterial exopolysaccharides. Phage culturing.