Paul Schwein

Project Lead at LabXchange
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Contact Information
Location
Cambridge, Massachusetts, United States, US

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Bio

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Experience

    • United States
    • E-Learning Providers
    • 1 - 100 Employee
    • Project Lead
      • Aug 2022 - Present
    • Research Assistant
      • Jun 2016 - Present

      My graduate work examines how human cells use the intracellular glycan O-linked N-acetyl glucosamine (O-GlcNAc) as a post-translational modification to communicate nutrient availability across disparate signaling pathways. Similar to phosphorylation, O-GlcNAc is reversibly installed onto proteins. Its presence or absence on a protein may affect subsequent phosphorylation events at nearby residues. My work examines the promiscuous protein kinase CK2, and how glycosylation of its alpha subunit affects substrate specificity. Show less

    • United States
    • Higher Education
    • 700 & Above Employee
    • Research Assistant
      • Oct 2013 - Mar 2022

      I partook in undergraduate research for three years at MIT in three different labs. Each taught me my first lessons in bacterial cloning, molecular biology, cell culture, and working with various model organisms, such as C. elegans, A. thaliana, and several human cell lines including mesenchymal stem cells. These foundational years of research training set the stage for my successful internship at Novartis, and in graduate school. I partook in undergraduate research for three years at MIT in three different labs. Each taught me my first lessons in bacterial cloning, molecular biology, cell culture, and working with various model organisms, such as C. elegans, A. thaliana, and several human cell lines including mesenchymal stem cells. These foundational years of research training set the stage for my successful internship at Novartis, and in graduate school.

    • United States
    • Pharmaceutical Manufacturing
    • 700 & Above Employee
    • Scientific Summer Scholar
      • Jun 2015 - Aug 2015

      This ten-week summer internship program with Novartis exposed me to the pharmaceutical industry and the drug development process. My work utilized my already strong skills in cell culture and molecular biology, and gave me new experience with high-throughput screening and analysis of large datasets. This ten-week summer internship program with Novartis exposed me to the pharmaceutical industry and the drug development process. My work utilized my already strong skills in cell culture and molecular biology, and gave me new experience with high-throughput screening and analysis of large datasets.

    • United States
    • Education Administration Programs
    • 1 - 100 Employee
    • Science Specialist
      • Jun 2013 - Aug 2013

      Developed and executed educational activities in the sciences for children ages 3-12 at Camp Sagemont. Received outstanding feedback and formative experience in educating and engaging younger audiences. Developed and executed educational activities in the sciences for children ages 3-12 at Camp Sagemont. Received outstanding feedback and formative experience in educating and engaging younger audiences.

Education

  • Harvard University Graduate School of Arts and Sciences
    Doctor of Philosophy - PhD, Chemical Biology
    2016 - 2022
  • Massachusetts Institute of Technology
    Bachelor of Science - BS, Biology, General
    2012 - 2016
  • Cypress Bay High School
    9-12
    2009 - 2012

Community

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