Paul Schwein
Project Lead at LabXchange- Claim this Profile
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Bio
Experience
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LabXchange
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United States
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E-Learning Providers
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1 - 100 Employee
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Project Lead
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Aug 2022 - Present
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Research Assistant
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Jun 2016 - Present
My graduate work examines how human cells use the intracellular glycan O-linked N-acetyl glucosamine (O-GlcNAc) as a post-translational modification to communicate nutrient availability across disparate signaling pathways. Similar to phosphorylation, O-GlcNAc is reversibly installed onto proteins. Its presence or absence on a protein may affect subsequent phosphorylation events at nearby residues. My work examines the promiscuous protein kinase CK2, and how glycosylation of its alpha subunit affects substrate specificity. Show less
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Massachusetts Institute of Technology
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United States
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Higher Education
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700 & Above Employee
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Research Assistant
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Oct 2013 - Mar 2022
I partook in undergraduate research for three years at MIT in three different labs. Each taught me my first lessons in bacterial cloning, molecular biology, cell culture, and working with various model organisms, such as C. elegans, A. thaliana, and several human cell lines including mesenchymal stem cells. These foundational years of research training set the stage for my successful internship at Novartis, and in graduate school. I partook in undergraduate research for three years at MIT in three different labs. Each taught me my first lessons in bacterial cloning, molecular biology, cell culture, and working with various model organisms, such as C. elegans, A. thaliana, and several human cell lines including mesenchymal stem cells. These foundational years of research training set the stage for my successful internship at Novartis, and in graduate school.
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Novartis Institutes for BioMedical Research (NIBR)
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United States
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Pharmaceutical Manufacturing
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700 & Above Employee
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Scientific Summer Scholar
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Jun 2015 - Aug 2015
This ten-week summer internship program with Novartis exposed me to the pharmaceutical industry and the drug development process. My work utilized my already strong skills in cell culture and molecular biology, and gave me new experience with high-throughput screening and analysis of large datasets. This ten-week summer internship program with Novartis exposed me to the pharmaceutical industry and the drug development process. My work utilized my already strong skills in cell culture and molecular biology, and gave me new experience with high-throughput screening and analysis of large datasets.
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The Sagemont School
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United States
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Education Administration Programs
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1 - 100 Employee
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Science Specialist
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Jun 2013 - Aug 2013
Developed and executed educational activities in the sciences for children ages 3-12 at Camp Sagemont. Received outstanding feedback and formative experience in educating and engaging younger audiences. Developed and executed educational activities in the sciences for children ages 3-12 at Camp Sagemont. Received outstanding feedback and formative experience in educating and engaging younger audiences.
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Education
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Harvard University Graduate School of Arts and Sciences
Doctor of Philosophy - PhD, Chemical Biology -
Massachusetts Institute of Technology
Bachelor of Science - BS, Biology, General -
Cypress Bay High School
9-12