Patrick Gonyo

Senior Research Scientist at Nano RED | Precision Medicine in a Pandemic & Beyond
  • Claim this Profile
Contact Information
us****@****om
(386) 825-5501
Location
Madison, Wisconsin, United States, US

Topline Score

Topline score feature will be out soon.

Bio

Generated by
Topline AI

You need to have a working account to view this content.
You need to have a working account to view this content.

Experience

    • Biotechnology Research
    • 1 - 100 Employee
    • Senior Research Scientist
      • May 2022 - Present

      Developing a genome therapy delivery platform optimized to treat cancer and respiratory viruses. Developing a genome therapy delivery platform optimized to treat cancer and respiratory viruses.

    • United States
    • Hospitals and Health Care
    • 700 & Above Employee
    • Postdoctoral Research Fellow
      • Jul 2019 - Jul 2021

      Discovered that PKCi is necessary for transformed growth, migration, and clonal expansion of EGFR-mutant lung adenocarcinoma (LADC). Utilized a combination of bioinformatics and molecular biology approaches to identify and validate genetic signatures / biomarkers that predict sensitivity of EGFR-mutant LADC to pharmacologic inhibition of PKCi in known cells of origin of LADC. Developed protocols for ex vivo transformation of bronchioalveolar stem cells and alveolar type II cells with mutant EGFR in 3D culture, followed by orthotopic lung injection and establishment of lung tumors in mice. Show less

    • United Kingdom
    • Pharmaceutical Manufacturing
    • 1 - 100 Employee
    • Medical Writer
      • Apr 2019 - Jun 2019

      Developed and wrote scientific publications (abstracts, posters, oral presentations, and manuscripts) in close collaboration with authors and clients.Carried out all aspects of project management, including leading calls with authors and clients to align on content, writing and revising drafts according to author feedback, and finalizing publication.

    • Associate Medical Writer
      • Feb 2018 - Apr 2019

    • Higher Education
    • 700 & Above Employee
    • PhD Student - Dept. of Pharmacology and Toxicology
      • Aug 2010 - Jun 2017

      - Discovered that SmgGDS promotes malignancy through regulation of nucleolar stress and DREAM complex gene expression (resulted in one first author publication in Oncogene) - Co-discovered (2nd author) that prenylation of Rap1B is signal-dependent; findings were published as the cover article in Science Signaling and led to $1.7 million in funding - Strong leadership skills and experience managing several multi-laboratory collaborations simultaneously, resulting in six co-authored publications - Excellent communication skills, as demonstrated by presentations at two international scientific conferences (multiple poster awards) - Strong relationship building skills, as evidenced by training and mentoring several students in molecular biology techniques, assay development, and data analysis - Innovative and resourceful; developed methods previously not utilized by members of the laboratory, including Northern and Southern blotting, qPCR, flow cytometry, and confocal microscopy Show less

    • Higher Education
    • 700 & Above Employee
    • Research Technologist - Dept. of Microbiology and Immunology
      • Jun 2008 - Jun 2010

      - Established a foundation in molecular biology by investigating mechanisms utilized by viruses to evade detection by the host immune system (resulted in two co-authored publications) - Performed lab manager tasks to ensure efficient laboratory operation - Gained expertise in molecular biology techniques including cloning, PCR, radioactive pulse/chase, western blotting, microscopy, flow cytometry, cell culture, and viral transduction. - Established a foundation in molecular biology by investigating mechanisms utilized by viruses to evade detection by the host immune system (resulted in two co-authored publications) - Performed lab manager tasks to ensure efficient laboratory operation - Gained expertise in molecular biology techniques including cloning, PCR, radioactive pulse/chase, western blotting, microscopy, flow cytometry, cell culture, and viral transduction.

Education

  • Medical College of Wisconsin
    Doctor of Philosophy - PhD, Pharmacology and Toxicology (Cancer Biology)
    2010 - 2017
  • Carroll University
    Bachelor of Science - BS, Biology, General
    2004 - 2008

Community

You need to have a working account to view this content. Click here to join now