Patricia Riedlova
Marie Curie Early Stage Researcher at University of Glasgow, College of Medical, Veterinary and Life Sciences- Claim this Profile
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Slovak Native or bilingual proficiency
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Czech Native or bilingual proficiency
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German Elementary proficiency
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English Full professional proficiency
Topline Score
Bio
Credentials
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Excel 2019 Essential Training
LinkedInApr, 2020- Nov, 2024 -
IELTS
IELTS BRITISHCOUNCILApr, 2017- Nov, 2024
Experience
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University of Glasgow, College of Medical, Veterinary and Life Sciences
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United Kingdom
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100 - 200 Employee
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Marie Curie Early Stage Researcher
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Jan 2020 - Present
My work focuses on osteoclasts which are bone-resorbing cells playing an important role in bone remodelling and rheumatoid arthritis. Under physiological conditions, these cells are in balance with bone-forming osteoblasts, however, when homeostasis is perturbed, it can lead to excessive bone resorption such as that seen in rheumatoid arthritis. In my project, I investigate the role of specialised pro-resolving mediators (SPMs; lipids biosynthesisesed from fatty acids during acute inflammation). These lipids are believed to restore homeostasis, prevent bone resorption, repair bone/cartilage, reduce inflammation, pain, and swelling in patients with rheumatoid arthritis. The aim of my project is to investigate the effect of these lipids on osteoclasts, identify SPM receptors present on mature osteoclasts, and elucidate signalling pathways via which we could better understand the role in osteoclastogenesis and resolution of inflammation. This work is a part the ArthritisHeal project consisting of 12 early-stage researchers (ESRs) funded by the EU's Horizon 2020 research and innovation programme under the Marie Skłodowska-Curie Grant (ArthritsHeal website attached). Show less
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Leiden University Medical Center
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Netherlands
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Hospitals and Health Care
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700 & Above Employee
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ArthritisHeal collaboration (PhD secondment)
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Oct 2021 - Dec 2021
PhD secondment at the Department of Parasitology as a part of an ArthritisHeal collaboration. My work was focused on the metabolism of osteoclasts differentiated from healthy monocytes or monocytes isolated from patients with active rheumatoid arthritis. The focus was on the regulation of metabolism by specialised pro-resolving mediators and comparing the changes between monocytes, macrophages, and osteoclasts. PhD secondment at the Department of Parasitology as a part of an ArthritisHeal collaboration. My work was focused on the metabolism of osteoclasts differentiated from healthy monocytes or monocytes isolated from patients with active rheumatoid arthritis. The focus was on the regulation of metabolism by specialised pro-resolving mediators and comparing the changes between monocytes, macrophages, and osteoclasts.
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Education
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Aalborg Universitet
Master of Science in Engineering (MScEng), Medical Biotechnology -
Slovenská technická univerzita v Bratislave
Bachelor's degree, Chemistry, medical chemistry and chemical materials -
Columbus High School, Columbus, Texas
Year abroad, GCE Advanced Level (all A's) -
Gymnazium Bilikova, Bratislava, Slovakia
Maturita, Bilingual studies