Pankti Thakkar
Associate Research Scientist at Kephera Diagnostics- Claim this Profile
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Bio
Experience
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Kephera Diagnostics
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United States
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Biotechnology Research
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1 - 100 Employee
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Associate Research Scientist
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Aug 2023 - Present
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Graduate Research Assistant
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Jan 2021 - Sep 2023
• Developed Enzymatically Signal Enhanced Lateral Flow Assay Test for HIV detection using p24 antigen• Performed antibody screening for protein biomarkers using techniques like DLS, SDS Page, Octet, Dotblot, and Dipsticks• Improved the Limit of detection 10 folds by developing and using signal enhancement technique with HRP to be able to detect HIV as early as 17 days as opposed to the currently available commercial tests that detect at up to 90 days • Automated production of the sandwich assay lateral flow on the Biodot system for uniform scalability of optimized two-dimensional paper network (2DPN) device• Conducted original research, analyzed data, and synthesized findings to develop a rigorous thesis document• Demonstrated mastery of the subject matter and effective communication skills through conference presentations Show less
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Undergraduate Research Assistant
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Jan 2020 - Dec 2021
• Conducted research on point of care (POC) molecular diagnostic device, developing a non-invasive device for glucose detection in exhaled breath condensate (EBC)• Tested the stability of the glucose assay in response to altered the pH, salt, and ammonia concentrations in the EBC sample• Scripted IRB protocols and questionnaires and Composed the findings to write a manuscript that has been submitted for publication
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Selux Diagnostics, Inc
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United States
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Biotechnology Research
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1 - 100 Employee
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Research and development Co-op
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Aug 2020 - Aug 2021
• Executed experiments to develop and characterize a novel positive blood culture separation system for antibiotic susceptibility testing in six-month rotations for R&D and Manufacturing departments • Established protocols and modified formulations to eliminate AST data discrepancies for staphylococcus aureus clumping and reduced time to results by 40 minutes • Developed a proprietary scripting language to control the workflow for an automatic pipetting system to inoculate multiple 384-well-plates • Demonstrated effective leadership and communication by training and supervising two interns for preclinical trials and usability studies Show less
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Laboratory of implantable microsystems Research Purdue University
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west lafayette , Indiana Area
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Undergraduate Research Assistant
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Aug 2018 - Aug 2019
• Developed strategies and experimental set ups to test micro-fabricated magnetic actuators for body-like conditions to help cure neurological disorder Hydrocephalus • Analyzed SEM images of nanopillars and actuators incubated in bacteria using software Fiji/imageJ and Imaris • Developed strategies and experimental set ups to test micro-fabricated magnetic actuators for body-like conditions to help cure neurological disorder Hydrocephalus • Analyzed SEM images of nanopillars and actuators incubated in bacteria using software Fiji/imageJ and Imaris
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Indian Institute of Technology Gandhinagar
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India
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Higher Education
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700 & Above Employee
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Process Engineering Intern
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May 2019 - Jul 2019
• Designed and conceptualized a user-centered low-risk modality virtual reality game for use in stroke rehabilitation that can be used at home as a physical therapy alternative • Built an analog circuit to record physiological signals using resistive and capacitive circuits • Surveyed 85 clients, physicians, physical therapists, and patients to optimize the product utility • Designed and conceptualized a user-centered low-risk modality virtual reality game for use in stroke rehabilitation that can be used at home as a physical therapy alternative • Built an analog circuit to record physiological signals using resistive and capacitive circuits • Surveyed 85 clients, physicians, physical therapists, and patients to optimize the product utility
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UML Perfect Biomedia Pvt. Ldt
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Gujarat, India
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Summer Intern
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May 2018 - Aug 2018
• Conducted sterile cell culture and molecular biological assays including DNA isolation, DNA sequencing, PCR amplification, and Western blots • Led experiments focusing on the identification, isolation, and detection of different types of bacteria • Designed troubleshooting and maintenance activities to minimize the cost of safety instruments by collaborating with the safety team • Conducted sterile cell culture and molecular biological assays including DNA isolation, DNA sequencing, PCR amplification, and Western blots • Led experiments focusing on the identification, isolation, and detection of different types of bacteria • Designed troubleshooting and maintenance activities to minimize the cost of safety instruments by collaborating with the safety team
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Education
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Purdue University
Master of Science - MS, Biomedical/Medical Engineering -
Purdue University
Bachelor's of science, Biomedical/Medical Engineering