Experience

Lygos

• United States
• Chemical Manufacturing
• 1 - 100 Employee

• Scientist III

  • Feb 2021 - Present

  Berkeley, California, United States Process Scientist in the Downstream Processing Department. Tasked with the R&D and scale up for the isolation, derivatization, and purification of target products from fermentation broths.

• Scientist II

  • Apr 2018 - Feb 2021

  San Francisco Bay Area Process Scientist in the Downstream Processing Department. Tasked with the R&D and scale up for the isolation, derivatization, and purification of target products from fermentation broths.



AMPAC Fine Chemicals

• United States
• Pharmaceutical Manufacturing
• 300 - 400 Employee

• Process Scientist II

  • Jan 2015 - Mar 2018

  Rancho Cordova Process R&D Chemist experienced in improving and implementing a process on lab, kilo, and 100+ kg scales, and providing API production support to the plant. ● Lead chemist on multiple concurrent projects. ● Successfully scaled up multiple projects from gram scale to kg, >10 kg, and >100 kg scale ● Completed extensive Design of Experiment (DOE) projects on a customer tech transfer to provide optimization and ranging data. ● Evaluated and demonstrated the safety of acidic… Show more Process R&D Chemist experienced in improving and implementing a process on lab, kilo, and 100+ kg scales, and providing API production support to the plant. ● Lead chemist on multiple concurrent projects. ● Successfully scaled up multiple projects from gram scale to kg, >10 kg, and >100 kg scale ● Completed extensive Design of Experiment (DOE) projects on a customer tech transfer to provide optimization and ranging data. ● Evaluated and demonstrated the safety of acidic azide reactions through monitoring of both solution and headspace concentrations for hydrazoic acid. Implemented engineering controls in the reaction process to further safeguard against incidents. ● Experienced working with energetic, high potency, toxic, and controlled substances using the appropriate PPE and documentation (i.e. airline respirators, chemical resistant suits, blast shields). ● Trained in cGMP with experience in both advising Operations personnel and personal handling of API ● Support plant production through new material use tests, front runs of plant material to ensure product quality, and direct plant support. ● Advise Operational and Engineering staff during and prior to production on what to expect and how to proceed, evaluating both safety and process quality. ● Coordinate regularly between Project Management, Quality Assurance, Regulatory Affairs, Analytical Chemistry, Engineering, EH&S, and Operations to ensure projects are advancing efficiently, safely, and on schedule. ● Experienced writing technical documents: Controlled Parameters Reports, Master Batch Records, MBR Comment Sheets, Change Controls, Variance Reports, Root Cause Analyses, Weekly Reports/Updates (internal & external), Process R&D Reports, and Experimental Designs. ● Communicate with customers to update process progress, determine priorities, and discuss additional lab experiments to perform. ● Detail-oriented process evaluation has prevented potential equipment damage not anticipated by customer. Show less



University of Pittsburgh

• United States
• Higher Education
• 700 & Above Employee

• Graduate Student Researcher

  • Aug 2010 - Dec 2014

  Pittsburgh, PA I worked under Dennis Curran studying natural product synthesis and fluorous mixture synthesis. ● Developed novel fluorous tagging reagents and proved efficacy for HPLC separation during fluorous mixture synthesis ● Optimized formation of thionocarbonates for use in subsequent radical deoxygenation reactions ● Synthesized late-stage precursor to (4S,8S,12S)-4,8,12,-trimethylnonadecanol and other oligoisoprenoids in high enantiopurity ● Evaluated the enantio- and… Show more I worked under Dennis Curran studying natural product synthesis and fluorous mixture synthesis. ● Developed novel fluorous tagging reagents and proved efficacy for HPLC separation during fluorous mixture synthesis ● Optimized formation of thionocarbonates for use in subsequent radical deoxygenation reactions ● Synthesized late-stage precursor to (4S,8S,12S)-4,8,12,-trimethylnonadecanol and other oligoisoprenoids in high enantiopurity ● Evaluated the enantio- and diastereoselectivities of catalytic and stoichiometric reagents through the use of chiral GC and 13C NMR data Show less