Experience

Khon Kaen University

• Thailand
• Higher Education
• 200 - 300 Employee

• Lecturer at Faculty of Engineering

  • Jun 2018 - Present



Duke University

• United States
• Higher Education
• 700 & Above Employee

• Postdoctoral Research Associate

  • Jan 2016 - Jul 2017

  Areas: Tissue engineering, drug delivery, biological transport, spectroscopy and imaging, nanotechnology• Development of a 3D microscale tissue-engineered blood vessel (TEBVs) from smooth muscle cells (SMCs) derived from induced pluripotent stem cells (iPSCs) for personalized cardiovascular medicine • Design of a nanoparticulate drug delivery formulation (liposome) that serves two functions: to deliver anti-HIV microbicide drugs to mucosal cells and to track diffusion of drugs in the mucosal tissue. • Development of a non-invasive horizontal assay for quantitative detection of anti-HIV drugs at deep tissue regions using Raman spectroscopy and optical coherence tomography. • Development of a computational modeling to improve understanding of key parameters that govern drug release kinetics in topical drug delivery from hydrogel formulations. • Mentoring undergraduate and graduate students on various BME projects in the lab. Show less

• Graduate Teaching Assistant

  • Aug 2013 - Dec 2015

  BME 528: Biofluid Mechanics (graduate-level)BME 563: Transport Processes in HIV Transmission and Prevention (graduate-level)BME 394: Projects in Biomedical EngineeringBME 493: Projects in Biomedical EngineeringBME 494: Projects in Biomedical Engineering• Holding weekly problem sessions• Preparing grading schemes/solutions and grading weekly assignments• Holding lectures/review sessions per instructor’s request• Mentoring students on their independent study research projects in BME. Show less

• Graduate Research Assistant

  • Aug 2010 - Dec 2015

  Areas: Drug delivery, biofluid mechanics, spectroscopy and imaging, pharmaceutical engineering, mathematical modeling, HIV prevention • Development of real-time, label-free assays using biomedical spectroscopy and imaging techniques, i.e., confocal Raman spectroscopy (CRS) and spectral-domain optical coherence tomography (SD-OCT), to non-invasively monitor and analyze the integrity of ex vivo mucosal vaginal and rectal tissues following anti-HIV hydrogel treatment.• Detection and quantification of anti-HIV drug spatiotemporal distributions and transport properties in the delivery hydrogel vehicles and the mucosal tissues in custom transport chambers.• Translation of the spatiotemporal drug concentration distributions within microbicide hydrogels and tissues into fundamental transport properties, e.g., the drug diffusion and partition coefficients. These transport parameters are input to deterministic compartmental models of drug delivery in order to help understand and predict salient factors that govern microbicide functionality for prevention of sexually-transmitted HIV infections.• Characterization of the rheological properties and the mucosal tissue coating by various microbicide drug delivery formulations designed for vaginal and rectal microbicide drug delivery, including hydrogels and quick-dissolving films. • Investigation of effects of dilution with ambient vaginal fluid on the rheological properties, vaginal luminal deployment and drug release into vaginal mucosal tissues of anti-HIV microbicide drug delivery formulations. • Design of new liposomal formulations for vaginal and rectal delivery of anti-HIV microbicide drugs. Show less

• Pratt Engineering Research Fellow

  • Sep 2008 - Aug 2010

  Research Topics: 1. Development of Cisplatin-loaded lysolipid-containing temperature sensitive liposomes for optimized loading efficiency and release by hyperthermia2. Liposome-mediated release of Mn porphyrin based cellular redox modulator: comparison of two Mn porphyrins of different lipophilicitiesAreas: Controlled drug delivery systems, nanoparticle drug delivery, liposome technology, biomaterials, cancer therapy Advisor: Professor David Needham, Ph.D.• Development and formulation of Low Temperature-Sensitive Liposomes (LTSL) loaded with a chemotherapeutic agent, cisplatin, for cancer targeted drug delivery. • Design of a new liposome-based drug delivery system which is triggered under hyperthermia for two potent Metalloporphyrin-based mediators of oxidative stress injuries.• Optimization of anti-cancer drug loading efficiency of the liposomes through a novel encapsulation method.• Investigation and characterization of the stability and leakage of the formulated temperature-sensitive liposomes at the physiological temperature.• Analysis of the release kinetics of the formulated temperature-sensitive liposomes in biological fluids, following mild hyperthermia application (i.e., at the transition temperature of lipids). Show less