Experience

BiosanaPharma

• Netherlands
• Biotechnology Research
• 1 - 100 Employee

• Lead Program Manager Drug Development

  • Feb 2020 - Present

  Keywords: program management of clinical-stage biotechnology company, CMC / regulatory strategy, continuous manufacturing of monoclonal antibodies, Biosana 3C process, analytical method development, biosimilars, omalizumab. Keywords: program management of clinical-stage biotechnology company, CMC / regulatory strategy, continuous manufacturing of monoclonal antibodies, Biosana 3C process, analytical method development, biosimilars, omalizumab.



Intravacc

• Netherlands
• Biotechnology Research
• 1 - 100 Employee

• Program Manager

  • Jun 2019 - Jan 2020

  Program management and acquisition of R&D and CMC bacterial vaccine projects (outer membrane vesicles, glycoconjugates, LPS adjuvants).

• Project Lead

  • Jul 2017 - Sep 2019

  Project management of R&D and CMC projects within the viral vaccine program.Keywords: viral vaccines, enteroviruses, poliovirus, Sabin IPV, Vero cell platform, animal-component-free production, GMP, seed lots, process and analytical development, preclinical studies, QC, QA, RA, project and account management.



Janssen Prevention Center, Janssen Vaccines & Prevention B.V.

• Leiden

• Scientist

  • Aug 2015 - Jun 2017

  Activities and interests: R&D, line management, coordination of preclinical studies, mucosal (intestinal) immunology, gut microbiome, bacterial vaccines. Activities and interests: R&D, line management, coordination of preclinical studies, mucosal (intestinal) immunology, gut microbiome, bacterial vaccines.



Leiden University Medical Center

• Netherlands
• Hospitals and Health Care
• 700 & Above Employee

• Postdoctoral Researcher

  • Sep 2010 - Jul 2015

  Department of Parasitology Keywords: helminths, schistosomiasis, glycobiology, glyco-immunology, structure-function aspects of glycans, immune modulation. Experience in a broad range of laboratory skills, e.g. glycan analysis by mass spectrometry, protein purification, cell culturing, immune assays, and in vivo studies. Projects: • Immunization and vaccination studies using glycoconjugates and anti-glycan antibodies. • Immune modulation by native, secreted/excreted or recombinantly produced helminth molecules (e.g. to discover anti-inflammatory products), comprising screening on immune cells, protein purification and identification, and glycosylation analysis. • The role of glycans in immunopathology of schistosomiasis (i.e. granuloma formation in liver induced by the parasite's eggs). Including working visit to Tufts University in Boston, USA (November 2013). Show less



Amsterdam UMC

• Netherlands
• Hospitals and Health Care
• 700 & Above Employee

• PhD student

  • Jun 2006 - Aug 2010

  Department of Medical Microbiology and Infection Control Title project: Immunomodulation by mycobacteria. Thesis title: Sugar caps of mycobacteria: virulence factors or decorative elements? Keywords: tuberculosis, TB, Mycobacterium tuberculosis, Mycobacterium bovis BCG vaccine, Mycobacterium marinum, cell wall glycolipids, biosynthesis, immune modulation, host-pathogen interactions, C-type lectins, dendritic cells. Department of Medical Microbiology and Infection Control Title project: Immunomodulation by mycobacteria. Thesis title: Sugar caps of mycobacteria: virulence factors or decorative elements? Keywords: tuberculosis, TB, Mycobacterium tuberculosis, Mycobacterium bovis BCG vaccine, Mycobacterium marinum, cell wall glycolipids, biosynthesis, immune modulation, host-pathogen interactions, C-type lectins, dendritic cells.



University of Glasgow

• United Kingdom
• Higher Education
• 700 & Above Employee

• Internships

  • 2003 - 2006

  Three research internships of half a year each at different locations: at the department of Structural Biology and at the department of Molecular Cell Physiology of the VU University Amsterdam, and at the department of Infection and Immunity at the University of Glasgow, UK. Research fields: molecular biology, systems biology, and microbial ecology. Three research internships of half a year each at different locations: at the department of Structural Biology and at the department of Molecular Cell Physiology of the VU University Amsterdam, and at the department of Infection and Immunity at the University of Glasgow, UK. Research fields: molecular biology, systems biology, and microbial ecology.



Vrije Universiteit Amsterdam (VU Amsterdam)

• Netherlands
• Higher Education
• 700 & Above Employee

• Computing Service

  • 2000 - 2006

  Faculty of Earth & Life Sciences Tasks: maintaining the helpdesk website, writing of manuals, service support. Faculty of Earth & Life Sciences Tasks: maintaining the helpdesk website, writing of manuals, service support.