Nivruthi Shekar

Post Graduate research Student at Perth Biodesign
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Contact Information
us****@****om
(386) 825-5501
Location
East Perth, Western Australia, Australia, AU

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Credentials

  • Space medicine
    Duke University
    Jun, 2022
    - Sep, 2024
  • Biomedical Visualisation
    university of glassgow coursera
    Oct, 2020
    - Sep, 2024
  • Data Science in Stratified Healthcare and Precision Medicine
    university of edinburgh coursera
    Oct, 2020
    - Sep, 2024
  • Healthcare Entrepreneurship: Taking Ideas to Market
    Imperial college London coursera
    Sep, 2020
    - Sep, 2024
  • Global health policy
    university of tokyo coursera
    Aug, 2020
    - Sep, 2024
  • A crash course on data science
    john hopkins university Coursera
    Jul, 2020
    - Sep, 2024
  • Essential epidemiologic tools for public health practice
    Coursera
    Jul, 2020
    - Sep, 2024

Experience

  • Perth Biodesign
    • Australia
    • Higher Education
    • 1 - 100 Employee
    • Post Graduate research Student
      • Jun 2023 - Present
  • The University of Western Australia
    • Australia
    • Higher Education
    • 700 & Above Employee
    • Exchange Student
      • Mar 2023 - Present

      Bioprospecting herbal compounds as potential anticancer drugs - Breast cancer has been the most common form of cancer among women globally. Given that the majority of chemotherapeutic medications are associated with cancer metastasis, drug tolerance, and adverse health effects, researchers are searching for more effective breast cancer preventative and curative options. Recent reports shows that dysregulation of Notch signaling pathway promotes resistance to targeted cytotoxic therapies. Preclinical studies prove that targeting the notch pathway can reverse the resistance mechanism through elimination of mutated breast stem cells. Notch inhibitors have yet to be clinically approved mainly due to dose limiting gastro-intestinal toxicity. When compared to commercially available synthetic pharmaceuticals such as Tamoxifen, doxorubicin, letrozole, herbal drugs have far less adverse effects and are less hazardous since they include phytochemicals with active bio compounds that inhibits reduction in tumor cell apoptosis.A promising strategy is the identification of notch downstream targets that are specifically expressed in breast tumors as biomarkers for prognosis. In order to develop a novel breast cancer therapy approach, this research will focus on identification of herbal compounds as potential anticancer drugs especially for breast cancer. In-silico analysis and protein docking will help in characterization and ranking the selected bio-compound as efficient inhibitors for precise carcinomic cell growth control. Show less

  • Sri Ramakrishna Engineering College
    • India
    • Higher Education
    • 300 - 400 Employee
    • Postgraduate Student
      • Nov 2021 - May 2023

Education

  • The University of Western Australia
    International exchange program, School of Agriculture and Environment
    2023 - 2023
  • PSG College of Technology
    BE - Bachelor of Engineering, Biomedical/Medical Engineering
    2016 - 2020
  • Sri Ramakrishna Engineering College
    Master of Technology - MTech, Nanoscience and Technology
    2021 - 2023
  • Annamalai University
    Bachelor of Fine Arts - BFA, Bharathanatyam
    2019 - 2023
  • vidya Vikas matric higher secondary school
    12th grade
    2014 - 2016
  • kotagiri public school
    10th grade
    2009 - 2014

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