Nathaniel Mahieu

Senior Scientist II at EmpressTx
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Location
Cambridge, Massachusetts, United States, US

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Experience

    • United Kingdom
    • Investment Management
    • Senior Scientist II
      • Aug 2022 - Present

      Bridging experimental methodology and data analysis> Omics - chemoproteomics TPP photoaffinity, metabolomics, natural products, structure elucidation, mass spectrometry> Data - R, Nextflow, Knitr, Docker, AWS S3/EC2/Batch, pipeline building, inference making

    • Senior Scientist
      • Dec 2021 - Aug 2022

    • Senior Scientist, Metabolomics
      • Jun 2021 - Dec 2021

      Thermo Vanquish Neo, Orbitrap Astral, Eclipse, Exploris, Agilent 6560 QTOF, Nanoflow, Analytical flow, UHPLC, LC/MS Compound Discoverer, XCMS, Proteome Discoverer, Biognosis Spectromine, Spectronaut Thermo Vanquish Neo, Orbitrap Astral, Eclipse, Exploris, Agilent 6560 QTOF, Nanoflow, Analytical flow, UHPLC, LC/MS Compound Discoverer, XCMS, Proteome Discoverer, Biognosis Spectromine, Spectronaut

    • South Africa
    • Non-profit Organizations
    • Consultant, Algorithm Development
      • Jun 2019 - Jun 2021

      Analysis pipeline for WSIM-MS2 data to recovering DNA adducts relevant to cancer initiation.

    • Consultant, Mass Spec Lab Deployment
      • Jun 2019 - Dec 2020

      Lab construction and high performance infrastructure

    • United States
    • Higher Education
    • 700 & Above Employee
    • Ph.D. Candidate
      • Jul 2011 - Jan 2017

      Patti Lab, Department of Chemistry and GeneticsSystems-Level Annotation of a Metabolomics Data Set Reduces 25,000 Features to Fewer than 1000 Metabolites (Mahieu, 2017)

    • Credentialing Kit for Metabolomics- Product Pioneering, Development, and Launch
      • Jul 2011 - Jan 2017

      Developed the "Credentialed E. coli Cell Extract Kit." Engaged commercial partner Cambride Isotope Labs to commercialize and market the kit through publications and lectures.

    • United States
    • Higher Education
    • 1 - 100 Employee
    • Research Assistant
      • May 2010 - May 2011

      Undergraduate thesis: study of hypoxia-activated chemotherapeutics, synthesis of a fluorescent chemical probe of cellular hypoxia.

    • Tutor, Total Person Program
      • Jun 2009 - May 2010

    • Israel
    • Pharmaceutical Manufacturing
    • 700 & Above Employee
    • Quality Control Analyst
      • May 2008 - Aug 2010

      GMP/ISO 9001 conformity, FDA compliant analytical testing and quality control for antibiotic APIs. GMP/ISO 9001 conformity, FDA compliant analytical testing and quality control for antibiotic APIs.

    • Photography and Web Development
      • 2005 - 2010

Education

  • Washington University in St. Louis
    PhD, Chemistry
    2011 - 2017
  • University of Missouri-Columbia
    BS Chemistry and BS with Honors Biochemistry
    2007 - 2011

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