Nathaniel Mahieu
Senior Scientist II at EmpressTx- Claim this Profile
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Bio
Experience
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Empress Therapeutics
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United States
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Biotechnology Research
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1 - 100 Employee
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Senior Scientist II
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Aug 2022 - Present
Bridging experimental methodology and data analysis> Omics - chemoproteomics TPP photoaffinity, metabolomics, natural products, structure elucidation, mass spectrometry> Data - R, Nextflow, Knitr, Docker, AWS S3/EC2/Batch, pipeline building, inference making
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Senior Scientist
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Dec 2021 - Aug 2022
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Senior Scientist, Metabolomics
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Jun 2021 - Dec 2021
Thermo Vanquish Neo, Orbitrap Astral, Eclipse, Exploris, Agilent 6560 QTOF, Nanoflow, Analytical flow, UHPLC, LC/MS Compound Discoverer, XCMS, Proteome Discoverer, Biognosis Spectromine, Spectronaut Thermo Vanquish Neo, Orbitrap Astral, Eclipse, Exploris, Agilent 6560 QTOF, Nanoflow, Analytical flow, UHPLC, LC/MS Compound Discoverer, XCMS, Proteome Discoverer, Biognosis Spectromine, Spectronaut
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Consultant, Algorithm Development
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Jun 2019 - Jun 2021
Analysis pipeline for WSIM-MS2 data to recovering DNA adducts relevant to cancer initiation.
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Consultant, Mass Spec Lab Deployment
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Jun 2019 - Dec 2020
Lab construction and high performance infrastructure
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Washington University in St. Louis
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United States
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Higher Education
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700 & Above Employee
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Ph.D. Candidate
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Jul 2011 - Jan 2017
Patti Lab, Department of Chemistry and GeneticsSystems-Level Annotation of a Metabolomics Data Set Reduces 25,000 Features to Fewer than 1000 Metabolites (Mahieu, 2017)
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Credentialing Kit for Metabolomics- Product Pioneering, Development, and Launch
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Jul 2011 - Jan 2017
Developed the "Credentialed E. coli Cell Extract Kit." Engaged commercial partner Cambride Isotope Labs to commercialize and market the kit through publications and lectures.
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University of Missouri-Columbia
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United States
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Higher Education
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700 & Above Employee
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Research Assistant
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May 2010 - May 2011
Undergraduate thesis: study of hypoxia-activated chemotherapeutics, synthesis of a fluorescent chemical probe of cellular hypoxia.
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Tutor, Total Person Program
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Jun 2009 - May 2010
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Teva Pharmaceuticals
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Israel
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Pharmaceutical Manufacturing
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700 & Above Employee
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Quality Control Analyst
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May 2008 - Aug 2010
GMP/ISO 9001 conformity, FDA compliant analytical testing and quality control for antibiotic APIs. GMP/ISO 9001 conformity, FDA compliant analytical testing and quality control for antibiotic APIs.
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Photography and Web Development
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2005 - 2010
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Education
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Washington University in St. Louis
PhD, Chemistry -
University of Missouri-Columbia
BS Chemistry and BS with Honors Biochemistry