Pharmaceuticals & Materials Specialist

• Apr 2022 - Present

R&D Project Manager - Polymer and Material Technologies For Medical Devices

• May 2020 - Mar 2022

I lead cross-functional projects related to assessment and development of advanced polymer-based materials which meet the standards of safety and performance of medical devices.• Coordinated the feasibility and validation tests, resulting in technical reports on the selected raw material.• Generated project documentation according to design control process.• Created an internal comparative polymer database to optimize the choice of polymers.• Collaborated closely with 5 BUs, 11 manufacturing sites, suppliers, and purchase, quality and regulatory affairs departements.• Collected, provided comprehensive analysis of fundamental data through bibliographic research, and preparated technical reports that became the basis for:-extension of the shelf-life of an oncology device during storage which leads to gain productivity (implemented).-understanding the challenges and opportunities of new generation of biomaterials in medical devices (pending).-studying the effectiveness of plastics blends to gain insight into their compatibility, morphologies, and mechanical properties (implemented).• Cooperated closely with French public research laboratories related to the development of antimicrobial materials for medical devices, and optimization of the arterial pressure signal.• Supervised an engineering student.

R&D Project Leader - Specific Anti-Biofilm Wound Dressing | Controlled Release System

• Oct 2016 - Dec 2019

As a principal investigator, I realized the project entitled "Development of a wound dressing as a specific anti-biofilm protein release system. Towards chronic wound healing" in Polymers, Biopolymers, Surfaces laboratory, UMR CNRS 6270. Funded by GRR CRUNCh SESA Normandy Region and the European Regional Development Fund.Produced 2 scientific publications, 6 oral presentations and 3 posters at national and international conferences.• Managed an R&D project.• Designed a wound dressing from biodegradable polymers with an interconnected porous network that promotes the healing of a chronic wound.• Managed the physico-chemical performances (mechanical, gas permeability) required for wound dressing.• Studied the loading and the release profile of actives substances (proteins and antibiotic-loaded nanoparticles).• Evaluated the biological activity using an in vitro bacterial biofilm model.• Conducted the cytocompatibility tests using 2-D and 3-D reconstructed human epidermis models.• Collaborated closely with both internal (3 teams) and external (LMSM Laboratory, Evreux) units.• Supervised undergraduate student.• Taught practical work for undergraduate chemist and biologist students (72 hours).• Participated in public science event (Festival de l'Excellence Normande). Courses: • Innovation and project management (55 hours).• Training including bacterial biofilms, antibiotic resistance, and surface functionalization (70 hours).

Research Investigator - Improving The Bioavailability by Engineered Nanoparticles

• Jan 2016 - Jun 2016

I realized the research project entitled " Development of lipid based nanocarriers for oral delivery of decitabine to acute myeloid leukemia treatments " in the Micro and Nanomedicine Biomimetic Unity - UMR INSERM 1066 CNRS 6021.Produced 1 scientific publication.• Managed a research project.• Carried out a chemical modification of an anticancer agent (hydrophilic) to improve oral bioavailibility.• Characterized the materials synthesized with various techniques including NMR and LC-MS-MS spectrometry.• Conducted the formulation and the physicochemical characterization of modified agent-loaded lipid nanoparticles.• Handled the stability assays of modified agent-loaded lipid nanoparticles.

Research Investigator - Improving The Bioavailability by Engineered Nanoparticles

• Apr 2015 - May 2015

I realized the project entitled "Formulation of solid lipid nanoparticles of a glucocorticoid agent for the treatment of rheumatoid arthritis" in the Galien Paris Sud Institute - UMR CNRS 8612.• Conducted the formulation of nanoparticles based on glucocorticoid prodrug and study the effect of lyophilization with or without cryoprotectants on the physicochemical stability of nanoparticles.• Validated the mouse organ grinding method.• Improved the % release of drugs in phosphate-buffered saline.

Hospital and Clinical Pharmacist Assistant

• Sep 2013 - May 2014

I experienced the role of the clinical pharmacist through participation in mini-rotations throughout multiple specialty areas (cardiology, pediatrics, oncology, infectiology), and of hospital pharmacist.• Provided pharmaceutical care to the patients: monitored and reported drug safety and interactions.• Collaborated closely with healthcare professionals to ensure delivering optimal medication therapy to patients.• Assisted in dispensing of medications, formulating and re-formulating dosage forms.• Developed my interpersonal communication skills with patients and healthcare team.

Analytical Development Associate - Pharmaceutical Industry

• Aug 2013 - Aug 2013

Pharmaline’s manufacturing site (formulation development and production of generic medicines). This work was performed in the analytical development and quality control department.• Conducted analytical and physico-chemical assays on solid dosage forms under Good Manufacturing Practice (GMP) and according to valid ICH guidelines. Pharmaline’s manufacturing site (formulation development and production of generic medicines). This work was performed in the analytical development and quality control department.• Conducted analytical and physico-chemical assays on solid dosage forms under Good Manufacturing Practice (GMP) and according to valid ICH guidelines.

Research Assistant - Clinical and Experimental Toxicology

• Jun 2013 - Jul 2013

Laboratory of toxicology, Faculty of Pharmacy.• Handled good cell culture practices, molecular biology techniques (PCR, RT-PCR), and analytical technique (GC-MS) for the activation of dendritic cells by metallic haptens. Laboratory of toxicology, Faculty of Pharmacy.• Handled good cell culture practices, molecular biology techniques (PCR, RT-PCR), and analytical technique (GC-MS) for the activation of dendritic cells by metallic haptens.