Minghui Ao
Data Analyst III at Frederick National Laboratory for Cancer Research- Claim this Profile
Click to upgrade to our gold package
for the full feature experience.
Topline Score
Bio
Experience
-
Frederick National Laboratory for Cancer Research
-
United States
-
Biotechnology Research
-
400 - 500 Employee
-
Data Analyst III
-
Mar 2022 - Present
Data analysis for proteomics cancer research. Develop software. Data analysis for proteomics cancer research. Develop software.
-
-
-
The Johns Hopkins University School of Medicine
-
United States
-
Hospitals and Health Care
-
700 & Above Employee
-
Research Specialist II
-
Dec 2017 - May 2020
1. Bioinformatics, Data Analysis and Visualization: • Analyzed proteomic and glyco-proteomic data using statistical and machine learning methods, including hypothesis testing, normalization, classification, clustering, and regression for cancer and HIV research. 2. Software Development for data analysis: • Develop software in Python to process mass spectrometry O-linked data, including signal processing, noise reduction, feature detection, and pattern recognition. This software is packed and published on Github (https://github.com/appleTree2017/Extraction-of-O-linked-glycopeptides-EXoO-). • Developed GPQuest, a search engine in Python for intact glycopeptide identification in tandem mass spectrometry (Website: https://www.biomarkercenter.org/gpquest). • Developed modules for data analysis and visualizations, including normalization, PCA, differentiation analysis, Hieratical clustering, Volcano plots. These modules were integrated into a data analysis pipeline named Omics One. 3. Website/Database Development: • Developed N-GlycositeAtlas: an online database resource for mass spectrometry-based human N-linked glycoprotein and glycosylation site mapping (Django App deployed on AWS). Website: https://www.biomarkercenter.org/nglycositeatlas • Developed, designed, and maintained the website for Center for Biomarkers Discovery and Translation, Analytical Chemistry Division, Johns Hopkins University. • Develop lab specimen storage and lab supplies ordering systems. Show less
-
-
-
The Johns Hopkins University School of Medicine
-
United States
-
Hospitals and Health Care
-
700 & Above Employee
-
Research Program Coordinator
-
Mar 2014 - 2015
• Project management for an HIV international clinical research site in China.• Document management and translation.
-
-
Research Technologist
-
Jun 2012 - Mar 2014
• Conducted hands-on experiments on biomarker discovery and validation for cancer research. • Analyzed data for mass spectrometry results.
-
-
-
University of Warwick
-
United Kingdom
-
Higher Education
-
700 & Above Employee
-
Reaearch Technician
-
Nov 2008 - Jul 2011
• Studied echovirus 7 entry mechanism by using inhibitory drugs and short inferring RNA (siRNA) to block specific component of endocytosis pathways. • Conducted experiments and reported results. • Studied echovirus 7 entry mechanism by using inhibitory drugs and short inferring RNA (siRNA) to block specific component of endocytosis pathways. • Conducted experiments and reported results.
-
-
Education
-
The George Washington University
Master’s Degree, Computer Science -
University of Warwick
Master of Science (MSc), Biological Sciences -
Guangxi University
Bachelor of Science (BSc), Biotechnology