Minghui Ao

Data Analyst III at Frederick National Laboratory for Cancer Research
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Contact Information
us****@****om
(386) 825-5501
Location
Baltimore, Maryland, United States, US

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Experience

    • United States
    • Biotechnology Research
    • 400 - 500 Employee
    • Data Analyst III
      • Mar 2022 - Present

      Data analysis for proteomics cancer research. Develop software. Data analysis for proteomics cancer research. Develop software.

    • United States
    • Hospitals and Health Care
    • 700 & Above Employee
    • Research Specialist II
      • Dec 2017 - May 2020

      1. Bioinformatics, Data Analysis and Visualization: • Analyzed proteomic and glyco-proteomic data using statistical and machine learning methods, including hypothesis testing, normalization, classification, clustering, and regression for cancer and HIV research. 2. Software Development for data analysis: • Develop software in Python to process mass spectrometry O-linked data, including signal processing, noise reduction, feature detection, and pattern recognition. This software is packed and published on Github (https://github.com/appleTree2017/Extraction-of-O-linked-glycopeptides-EXoO-). • Developed GPQuest, a search engine in Python for intact glycopeptide identification in tandem mass spectrometry (Website: https://www.biomarkercenter.org/gpquest). • Developed modules for data analysis and visualizations, including normalization, PCA, differentiation analysis, Hieratical clustering, Volcano plots. These modules were integrated into a data analysis pipeline named Omics One. 3. Website/Database Development: • Developed N-GlycositeAtlas: an online database resource for mass spectrometry-based human N-linked glycoprotein and glycosylation site mapping (Django App deployed on AWS). Website: https://www.biomarkercenter.org/nglycositeatlas • Developed, designed, and maintained the website for Center for Biomarkers Discovery and Translation, Analytical Chemistry Division, Johns Hopkins University. • Develop lab specimen storage and lab supplies ordering systems. Show less

    • United States
    • Hospitals and Health Care
    • 700 & Above Employee
    • Research Program Coordinator
      • Mar 2014 - 2015

      • Project management for an HIV international clinical research site in China.• Document management and translation.

    • Research Technologist
      • Jun 2012 - Mar 2014

      • Conducted hands-on experiments on biomarker discovery and validation for cancer research. • Analyzed data for mass spectrometry results.

    • United Kingdom
    • Higher Education
    • 700 & Above Employee
    • Reaearch Technician
      • Nov 2008 - Jul 2011

      • Studied echovirus 7 entry mechanism by using inhibitory drugs and short inferring RNA (siRNA) to block specific component of endocytosis pathways. • Conducted experiments and reported results. • Studied echovirus 7 entry mechanism by using inhibitory drugs and short inferring RNA (siRNA) to block specific component of endocytosis pathways. • Conducted experiments and reported results.

Education

  • The George Washington University
    Master’s Degree, Computer Science
    2016 - 2017
  • University of Warwick
    Master of Science (MSc), Biological Sciences
    2007 - 2009
  • Guangxi University
    Bachelor of Science (BSc), Biotechnology
    2002 - 2006

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