Ming-Jin Jheng
Scientist I at HARBOUR BIOMED- Claim this Profile
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Bio
Credentials
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Veterinarian certificate
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Experience
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Scientist I
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Nov 2018 - Present
As a scientist I in the discovery oncology department, my main responsibility and achievement are as the following:1. Lead antibody drug discovery projects from hit to the candidate. Set go/no-go decision criteria for the projects. Review patent and literature. Follow the competitive landscape of the target. Update the state of art in disease treatment. As a project leader, I successfully lead the project to get a good candidate.2. Collaborate with antibody technology, early… As a scientist I in the discovery oncology department, my main responsibility and achievement are as the following:1. Lead antibody drug discovery projects from hit to the candidate. Set go/no-go decision criteria for the projects. Review patent and literature. Follow the competitive landscape of the target. Update the state of art in disease treatment. As a project leader, I successfully lead the project to get a good candidate.2. Collaborate with antibody technology, early development, CMC, clinical, and business development units.3. Independently set up and validate in vitro cell-based assay. 4. Facilitate technical problem solving, and troubleshooting.5. Support bioanalysis of pharmacokinetics for non-clinical study including assay development and validation.6. Development of junior scientists in BA areas.7. Prepare technical documents, and write patents. Independently present work at a group or project meeting. Deliver updates to senior-level management. Show more Show less
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Associate Researcher
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May 2015 - Nov 2018
As an associate researcher in the pre-clinical drug development department, my responsibility and achievement are as the following: 1. Design and execute mice in-life manipulation for PK studies of new chemical entities (NCEs) and biologics, and prepare study reports. 2. Development of large molecule bioanalytical methods and analysis of PK samples. 3. Support mice acute toxicology studies and prepare study reports. 4. Independently develop and execute the molecular-based assay.… As an associate researcher in the pre-clinical drug development department, my responsibility and achievement are as the following: 1. Design and execute mice in-life manipulation for PK studies of new chemical entities (NCEs) and biologics, and prepare study reports. 2. Development of large molecule bioanalytical methods and analysis of PK samples. 3. Support mice acute toxicology studies and prepare study reports. 4. Independently develop and execute the molecular-based assay. 5. Design and execute cellular assay, and identify metabolite of antibody-drug conjugates (ADCs). 6. Design and perform in vitro plasma stability studies of NCEs and ADCs. 7. Propose new projects. Lead drug discovery projects. Set go/no-go decision criteria for the projects. Review patent and literature. Follow the competitive landscape of the target. Update the state of art in disease treatment. Show more Show less
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Bioengineer
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Sep 2013 - Aug 2014
As an antigen production bioengineer, my main responsibility and achievement are as the following:1. Overexpress and purify about 300 recombinant proteins from E. coli, including soluble protein and inclusion body. 2. Characterize proteins by using gel electrophoresis or Western blotting. 3. Prepare peptide conjugated antigen for immunization.4. Write up experimental procedures and data of daily work.5. Present results in the group and team meetings
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Education
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National Taiwan University
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National Chiayi University