Experience

Medicines Discovery Catapult

• United Kingdom
• Biotechnology
• 100 - 200 Employee

• Quality Management Scientist

  • Jan 2023 - Present



Charles River Laboratories

• United States
• Biotechnology Research
• 700 & Above Employee

• Laboratory Scientist

  • Dec 2018 - Dec 2022

  My role involved the planning, execution and reporting of assays for a variety ex-vivo and in-vitro studies with end-points such as Luminex, ELISA, ELISpot, platelet aggregation, protein analysis and analysis of FITC-dextran in mouse sera. I managed 6 studies spanning 5 different clinical trials with the same client, coordinating both internal logistics and external communication with the client, other agencies involved and clinical sites. I have experience in bioanalytical method… Show more My role involved the planning, execution and reporting of assays for a variety ex-vivo and in-vitro studies with end-points such as Luminex, ELISA, ELISpot, platelet aggregation, protein analysis and analysis of FITC-dextran in mouse sera. I managed 6 studies spanning 5 different clinical trials with the same client, coordinating both internal logistics and external communication with the client, other agencies involved and clinical sites. I have experience in bioanalytical method validation following FDA guidance for immunoassays, I regularly performed PBMC isolation and Luminex analysis on clinical samples and trained new operators in these techniques. I also supported molecular work consisting of RNA extraction, quantification and analysis of gene expression by Nanostring for clinical trials. I frequently liaised with colleagues in Client Services when reviewing feasibility of proposals and costings of lab work prior to client signature. Other skills used include tissue processing (murine spleen, bone marrow, colon, serum, plasma), aseptic technique, cell culture, measurement of cell proliferation using tritiated thymidine and qPCR.

• Laboratory Technician

  • Oct 2017 - Nov 2018

  My role as a Lab Tech involved supporting the routine function of laboratories across the three departments; Tissue Culture, Analytical and Infectious Diseases. This included, but was not limited to: PBMC Isolation, tissue processing, cell counting, maintenance of flow cytometers, mycoplasma testing using PCR, protein assays, assisting with ELISA tests, and homogenisation and dilution of samples for spread plating. I reached a level of competency in various techniques that allows me to… Show more My role as a Lab Tech involved supporting the routine function of laboratories across the three departments; Tissue Culture, Analytical and Infectious Diseases. This included, but was not limited to: PBMC Isolation, tissue processing, cell counting, maintenance of flow cytometers, mycoplasma testing using PCR, protein assays, assisting with ELISA tests, and homogenisation and dilution of samples for spread plating. I reached a level of competency in various techniques that allows me to train other staff members. I also performed administrative tasks such as ordering and receiving consumables. Whilst in this role, I implemented a money-saving initiative that successfully reduced costs and boosted productivity within the Technical Team.



QIAGEN

• Netherlands
• Biotechnology Research
• 700 & Above Employee

• Technical Assistant

  • Mar 2017 - Sep 2017

  My role as a Technical Assistant involved supporting the planning and execution of laboratory work and reporting the results of the experiments as part of a team in Product Development. This included PCR setup (including HRM assays), precision serial dilutions, preparing worksheets and accurately recording of laboratory work within them, working within a team to ensure safety and efficiency in the laboratory and ordering and receiving samples and reagents to maintain stocks. My role as a Technical Assistant involved supporting the planning and execution of laboratory work and reporting the results of the experiments as part of a team in Product Development. This included PCR setup (including HRM assays), precision serial dilutions, preparing worksheets and accurately recording of laboratory work within them, working within a team to ensure safety and efficiency in the laboratory and ordering and receiving samples and reagents to maintain stocks.



Siemens Healthcare Diagnostics

• Llanberis, Gwynedd, North Wales

• Work Experience- Technical Operations

  • Mar 2016 - Mar 2016

  I was awarded a scholarship as part of the MSc which allowed me to attend a placement at the Siemens site in Llanberis which manufactures and distributes IMMULITE reagents. During the placement I was inducted to various departments which gave me experience of quality control processes, practical lab work in an industrial setting, data analysis and interpreting of work cards and experiments for the Technical Operations and Quality Control review departments. I also attended change review board… Show more I was awarded a scholarship as part of the MSc which allowed me to attend a placement at the Siemens site in Llanberis which manufactures and distributes IMMULITE reagents. During the placement I was inducted to various departments which gave me experience of quality control processes, practical lab work in an industrial setting, data analysis and interpreting of work cards and experiments for the Technical Operations and Quality Control review departments. I also attended change review board meetings relating to batch up-scaling processes. Show less I was awarded a scholarship as part of the MSc which allowed me to attend a placement at the Siemens site in Llanberis which manufactures and distributes IMMULITE reagents. During the placement I was inducted to various departments which gave me experience of quality control processes, practical lab work in an industrial setting, data analysis and interpreting of work cards and experiments for the Technical Operations and Quality Control review departments. I also attended change review board… Show more I was awarded a scholarship as part of the MSc which allowed me to attend a placement at the Siemens site in Llanberis which manufactures and distributes IMMULITE reagents. During the placement I was inducted to various departments which gave me experience of quality control processes, practical lab work in an industrial setting, data analysis and interpreting of work cards and experiments for the Technical Operations and Quality Control review departments. I also attended change review board meetings relating to batch up-scaling processes. Show less



Hwyl Hyfryd Play Scheme (Action for Children)

• Maes Hyfryd Specialist High School, Flint

• Playworker (Summer Job)

  • Jul 2015 - Aug 2015

  Employed by Action for Children to provide a summer scheme for the students of the local specialist high schools and give respite to parents. I was responsible for providing care and supervision to students between the ages of 11 to 19 with a range of complex physical and behavioural needs. Worked on the play scheme during the school summer holiday in 2013, 2014 and 2015. Employed by Action for Children to provide a summer scheme for the students of the local specialist high schools and give respite to parents. I was responsible for providing care and supervision to students between the ages of 11 to 19 with a range of complex physical and behavioural needs. Worked on the play scheme during the school summer holiday in 2013, 2014 and 2015.