Experience

Arch Oncology

• United States
• Biotechnology Research
• 1 - 100 Employee

• Senior Scientist

  • Feb 2021 - Oct 2021

  Greater St. Louis

• Research Scientist

  • Jan 2016 - Feb 2021

  Greater St. Louis Area ● Discovered a unique characteristic of a set of our antibodies that significantly differentiates them from others in the field. ● Leading a team to determine the mechanism of action of our antibodies to identify potential combinations, biomarkers, and to stratify patient populations. ● Collaborated with the team recommending the selection of lead antibodies presented to senior leadership. ● Leading a team to collaborate with CROs and academic partners to generate data supporting… Show more ● Discovered a unique characteristic of a set of our antibodies that significantly differentiates them from others in the field. ● Leading a team to determine the mechanism of action of our antibodies to identify potential combinations, biomarkers, and to stratify patient populations. ● Collaborated with the team recommending the selection of lead antibodies presented to senior leadership. ● Leading a team to collaborate with CROs and academic partners to generate data supporting preclinical development of molecules. ● Developing therapeutic monoclonal antibodies to treat cancer and other indications. ● Designing and optimizing cell-based and biochemical assays to characterize therapeutic antibodies. ● Preparing study reports to enable regulatory authority submissions. ● Utilized interpersonal communication skills to effectively communicate among colleagues to ensure efficient quality and timelines are met.



Eurofins

• Luxembourg
• Biotechnology Research
• 700 & Above Employee

• Scientist II

  • Jul 2014 - Dec 2015

  Saint Charles, MO ● Drove new business solutions through leadership and execution of multiple custom flexlab projects that expanded Eurofins' capacity in cell-based assays. ● Lead manager on multiple projects for a key client. Improved efficiency of the Sodium Channel Screening Project by 25% since inception. ● Lead implementation of a new technology, the IonFlux HT, including training of other scientist, development and validation of 13 cell lines in 35 new assays, presentation of data at a scientific… Show more ● Drove new business solutions through leadership and execution of multiple custom flexlab projects that expanded Eurofins' capacity in cell-based assays. ● Lead manager on multiple projects for a key client. Improved efficiency of the Sodium Channel Screening Project by 25% since inception. ● Lead implementation of a new technology, the IonFlux HT, including training of other scientist, development and validation of 13 cell lines in 35 new assays, presentation of data at a scientific meeting and in webinars which resulted in generation of greater than $250K in new client business. ● Top performer in providing standard service projects and development projects. Provided high quality customer-oriented service that positively impacted business. ● Saved the company $35K by changing the format of a routinely run assay. ● Streamlined data analysis using XLfit for a large screening project resulting in a significant reduction in time to deliver data to the client. ● Recruited, trained and mentored a new scientist. ● Improved the work environment and provide efficient quality work to customers using interpersonal communication problem solving skills. ● Utilized problem solving skills to address any issues that arose during assay development and after assays had been launched for screening and during cell line generation. ● Supported sales/marketing launches of new cell lines/services by developing protocols and validation documents.

• Scientist I

  • Mar 2012 - Jul 2014

  Saint Charles, MO ● Performance in top 5% of the company and received a promotion to Research Scientist II. ● Acted as a role model for the team in objectively identifying high risk processes and cell lines followed by experimental design to facilitate repair. ● Provided mentorship and leadership to other team members to strengthen the performance of the Ion Channel Team. ● Led by example in providing a gold standard of how staff should build customer satisfaction and delivered every project with… Show more ● Performance in top 5% of the company and received a promotion to Research Scientist II. ● Acted as a role model for the team in objectively identifying high risk processes and cell lines followed by experimental design to facilitate repair. ● Provided mentorship and leadership to other team members to strengthen the performance of the Ion Channel Team. ● Led by example in providing a gold standard of how staff should build customer satisfaction and delivered every project with competence and integrity, gaining rapport with customers. ● Generated data for customer screening assays using several methods including automated electrophysiology, FLIPR, flow cytometry and wrote corresponding data reports. ● Designed, optimized, and validated customized assays based on awareness of customer requirements.



Merck

• United States
• Pharmaceutical Manufacturing
• 700 & Above Employee

• Assistant Scientist

  • Nov 2009 - Dec 2011

  Kenilworth, NJ ● Developed and optimized a new multi-parametric, high-content imaging-based toxicity assay for use in the HCV program. Collaborated with colleagues to fully automate the assay with the latest robotic technology. Presented the data in a poster and in a talk given to the department. ● Designed a high-content imaging-based phospho-protein target engagement assay to study the MOA of an oncology target. ● Developed a high-content imaging-based receptor internalization assay for use in an… Show more ● Developed and optimized a new multi-parametric, high-content imaging-based toxicity assay for use in the HCV program. Collaborated with colleagues to fully automate the assay with the latest robotic technology. Presented the data in a poster and in a talk given to the department. ● Designed a high-content imaging-based phospho-protein target engagement assay to study the MOA of an oncology target. ● Developed a high-content imaging-based receptor internalization assay for use in an Alzheimer’s program. Show less



Schering-Plough Research Institute

• United States
• Pharmaceutical Manufacturing
• 400 - 500 Employee

• Assistant Scientist

  • Jan 2007 - Nov 2009

  Kenilworth, NJ ● Designed, optimized and ran cell-based assays. ● Discovered an issue with the screening assay used for SAR and hit identification for the Nav1.7 inhibitor program. Optimized the assay resulting in more accurate correlation with manual patch clamp data and hit identification for potency and selectivity. ● Optimized a new non-radioactive hERG binding assay and presented the data in a poster. ● Generated and validated two (2) ion-channel cell lines.



St. Michael's Medical Center

• Molecular Virologist

  • Nov 2003 - Dec 2006

  Newark, NJ ● Designed a virus that targeted HIV infected cells and evaluated its use as a delivery system for new treatments, including RNAi. ● Developed and executed a study utilizing a dendritic cell-based vaccine in the rhesus macaque SIV model. Co-first authored a paper in a peer-reviewed journal that detailed the data and findings of the study. ● Developed an assay to detect GB virus C in HIV infected patients to evaluate the correlation of co-infection with disease progress. Published a… Show more ● Designed a virus that targeted HIV infected cells and evaluated its use as a delivery system for new treatments, including RNAi. ● Developed and executed a study utilizing a dendritic cell-based vaccine in the rhesus macaque SIV model. Co-first authored a paper in a peer-reviewed journal that detailed the data and findings of the study. ● Developed an assay to detect GB virus C in HIV infected patients to evaluate the correlation of co-infection with disease progress. Published a paper in a peer-reviewed journal that detailed the results. ● Managed daily lab operations, design experiments, write protocols, data analysis, interview and train new lab personnel. Show less



Roche

• Switzerland
• Biotechnology Research
• 700 & Above Employee

• Quality Control Scientist

  • Sep 2002 - Mar 2003

  Bridgewater, NJ ● Performed release and stability testing for ELISA format, PCR-based Infectious Disease detection kits according to approved SOPs. ● Responsible for accuracy, quality, and timeliness of testing results, authoring SOPs and validating data.