Experience

Singular Genomics

• United States
• Biotechnology Research
• 100 - 200 Employee

• Senior Research Engineer - System Integration

  • Mar 2022 - Present

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• Research Engineer II - System Integration

  • Apr 2021 - Mar 2022

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GeneFluidics

• United States
• Biotechnology
• 1 - 100 Employee

• Principal Scientist

  • Jan 2018 - Apr 2021

  - Designed and developed a rapid, novel diagnostic assay for the detection and identification of pathogenic bacteria from whole blood samples. Developed assay was capable of detecting bacteria samples at a concentration of 1 CFU/mL, an improvement over previous limit of detection of 1E8 CFU/mL. - Developed an algorithm for classification of susceptibility profile of clinical isolates based on electrochemical signals from assay and incorporated this algorithm into automated assay system… Show more - Designed and developed a rapid, novel diagnostic assay for the detection and identification of pathogenic bacteria from whole blood samples. Developed assay was capable of detecting bacteria samples at a concentration of 1 CFU/mL, an improvement over previous limit of detection of 1E8 CFU/mL. - Developed an algorithm for classification of susceptibility profile of clinical isolates based on electrochemical signals from assay and incorporated this algorithm into automated assay system. Algorithm accepts raw data from biosensor assay as input, cleans data, removes outliers, and compares results to empirically derived cutoffs to determine whether a given clinical isolate or sample is resistant or susceptible to each drug in a panel of antibiotics. Testing of challenge isolates with MIC values near breakpoints of each drug with this algorithm yielded 100% categorical agreement. -Contributed to design and assembly of three automated assay systems for different clinical sample types. Programmed Arduino scripts to tailor system processes to specific assay requirements.

• Research Scientist

  • Jan 2016 - Jan 2018

  - Optimized assay for pathogen identification and AST in clinical urine samples. This assay was used to test clinical samples and achieved 99% sensitivity and 100% specificity for detection of a panel of Gram-negative bacilli. - Coordinated written responses and meetings with FDA regarding three products in development. Gave presentation to team of FDA reviewers to discuss technical details and reach agreements regarding acceptable clinical testing parameters. All products in development are… Show more - Optimized assay for pathogen identification and AST in clinical urine samples. This assay was used to test clinical samples and achieved 99% sensitivity and 100% specificity for detection of a panel of Gram-negative bacilli. - Coordinated written responses and meetings with FDA regarding three products in development. Gave presentation to team of FDA reviewers to discuss technical details and reach agreements regarding acceptable clinical testing parameters. All products in development are De Novo diagnostic devices with no existing predicates; an extensive submission and feedback process was necessary to convey how our devices combined novel technology with CLSI guidelines to achieve results within hours.

• Intern

  • Oct 2015 - Jan 2016

  - Assembled and tested a microfluidic cartridge device for the identification of bacterial pathogens and subsequent AST with an automated robotic assay system. - Routinely performed root cause analysis on failed diagnostic experiments and malfunctioning production equipment. Documented all work and records in accordance with GLP and ISO regulations. Random assay failures reduced from 10% to less than 1%. - Assisted in writing applications for NIH grants for small businesses.



UCLA Mathematics

• United States
• Higher Education
• 1 - 100 Employee

• Undergraduate Researcher

  • Jul 2014 - Jun 2015

  Visualized laminar flows of air with laser imaging to observe the emission pattern of fungal spores Visualized laminar flows of air with laser imaging to observe the emission pattern of fungal spores