Experience

Abilita Bio, Inc.

• United States
• Biotechnology Research

• CSO

  • Jul 2022 - Present

  San Diego, California, United States Leveraging Abilita's innovative membrane protein platform to discover groundbreaking therapeutics.



The Frost Institute for Chemistry and Molecular Sciences at University of Miami

• Director of Technology Development

  • Sep 2022 - Present

  Miami, Florida, United States Leveraging state-of-the-art cryo-electron microscopy to fuel structure-based discovery for challenging membrane protein targets.



SB SciTech

• Owner

  • Dec 2021 - Present

  United States Independent research consulting services in drug discovery focusing on structure-based design and GPCR pharmacology. I have expertise in applying cryo-electron microscopy, x-ray crystallography, computational chemistry, and data science to drug discovery. My past work has led to a dramatic increase in available GPCR membrane protein structures and the successful discovery of novel marketed and clinical-stage drugs. Specific roles and activities: • Deploying novel methods for… Show more Independent research consulting services in drug discovery focusing on structure-based design and GPCR pharmacology. I have expertise in applying cryo-electron microscopy, x-ray crystallography, computational chemistry, and data science to drug discovery. My past work has led to a dramatic increase in available GPCR membrane protein structures and the successful discovery of novel marketed and clinical-stage drugs. Specific roles and activities: • Deploying novel methods for expression, purification, crystallization and preparation of homogenous samples for cryo-EM single-particle reconstruction • Data collection and processing strategies for x-ray crystallography and cryo-EM campaigns • Model building and optimization strategies for maximizing impact on ligand design • Hit identification strategies utilizing structure and ligand-based approaches • Strategic leveraging of structural data for hit-to-lead and lead-optimization phases of drug discovery • Data management approaches to facilitate streamlined capture of mission-critical information • Interpretation of in-vitro pharmacology data in the context of structure and ligand-based SAR • Utilizing public and internal data sources to provide unique interpretations Show less



Structure Therapeutics

• United States
• Biotechnology Research
• 1 - 100 Employee

• Co-Founder / Chief Technology Officer

  • Nov 2016 - Nov 2021

  San Diego, California, United States


GPCR Consortium
• President

  • Sep 2014 - May 2019

Receptos
• India
• Director

  • Feb 2012 - Aug 2014


Receptos, Inc

• United States

• Associate Director Structural Biology

  • Mar 2009 - Feb 2012

  I am leading a team in the generation and integration of structural information pertaining to GPCRs with various ligands and co-factors bound. This information is used for the discovery and optimization of the next generation of pharmaceutically active compounds. Significantly enhancing the development process.



The Scripps Research Institute

• Scientific Associate

  • Feb 2004 - Mar 2009

  Developing methodology for membrane protein structural biology and structure based drug design.



Sagres Pharmaceuticals

• Scientist

  • Jan 2003 - Feb 2004

  Development of platform technology for membrane protein structure based drug design efforts.