Michael Finucane
Scientist at Crosshair Therapeutics- Claim this Profile
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Experience
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Crosshair Therapeutics
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United States
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Biotechnology Research
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1 - 100 Employee
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Scientist
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Jul 2022 - Present
Sunnyvale, California, United States Currently using gene assembly to develop a very large expression system. This will later be used to develop a novel drug platform.
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STATEGICS, INC.
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United States
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Scientist
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Jun 2019 - Jul 2022
Santa Clara County, California, United States
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Senior Editor
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Mar 2006 - Mar 2019
Taking research papers and grant applications by foreign researchers and polishing them for publication in high-quality journals. Includes editing and content analysis/correction.
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Stanford University
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United States
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Higher Education
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700 & Above Employee
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Research Fellow
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1999 - 2003
Continued work on trp-Repressor under Prof. Oleg Jardetzky, using Molecular Biology to provide useful mutants and Biacore to analyze their interaction with several operator DNA sequences.
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University of Sussex
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United Kingdom
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Higher Education
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700 & Above Employee
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Research Assistant
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1995 - 1999
Developed Phage Display system for stabilizing proteins • Core-directed protein design I: An experimental method for selecting stable proteins from combinatorial libraries. Finucane, M. D., Tuna M, Lees, J. & Woolfson, D. N. Biochemistry 38 11604-11612 1999 • Core-directed protein design II: Rescue of a multiply mutated and destabilised variant of Ubiquitin. Finucane, M. D. & Woolfson, D. N. Biochemistry 38 11613-11623 1999 • Dynamics, Structure and Function of Biological… Show more Developed Phage Display system for stabilizing proteins • Core-directed protein design I: An experimental method for selecting stable proteins from combinatorial libraries. Finucane, M. D., Tuna M, Lees, J. & Woolfson, D. N. Biochemistry 38 11604-11612 1999 • Core-directed protein design II: Rescue of a multiply mutated and destabilised variant of Ubiquitin. Finucane, M. D. & Woolfson, D. N. Biochemistry 38 11613-11623 1999 • Dynamics, Structure and Function of Biological Macromolecules. O. Jardetzky and M. D. Finucane (Eds.) ISBN: 1 58603 032 9 IOSpress 2001 • Protease-based selection of stably folded proteins and protein domains from phage display libraries. Tuna, M., Finucane, M.D., Vlachakis, N. G. M. & Woolfson, D. N. in Phage Display (Practical Approach series, Ed. T. Clackson & H. B. Lowman), Oxford University Press 135-154 2004 Show less
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Stanford
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Real Estate
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Postdoctoral Fellow
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1992 - 1995
Understanding the dynamics of top-repressor using relaxation studies and hydrogen-deuterium exchange
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University College Dublin
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Ireland
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Higher Education
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700 & Above Employee
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Graduate Student
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1987 - 1992
Understanding the mechanism of action of serine proteases by examining transition-state mimics using C13 NMR
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Education
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University College Dublin
Ph.D., Biochemistry, Chemistry minor