Michael Finucane

Scientist at Crosshair Therapeutics
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Location
San Jose, California, United States, US

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Experience

    • United States
    • Biotechnology Research
    • 1 - 100 Employee
    • Scientist
      • Jul 2022 - Present

      Sunnyvale, California, United States Currently using gene assembly to develop a very large expression system. This will later be used to develop a novel drug platform.

    • United States
    • Scientist
      • Jun 2019 - Jul 2022

      Santa Clara County, California, United States

    • Senior Editor
      • Mar 2006 - Mar 2019

      Taking research papers and grant applications by foreign researchers and polishing them for publication in high-quality journals. Includes editing and content analysis/correction.

    • United States
    • Higher Education
    • 700 & Above Employee
    • Research Fellow
      • 1999 - 2003

      Continued work on trp-Repressor under Prof. Oleg Jardetzky, using Molecular Biology to provide useful mutants and Biacore to analyze their interaction with several operator DNA sequences.

    • United Kingdom
    • Higher Education
    • 700 & Above Employee
    • Research Assistant
      • 1995 - 1999

      Developed Phage Display system for stabilizing proteins • Core-directed protein design I: An experimental method for selecting stable proteins from combinatorial libraries. Finucane, M. D., Tuna M, Lees, J. & Woolfson, D. N. Biochemistry 38 11604-11612 1999 • Core-directed protein design II: Rescue of a multiply mutated and destabilised variant of Ubiquitin. Finucane, M. D. & Woolfson, D. N. Biochemistry 38 11613-11623 1999 • Dynamics, Structure and Function of Biological… Show more Developed Phage Display system for stabilizing proteins • Core-directed protein design I: An experimental method for selecting stable proteins from combinatorial libraries. Finucane, M. D., Tuna M, Lees, J. & Woolfson, D. N. Biochemistry 38 11604-11612 1999 • Core-directed protein design II: Rescue of a multiply mutated and destabilised variant of Ubiquitin. Finucane, M. D. & Woolfson, D. N. Biochemistry 38 11613-11623 1999 • Dynamics, Structure and Function of Biological Macromolecules. O. Jardetzky and M. D. Finucane (Eds.) ISBN: 1 58603 032 9 IOSpress 2001 • Protease-based selection of stably folded proteins and protein domains from phage display libraries. Tuna, M., Finucane, M.D., Vlachakis, N. G. M. & Woolfson, D. N. in Phage Display (Practical Approach series, Ed. T. Clackson & H. B. Lowman), Oxford University Press 135-154 2004 Show less

    • Real Estate
    • Postdoctoral Fellow
      • 1992 - 1995

      Understanding the dynamics of top-repressor using relaxation studies and hydrogen-deuterium exchange

    • Ireland
    • Higher Education
    • 700 & Above Employee
    • Graduate Student
      • 1987 - 1992

      Understanding the mechanism of action of serine proteases by examining transition-state mimics using C13 NMR

Education

  • University College Dublin
    Ph.D., Biochemistry, Chemistry minor
    1983 - 1992

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