Mette Kallestrup Spring

Projektkonsulent at SEGES
  • Claim this Profile
Contact Information
us****@****om
(386) 825-5501
Location
Aarhus, Middle Jutland, Denmark, DK

Topline Score

Topline score feature will be out soon.

Bio

Generated by
Topline AI

You need to have a working account to view this content.
You need to have a working account to view this content.

Experience

    • Denmark
    • Farming
    • 300 - 400 Employee
    • Projektkonsulent
      • Aug 2021 - Present

    • Postdoc
      • Sep 2019 - Mar 2020

      Postdoc in ‘CEMBID’ Postdoc in ‘CEMBID’

    • Denmark
    • Hospitals and Health Care
    • 700 & Above Employee
    • Post.doc. at the Department of Clinical Biochemistry
      • Feb 2017 - Sep 2019

      I am currently involved in a project callede DETECT. Here, we have invented an inexpensive in vitro diagnostic Point-Of-Care (POC) device to be used for the quantitative measurement of NOACs (new oral anticoagulant) in whole blood. To day the sample-to-answer time is more than 1 h which postpone surgery and is costly. DETECT is funded by the Danish Agency for Science, Technology and Innovation and is a collaboration between university, hospital and private companies. I am currently involved in a project callede DETECT. Here, we have invented an inexpensive in vitro diagnostic Point-Of-Care (POC) device to be used for the quantitative measurement of NOACs (new oral anticoagulant) in whole blood. To day the sample-to-answer time is more than 1 h which postpone surgery and is costly. DETECT is funded by the Danish Agency for Science, Technology and Innovation and is a collaboration between university, hospital and private companies.

    • Postdoc.
      • Jun 2011 - Jan 2017

      I started in a new research area at the time I began my postdoc. at the Artherosclerosis Research Unit. Here I investigate if diabetes-associated changes in the vascular wall increase susceptibility to atherosclerosis by using mice models of type-1 diabetes and atherosclerosis, molecular techniques, immunofluorescence microscopy and other techniques. At the same time I am supervising students, teaching at university level and reviewer for a number of scientific journals. I started in a new research area at the time I began my postdoc. at the Artherosclerosis Research Unit. Here I investigate if diabetes-associated changes in the vascular wall increase susceptibility to atherosclerosis by using mice models of type-1 diabetes and atherosclerosis, molecular techniques, immunofluorescence microscopy and other techniques. At the same time I am supervising students, teaching at university level and reviewer for a number of scientific journals.

    • PhD
      • Jul 2007 - Mar 2011

      The main purpose of my PhD was to investigate whether endothelial progenitor cells (EPCs) replace dysfunctional endothelial cells and regenerate damaged or denuded endothelium in arterial diseases. This was investigated by use of cell tracking in transgenic mice (transplanted with bone marrow, arterial segments, and/or atherosclerotic plaques), immunofluorescence microscopy and other techniques. We identified limitations and pitfalls in the EPC literature and showed that circulating EPCs do not contribute to endothelial cells in atherosclerosis, allograft vasculopathy, or endothelial regeneration after mechanical vascular injury. Instead, endothelial cell turnover and regeneration is mediated by proliferation and migration of endothelial cells present locally in the arterial wall which probably reflects the common situation in most arterial diseases.

Education

  • Aarhus Universitet
    Doctor of Philosophy - PhD, Medicin
    2007 - 2011
  • Aarhus Universitet
    Cand.scient., Biologi generelt
    2005 - 2006
  • Aarhus Universitet
    Bachelor of Science (BS), Biology
    2000 - 2006
  • Aarhus Katedralskole
    Mathematics graduate student
    1995 - 1998
  • Aarhus Universitet
    Bachelorgrad, Biologi
    -
  • Aarhus Universitet
    Doctor of Philosophy - PhD, Medicin
    -

Community

You need to have a working account to view this content. Click here to join now