Experience

Epic Bio

• United States
• Biotechnology Research
• 1 - 100 Employee

• Senior Scientist

  • Jul 2023 - Present

• Scientist II

  • Jul 2022 - Jul 2023



Invitae

• United States
• Biotechnology Research
• 700 & Above Employee

• Functional Modeling Research Scientist

  • Feb 2020 - Jun 2022



Ingensity IP

• United States
• Law Practice
• 1 - 100 Employee

• Scientific Analyst

  • Jul 2019 - Feb 2020



University of California, San Francisco

• United States
• Higher Education
• 700 & Above Employee

• PhD candidate

  • Sep 2013 - Feb 2020

  Laboratory of Dr. Carol Gross in the Department of Microbiology & Immunology. Systematically interrogating essential gene function in a model Gram-negative bacterium using CRISPR interference (CRISPRi) and high-throughput chemical phenotyping. Developing and evaluating CRISPRi tools for diverse bacteria, and applying those tools to identify novel phage-encoded Cas9 inhibitors. Activities: TEDMED Research Scholar (2018), UCSF Catalyst Intern (2017-18), Teaching Assistant (2014… Show more Laboratory of Dr. Carol Gross in the Department of Microbiology & Immunology. Systematically interrogating essential gene function in a model Gram-negative bacterium using CRISPR interference (CRISPRi) and high-throughput chemical phenotyping. Developing and evaluating CRISPRi tools for diverse bacteria, and applying those tools to identify novel phage-encoded Cas9 inhibitors. Activities: TEDMED Research Scholar (2018), UCSF Catalyst Intern (2017-18), Teaching Assistant (2014, 2017)

• Technology Analyst Intern

  • Jan 2019 - Jul 2019

  Office of Technology Management Evaluating the commercial potential and patentability of inventions at UCSF; meeting with inventors to discuss intellectual property and licensing strategies; drafting marketing disclosure documents.



Massive Science Inc.

• Contributing Writer

  • Sep 2017 - Jan 2019

  Covering recent discoveries in bacterial physiology, genetics, and host-commensal interactions for the general public. https://massivesci.com/people/melanie-silvis/ Covering recent discoveries in bacterial physiology, genetics, and host-commensal interactions for the general public. https://massivesci.com/people/melanie-silvis/



KwaZulu-Natal Research Institute for TB and HIV (K-RITH)

• Durban Area, South Africa

• Visiting Researcher

  • Jun 2013 - Aug 2013

  Laboratory of Dr. Alexander Pym. Developing a single-cell assay for Mycobacterium tuberculosis survival inside macrophages using flow cytometry to accelerate identification of antibiotics relevant in vivo. Laboratory of Dr. Alexander Pym. Developing a single-cell assay for Mycobacterium tuberculosis survival inside macrophages using flow cytometry to accelerate identification of antibiotics relevant in vivo.



Broad Institute of MIT and Harvard

• Research Services
• 700 & Above Employee

• Research Associate I

  • Jul 2011 - Jun 2013

  Laboratory of Dr. Deborah Hung Using high-throughput chemical-genetic approaches for drug-target discovery of novel antibiotics in Mycobacterium tuberculosis; genetic follow-up for antibiotics with specific action during non-replicative persistence (in vitro) and/or during macrophage infection. Laboratory of Dr. Deborah Hung Using high-throughput chemical-genetic approaches for drug-target discovery of novel antibiotics in Mycobacterium tuberculosis; genetic follow-up for antibiotics with specific action during non-replicative persistence (in vitro) and/or during macrophage infection.



CUNY School of Medicine

• United States
• Higher Education
• 400 - 500 Employee

• NYU Summer Undergraduate Research Program Participant

  • Jun 2010 - Aug 2010

  Laboratory of Dr. Jennifer Philips Investigating the protein-protein interactions of Mycobacterium tuberculosis effectors with macrophage autophagy adapter proteins and their roles in host-pathogen dynamics. Laboratory of Dr. Jennifer Philips Investigating the protein-protein interactions of Mycobacterium tuberculosis effectors with macrophage autophagy adapter proteins and their roles in host-pathogen dynamics.



Massachusetts General Hospital

• United States
• Hospitals and Health Care
• 700 & Above Employee

• Research Assistant

  • Jun 2009 - Aug 2009

  Laboratory of Dr. Vanessa Wheeler Investigating tissue-dependent variability in somatic CAG repeat expansion in a mouse model of Huntington's Disease. Laboratory of Dr. Vanessa Wheeler Investigating tissue-dependent variability in somatic CAG repeat expansion in a mouse model of Huntington's Disease.



Chimney Corners Camp YMCA

• Becket, MA

• Counselor

  • Jun 2006 - Aug 2009