Meghan Eberhardt

Associate Director, Analytical Development at Artiva Biotherapeutics
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Contact Information
us****@****om
(386) 825-5501
Location
San Diego, California, United States, US

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Experience

    • United States
    • Biotechnology Research
    • 1 - 100 Employee
    • Associate Director, Analytical Development
      • Aug 2022 - Present

    • United States
    • Biotechnology Research
    • 200 - 300 Employee
    • Senior Scientist
      • Dec 2019 - Aug 2022

    • United States
    • Biotechnology Research
    • 1 - 100 Employee
    • Scientist
      • May 2016 - Jun 2019

      -Project team lead responsible for coordinating and directing interdisciplinary efforts to evaluate novel antibody immunotherapy -Identified and evaluated novel immunology/oncology targets -Developed and executed molecular and cellular functional and signaling assays to evaluate novel targets and therapies -Developed work plans and directly managed CRO for non-human primate toxicology studies to meet aggressive project team timelines. -Authored experiment reports for… Show more -Project team lead responsible for coordinating and directing interdisciplinary efforts to evaluate novel antibody immunotherapy -Identified and evaluated novel immunology/oncology targets -Developed and executed molecular and cellular functional and signaling assays to evaluate novel targets and therapies -Developed work plans and directly managed CRO for non-human primate toxicology studies to meet aggressive project team timelines. -Authored experiment reports for FDA-approved IND and was a major contributing author of pre-IND briefing documents -Participated in teaching seminars intended to increase knowledge and communication between interdisciplinary coworkers Show less -Project team lead responsible for coordinating and directing interdisciplinary efforts to evaluate novel antibody immunotherapy -Identified and evaluated novel immunology/oncology targets -Developed and executed molecular and cellular functional and signaling assays to evaluate novel targets and therapies -Developed work plans and directly managed CRO for non-human primate toxicology studies to meet aggressive project team timelines. -Authored experiment reports for… Show more -Project team lead responsible for coordinating and directing interdisciplinary efforts to evaluate novel antibody immunotherapy -Identified and evaluated novel immunology/oncology targets -Developed and executed molecular and cellular functional and signaling assays to evaluate novel targets and therapies -Developed work plans and directly managed CRO for non-human primate toxicology studies to meet aggressive project team timelines. -Authored experiment reports for FDA-approved IND and was a major contributing author of pre-IND briefing documents -Participated in teaching seminars intended to increase knowledge and communication between interdisciplinary coworkers Show less

    • United States
    • Higher Education
    • 700 & Above Employee
    • Postdoctoral Researcher
      • Jun 2013 - May 2016

      • Coordinate and implement a single protein vaccine study in cytomegalovirus infected rhesus macaques aimed at altering already established host-viral pattern of persistent infection • Evaluate cellular immune responses by flow cytometry and immunohistochemistry • Correlate specific IL-10 cytokine responses and chronic cytomegalovirus shedding in oral mucosa • Evaluate and test antibody cross-reactivity of anti-viral IL-10 antibodies to cellular IL-10 using ELISA, Western Blot… Show more • Coordinate and implement a single protein vaccine study in cytomegalovirus infected rhesus macaques aimed at altering already established host-viral pattern of persistent infection • Evaluate cellular immune responses by flow cytometry and immunohistochemistry • Correlate specific IL-10 cytokine responses and chronic cytomegalovirus shedding in oral mucosa • Evaluate and test antibody cross-reactivity of anti-viral IL-10 antibodies to cellular IL-10 using ELISA, Western Blot and viral IL-10 neutralization assays • Evaluate and analyze changes in patterns of viral shedding in vaccinated animals via quantitative real-time PCR • Analyze permanently altered or transient immunological changes in vaccinated animals via ELISA, neutralization assays, avidity and flow cytometry assays

    • Staff Research Associate II
      • 2003 - May 2013

      • Assist in developing novel fluorescent virus neutralization assay • Assess the natural history of rhesus cytomegalovirus and B virus infection in rhesus macaques • Clone viral genes into expression vectors, for use in analysis of humoral immune responses via ELISA and Western blots, as well as in standards for qPCR • Perform qPCR, ELISA, Western, Neutralization assays for myriad projects running in the lab • Responsible for training, supervision of students and general lab… Show more • Assist in developing novel fluorescent virus neutralization assay • Assess the natural history of rhesus cytomegalovirus and B virus infection in rhesus macaques • Clone viral genes into expression vectors, for use in analysis of humoral immune responses via ELISA and Western blots, as well as in standards for qPCR • Perform qPCR, ELISA, Western, Neutralization assays for myriad projects running in the lab • Responsible for training, supervision of students and general lab maintenance

    • Student Assistant
      • 2003 - 2003

      • H&E staining of slide biopsy sections • Interface with surgical nursing staff and coordinate sample pick-up • H&E staining of slide biopsy sections • Interface with surgical nursing staff and coordinate sample pick-up

Education

  • UC Davis
    Doctor of Philosophy (Ph.D.), Comparative Pathology
    2007 - 2013
  • University of California, Davis
    BS, Biology
    1998 - 2003

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