Matthew Long
Data Scientist and Platform Engineer at Gatehouse Bio- Claim this Profile
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English Native or bilingual proficiency
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Experience
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Gatehouse Bio
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United States
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Biotechnology Research
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1 - 100 Employee
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Data Scientist and Platform Engineer
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Mar 2021 - Present
- Developed and executed machine learning (ML) pipelines to identify small RNA signatures of diseases from NGS data - Worked with partners to identify key disease endpoints - Implemented and evaluated methods for data normalization, discovery, and model interpretation - Generated analyses and visualizations for use in ad-hoc and standardized reports and presentations - Created data pipeline for new experimental technique - Identified acceptance criterion for replicate data - Developed and evaluated numeric endpoint allowing global comparison - Created reports showing results with propagated uncertainties, significance, and decision points - Developed internal packages following software best practices and to enable code reuse and traceability - Refactored existing pipeline scripts to functionalized R package allowing quicker prototyping - Developed reporting R package for standardized and automate reporting, data analysis, and figure generation - Developed and implemented figure and report identification and source data identification system
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Epic
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Brazil
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Graphic Design
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1 - 100 Employee
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Data Analytics Administrator
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Jan 2018 - Mar 2021
Manage and support SQL Server and reporting tools for hospital systems Development lead of Epic Hosting analytics team - Developed automated system management processes and pipelines - Developed remote issue identification, correction, and alerting systems - Project planning and prioritization lead Small team lead Manage and support SQL Server and reporting tools for hospital systems Development lead of Epic Hosting analytics team - Developed automated system management processes and pipelines - Developed remote issue identification, correction, and alerting systems - Project planning and prioritization lead Small team lead
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University of Wisconsin-Madison
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Higher Education
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700 & Above Employee
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Graduate Research Assistant
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Aug 2012 - Dec 2017
Research in the lab of Dr. Jennifer Reed • Developed method for the incorporation of experimental data into genome scale metabolic models • Analyzed and modelled gene expression, proteomics, and transposon seq data correlations to metabolic fluxes • Developed analysis pipeline for evaluating microbial potential of over 1,000 high production volume chemicals • Developed a method for finding the reduced dimensionality solution space from large linear programs • Lectured as a Teaching Assistant and received Roland A. Ragatz Award for best discussion section TA
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Penn State University
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United States
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Higher Education
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700 & Above Employee
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Research Assistant
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Aug 2009 - Jul 2012
Research in the lab of Dr. Andrew Zydney in collaboration with ChromaTan Inc. • Studied hydrodynamic properties of a resin slurry in hollow fiber membranes • Investigated Continuous Countercurrent Tangential Chromatography™ for mAb separation Research in the lab of Dr. Andrew Zydney in collaboration with ChromaTan Inc. • Studied hydrodynamic properties of a resin slurry in hollow fiber membranes • Investigated Continuous Countercurrent Tangential Chromatography™ for mAb separation
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Merck
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United States
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Pharmaceutical Manufacturing
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700 & Above Employee
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Internship
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May 2009 - Aug 2010
Two summers in Technical Operations at then Cherokee Pharmaceuticals (formerly and currently a plant of Merck) • Optimized filter dryer cycles and media types for an active pharmaceutical ingredient • Developed and implemented sampling procedures and batch cycle times to improve hydrogenation reaction • Developed protocol for utilizing a LabMax reactor system Two summers in Technical Operations at then Cherokee Pharmaceuticals (formerly and currently a plant of Merck) • Optimized filter dryer cycles and media types for an active pharmaceutical ingredient • Developed and implemented sampling procedures and batch cycle times to improve hydrogenation reaction • Developed protocol for utilizing a LabMax reactor system
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Geisinger Health System
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United States
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Medical Practices
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1 - 100 Employee
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Internship at the Sigfried and Janet Weis Center for Research
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Sep 2007 - Aug 2008
Co-op at the Sigfried and Janet Weis Center for Research under Dr. Gerda Breitwieser. • Imaged Ca2+ in mammalian cells to observe Calcium Sensing Receptor response • Assisted with various labs (PCR, western blots, gel electrophoresis, etc.) Co-op at the Sigfried and Janet Weis Center for Research under Dr. Gerda Breitwieser. • Imaged Ca2+ in mammalian cells to observe Calcium Sensing Receptor response • Assisted with various labs (PCR, western blots, gel electrophoresis, etc.)
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Education
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University of Wisconsin-Madison
Doctor of Philosophy (PhD), Chemical Engineering -
Penn State University
Master of Science (MS), Chemical Engineering -
Penn State University
Bachelor of Science (B.S.), Chemical Engineering